Dr. Eileen L. Berman and Stanley I. Berman Foundation Chair in Biomedical Research
Psychology And Neuroscience & Behavior Program
Health Informatics And Implementation Science
Cutler Chair in Vascular and Endovascular Surgery
Clinical research opportunities are available for medical and PhD students, residents and junior faculty upon request. We are currently not hiring paid research staff. We cannot accept basic scientists. Please read up on our research first before applying.
Dr. Muehlschlegel is a neurointensivist devoted to improving the care of patients with catastrophic neurological injuries. Her research interests concentrate on outcome prognostication in neurocritical care, particularly in moderate-severe traumatic brain injury. She is the principal investigator for several research studies at the UMASS Neuro-Intensive care unit (NeuroICU).
Robert M. and Shirley S. Siff Chair in Autism
Melvin S. and Sandra L. Cutler Chair in Biomedical Research
A postdoc position is available to study in Dr. Ceol's lab.Click here to apply.
Dr. Chu is an epileptologist who cares for patients in the inpatient and outpatient settings.
Dr. Henninger is a vascular neurologist with research interest in the neurobiology of axonal injury associated with traumatic brain injury and its contribution to functional outcome.
A postdoctoral position is available to study in this laboratory. Contact Dr. Rogaev for additional details.
Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
Barbara Helen Smith Chair in Preventive & Behavioral Medicine
Susan Lynn Sullivan-Bolyai DNSc, MN, RN, CNS, FAAN
Rotation Projects Please contact Nathan Lawson (nathan.lawson@umassmed.edu) for information regarding potential rotation projects. For information concerning recent research in the lab, please see:lawsonlab.umassmed.edu/research.html
Joseph J. Byrne Chair in Biomedical Research
? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
Richard M. Haidack Professor in Medicine
Dr. John Meyers Professor in Primary Care Medicine
Population and Quantitative Health Sciences
Dr. Rossi is a board-certified clinical neurologist and epileptologist with subspecialty certifications in Clinical Neurophysiology and Epilepsy. His primary clinical and research interests include long-term EEG monitoring in critically ill patients, quantitative EEG analysis, pharmacology of anticonvulsant medications, and the surgical evaluation and treatment of drug-resistant epilepsy.
Biochemistry and Molecular Biotechnology
Prevention Research Center at UMass Chan
Tweets by @DrSherryPagoto
Healthcare Delivery and Population Sciences at UMass Chan - Baystate
Priscilla K. Gazarian PhD, CNS, RN, FAAN
Priscilla Gazarian, PhD CNS RN, is Professor of Nursing and Associate Dean for Academic Affairs in the Tan Chingfen Graduate School of Nursing.
Joseph D. Early Chair in Biomedical Research
Dr. Wilcox trained in EM at the Harvard Affiliated EM Residency, then completed an Anesthesia Critical Care fellowship. In addition to the ED, she has attended in Surgical, Medical, and Cardiac ICUs. She joined Lahey Hospital in 2022 as the Medical Director of the 5C Medical ICU. She is Vice Chair for Academic Affairs and a Professor of Medicine. She is the Associate CMO for Boston MedFlight.
EMCrit 181 – Pulmonary Hypertension and Right Ventricular Failure with Susan Wilcox
HarvardX: Mechanical Ventilation for COVID-19
CritCases 7 Pulmonary Hypertension – A Fine Balance
Academic Life in Emergency Medicine: The Myth of Vasopressors and Ischemia
ACEP COVID-19 Field Guide: ICU Care in the Emergency Department
Podcast summary of articles from the June 2021 edition of the Journal of Emergency Medicine