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Lapane, Kate
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Puri, Ajit
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Henninger, Nils
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Heneka, Michael
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Jacelon, Cynthia
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Karlstrom, Rolf
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McClements, David
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Spencer, Rebecca
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Rogaev, Evgeny
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rogaev for additional details.
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Crawford, Sybil
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Wolfe, Scot
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Post Docs: Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Rotation Projects: Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
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Lemon, Stephenie
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Endowed Chair Honorary Title: Barbara Helen Smith Chair in Preventive & Behavioral Medicine
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Sullivan-Bolyai, Susan
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Lawson, Nathan
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Rotation Projects: Rotation Projects Please contact Nathan Lawson (nathan.lawson@umassmed.edu) for information regarding potential rotation projects. For information concerning recent research in the lab, please see:lawsonlab.umassmed.edu/research.html
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Dekker, Job
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Endowed Chair Honorary Title: Joseph J. Byrne Chair in Biomedical Research
Rotation Projects: ? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
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Goldberg, Robert
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Shaw, Leslie
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McManus, David
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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Pediatric Genetics
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Friedmann, Peter
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UMass Chan – Baystate Regional Campus
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Steingrub, Jay
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Singh, Sonal
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Person ID: 4649
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Lagu, Tara
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Associate Professor
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Associate Professor
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Chair and Professor
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Fergus Clydesdale Endowed Chair
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Lindenauer, Peter
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Copeland, Laurel
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ADJUNCT PROFESSOR
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Gurwitz, Jerry
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Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
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Usmani, Saad
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Strauss, Kevin
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Population and Quantitative Health Sciences
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Schlaug, Gottfried
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Rossi, Kyle
first name: Kyle
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Summary: Dr. Rossi is a board-certified clinical neurologist and epileptologist with subspecialty certifications in Clinical Neurophysiology and Epilepsy. His primary clinical and research interests include long-term EEG monitoring in critically ill patients, quantitative EEG analysis, pharmacology of anticonvulsant medications, and the surgical evaluation and treatment of drug-resistant epilepsy.
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Gerber, Ben
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Biochemistry and Molecular Biotechnology
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Lin, Honghuang
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Matteson, Kristen
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https://profiles.umassmed.edu/profile/28866492
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Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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Medicine at UMass Chan - Baystate
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Neurology at UMass Chan - Baystate
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Professor
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Adjunct Professor
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Assistant Professor
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Professor
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Thyme, Summer
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Adjunct Professor
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Professor
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Associate Professor
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Walkey, Allan
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Genomics and Computational Biology
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Mosenthal, Anne
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person in primary position: Professor
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Medicine at UMass Chan - Lahey
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Surgery at UMass Chan - Lahey
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Radiology at UMass Chan - Lahey
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Chair and Professor
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Professor
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Health System Science
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Infectious Diseases
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Neurointerventional Radiology
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Pulmonary Medicine
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Professor Emeritus
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Professor
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Associate Professor
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Professor
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Professor
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Professor
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Professor
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Adjunct Professor
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Assistant Professor
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Associate Professor
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Professor
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Professor
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Adjunct Professor
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Epilepsy
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Neurocritical Care
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Ob/Gyn General
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Stroke and Vascular Neurology
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Chair and Professor
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Neurology at UMass Chan - Lahey
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Professor
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Professor
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Professor
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Tan Chingfen Graduate School of Nursing
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Professor
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Professor Emeritus
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McAlindon, Timothy
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person in primary position: Professor
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Gazarian, Priscilla
first name: Priscilla
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Person ID: 10247867
person in primary position: Professor
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Summary: Priscilla Gazarian, PhD CNS RN, is Professor of Nursing and Associate Dean for Academic Affairs in the Tan Chingfen Graduate School of Nursing.
preferred title: Professor

Professor
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sort order: 1
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position in organization: UMass Chan Medical School

Martinez, Fernando
first name: Fernando
last name: Martinez
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Person ID: 10247895
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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position in department: Medicine
position in division: Pulmonary Medicine
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Wilcox, Susan
first name: Susan
last name: Wilcox
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media links: https://profiles.umassmed.edu/profile/66924233
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media links: https://profiles.umassmed.edu/profile/66923911
Person ID: 10247922
person in primary position: Professor
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Summary: Dr. Wilcox trained in EM at the Harvard Affiliated EM Residency, then completed an Anesthesia Critical Care fellowship. In addition to the ED, she has attended in Surgical, Medical, and Cardiac ICUs. She joined Lahey Hospital in 2022 as the Medical Director of the 5C Medical ICU. She is Vice Chair for Academic Affairs and a Professor of Medicine. She is the Associate CMO for Boston MedFlight.
preferred title: Professor

Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
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Professor
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Krings, Timo
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last name: Krings
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person in primary position: Professor
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Professor Emeritus
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HR job title: Professor Emeritus
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Maron, Martin
first name: Martin
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Person ID: 10248121
person in primary position: Associate Professor
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Maron, Barry
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Adjunct Professor
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Professor
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position in division: Rheumatology
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Chair and Professor
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position in organization: UMass Chan – Baystate Regional Campus

Associate Professor
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Reynolds, Matthew
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person in primary position: Professor
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Professor
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Ganatra, Sarju
first name: Sarju
last name: Ganatra
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Person ID: 10248218
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Assistant Professor
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Instructor
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Professor
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Professor Emeritus
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Assistant Professor
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Associate Professor
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Chair And Professor
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Professor Emeritus
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Psychiatry and Behavioral Sciences
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Professor
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Professor
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Professor
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Professor
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position in division: Preventive And Behavioral Medicine
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HR job title: Professor
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Associate Professor
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position in department: Neurology
position in division: Stroke and Vascular Neurology
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
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position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Health System Science
sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/66923911
publication date: 2016
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label: https://emcrit.org/emcrit/pulmonary-hypertension-right-ventricular-failure/
link anchor text: EMCrit 181 – Pulmonary Hypertension and Right Ventricular Failure with Susan Wilcox

https://profiles.umassmed.edu/profile/66923959
publication date: 2020
type: URLLink
label: https://www.edx.org/learn/healthcare/harvard-university-mechanical-ventilation-for-covid-19
link anchor text: HarvardX: Mechanical Ventilation for COVID-19

https://profiles.umassmed.edu/profile/66924015
publication date: 2017
type: URLLink
label: https://emergencymedicinecases.com/pulmonary-hypertension/
link anchor text: CritCases 7 Pulmonary Hypertension – A Fine Balance

https://profiles.umassmed.edu/profile/66924043
publication date: 2018
type: URLLink
label: https://www.aliem.com/2018/06/myth-vasopressors-ischemia/
link anchor text: Academic Life in Emergency Medicine: The Myth of Vasopressors and Ischemia

https://profiles.umassmed.edu/profile/66924060
publication date: 2020
type: URLLink
label: https://www.acep.org/corona/covid-19-field-guide/treatment/icu-care-in-the-emergency-department/
link anchor text: ACEP COVID-19 Field Guide: ICU Care in the Emergency Department

https://profiles.umassmed.edu/profile/66924233
publication date: 2021
type: URLLink
label: https://podcasts.apple.com/us/podcast/jem-june-2021-podcast-summary/id1141686910
link anchor text: Podcast summary of articles from the June 2021 edition of the Journal of Emergency Medicine

Associate Professor
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position in department: Molecular, Cell and Cancer Biology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
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Associate Professor
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position in department: Medicine at UMass Chan - Lahey
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sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Radiology at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Pediatrics
position in division: Pediatric Genetics
sort order: 1
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Neurology at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School