Jayawardena HS, Wang X, Yan M. Classification of lectins by pattern recognition using glyconanoparticles. Anal Chem. 2013 Nov 05; 85(21):10277-81.
Classification of lectins by pattern recognition using glyconanoparticles.
Hao N, Jayawardana KW, Chen X, Yan M. One-step synthesis of amine-functionalized hollow mesoporous silica nanoparticles as efficient antibacterial and anticancer materials. ACS Appl Mater Interfaces. 2015 Jan 21; 7(2):1040-5.
One-step synthesis of amine-functionalized hollow mesoporous silica nanoparticles as efficient antibacterial and anticancer materials.
Park J, Jayawardena HS, Chen X, Jayawardana KW, Sundhoro M, Ada E, Yan M
Chemical communications (Cambridge, England)
Park J, Jayawardena HS, Chen X, Jayawardana KW, Sundhoro M, Ada E, Yan M. A general method for the fabrication of graphene-nanoparticle hybrid material. Chem Commun (Camb). 2015 Feb 18; 51(14):2882-5.
A general method for the fabrication of graphene-nanoparticle hybrid material.
Jayawardana KW, Jayawardena HS, Wijesundera SA, De Zoysa T, Sundhoro M, Yan M
Jayawardana KW, Jayawardena HS, Wijesundera SA, De Zoysa T, Sundhoro M, Yan M. Selective targeting of Mycobacterium smegmatis with trehalose-functionalized nanoparticles. Chem Commun (Camb). 2015 Aug 04; 51(60):12028-31.
Selective targeting of Mycobacterium smegmatis with trehalose-functionalized nanoparticles.
Lisa Abdallah PhD Nursing & Health Policy, MS Nursing Administra
Susan Woskie M.S. Occupational & Environmental Hygiene, Ph.D. B
Positions for postdoctoral fellows are available in the laboratory of Dr. Gang Han at the Department of Biochemistry and Molecular Pharmacology of The University of Massachusetts- Medical School. Research will focus on developing novel small molecule/ nanoparticle approaches for translational biomedical sciences and molecular imaging. Qualifications: Candidates have a Ph.D degree in (1)Organic Chemistry/polymer synthesis , (2) Molecular cell biology , (3) Biophysics or (4) Biochemistry. A solid training and substantial organic synthesis, animal experiments, spectroscopy and microscopy are desired. Candidates need to have strong work ethic, creativity, and enthusiasm with proven ability to work independently and collaboratively. To apply: Applicants should submit their CV including a full publication list and sources of three reference letters by email to gang.han@umassmed.edu
Rotation projects <p >(1) Specific cell membrane component labeling using bioconjugated nanoparticles <p >(2) To develop tools for targeted and traceable siRNA delivery <p >(3) To synthesize functional nanomaterials for detecting biomarkers in biological fluids
Jayawardana KW, Wijesundera SA, Yan M. Aggregation-based detection of M. smegmatis using D-arabinose-functionalized fluorescent silica nanoparticles. Chem Commun (Camb). 2015 Nov 14; 51(88):15964-6.
Aggregation-based detection of M. smegmatis using D-arabinose-functionalized fluorescent silica nanoparticles.
Hao N, Neranon K, Ramstr?m O, Yan M. Glyconanomaterials for biosensing applications. Biosens Bioelectron. 2016 Feb 15; 76:113-30.
Glyconanomaterials for biosensing applications.
Hao N, Chen X, Jayawardana KW, Wu B, Sundhoro M, Yan M
Hao N, Chen X, Jayawardana KW, Wu B, Sundhoro M, Yan M. Shape control of mesoporous silica nanomaterials templated with dual cationic surfactants and their antibacterial activities. Biomater Sci. 2016 Jan; 4(1):87-91.
Shape control of mesoporous silica nanomaterials templated with dual cationic surfactants and their antibacterial activities.
Hao N, Chen X, Jeon S, Yan M. Carbohydrate-Conjugated Hollow Oblate Mesoporous Silica Nanoparticles as Nanoantibiotics to Target Mycobacteria. Adv Healthc Mater. 2015 Dec 30; 4(18):2797-801.
Carbohydrate-Conjugated Hollow Oblate Mesoporous Silica Nanoparticles as Nanoantibiotics to Target Mycobacteria.
Sundhoro M, Wang H, Boiko ST, Chen X, Jayawardena HS, Park J, Yan M
Sundhoro M, Wang H, Boiko ST, Chen X, Jayawardena HS, Park J, Yan M. Fabrication of carbohydrate microarrays on a poly(2-hydroxyethyl methacrylate)-based photoactive substrate. Org Biomol Chem. 2016 Jan 21; 14(3):1124-30.
Fabrication of carbohydrate microarrays on a poly(2-hydroxyethyl methacrylate)-based photoactive substrate.
Chen X, Wu B, Jayawardana KW, Hao N, Jayawardena HS, Langer R, Jaklenec A, Yan M
Chen X, Wu B, Jayawardana KW, Hao N, Jayawardena HS, Langer R, Jaklenec A, Yan M. Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria. Adv Healthc Mater. 2016 08; 5(16):2007-12.
Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria.
Chen X, Ramstr?m O, Yan M. Glyconanomaterials: Emerging applications in biomedical research. Nano Res. 2014 Oct; 7(10):1381-1403.
Glyconanomaterials: Emerging applications in biomedical research.
Uppalapati S, Kong N, Norberg O, Ramstr?m O, Yan M
Uppalapati S, Kong N, Norberg O, Ramstr?m O, Yan M. Ionization of covalent immobilized poly(4-vinylphenol) monolayers measured by ellipsometry, QCM and SPR. Appl Surf Sci. 2015 Jul 15; 343:166-171.
Ionization of covalent immobilized poly(4-vinylphenol) monolayers measured by ellipsometry, QCM and SPR.
Sundhoro M, Park J, Jayawardana KW, Chen X, Jayawardena HSN, Yan M
Journal of colloid and interface science
Sundhoro M, Park J, Jayawardana KW, Chen X, Jayawardena HSN, Yan M. Poly(HEMA-co-HEMA-PFPA): Synthesis and preparation of stable micelles encapsulating imaging nanoparticles. J Colloid Interface Sci. 2017 Aug 15; 500:1-8.
Poly(HEMA-co-HEMA-PFPA): Synthesis and preparation of stable micelles encapsulating imaging nanoparticles.
Xie S, Zhang Y, Ramstr?m O, Yan M. Base-catalyzed synthesis of aryl amides from aryl azides and aldehydes. Chem Sci. 2016 Jan 01; 7(1):713-718.
Base-catalyzed synthesis of aryl amides from aryl azides and aldehydes.
Sundhoro M, Jeon S, Park J, Ramstr?m O, Yan M
Angewandte Chemie (International ed. in English)
Sundhoro M, Jeon S, Park J, Ramstr?m O, Yan M. Perfluoroaryl Azide Staudinger Reaction: A Fast and Bioorthogonal Reaction. Angew Chem Int Ed Engl. 2017 09 25; 56(40):12117-12121.
Perfluoroaryl Azide Staudinger Reaction: A Fast and Bioorthogonal Reaction.
Ndugire W, Wu B, Yan M. Synthesis of Carbohydrate-Grafted Glycopolymers Using a Catalyst-Free, Perfluoroarylazide-Mediated Fast Staudinger Reaction. Molecules. 2019 Jan 03; 24(1).
Synthesis of Carbohydrate-Grafted Glycopolymers Using a Catalyst-Free, Perfluoroarylazide-Mediated Fast Staudinger Reaction.
Wu B, Yang X, Yan M. Synthesis and Structure-Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens. J Med Chem. 2019 09 12; 62(17):7751-7768.
Synthesis and Structure-Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens.
Park J, Jin T, Liu C, Li G, Yan M. Three-Dimensional Graphene-TiO2 Nanocomposite Photocatalyst Synthesized by Covalent Attachment. ACS Omega. 2016 Sep 30; 1(3):351-356.
Three-Dimensional Graphene-TiO2 Nanocomposite Photocatalyst Synthesized by Covalent Attachment.
Liyanage SH, Yan M. Quantification of binding affinity of glyconanomaterials with lectins. Chem Commun (Camb). 2020 Nov 14; 56(88):13491-13505.
Quantification of binding affinity of glyconanomaterials with lectins.
Perera HA, Yan M. Imaging, Identification and Inhibition of Microorganisms Using AIEgens. Top Curr Chem (Cham). 2021 Apr 09; 379(3):21.
Imaging, Identification and Inhibition of Microorganisms Using AIEgens.
Yang X, Chen F, Kim MA, Liu H, Wolf LM, Yan M
Chemistry (Weinheim an der Bergstrasse, Germany)
Yang X, Chen F, Kim MA, Liu H, Wolf LM, Yan M. On the Reactivity Enhancement of Graphene by Metallic Substrates towards Aryl Nitrene Cycloadditions. Chemistry. 2021 May 20; 27(29):7887-7896.
On the Reactivity Enhancement of Graphene by Metallic Substrates towards Aryl Nitrene Cycloadditions.
Ndugire W, Raviranga NGH, Lao J, Ramstr?m O, Yan M
Ndugire W, Raviranga NGH, Lao J, Ramstr?m O, Yan M. Gold Nanoclusters as Nanoantibiotic Auranofin Analogues. Adv Healthc Mater. 2022 05; 11(9):e2101032.
Gold Nanoclusters as Nanoantibiotic Auranofin Analogues.
Biochemistry and Molecular Biotechnology
Ndugire W, Yan M. Synthesis and solution isomerization of water-soluble Au9 nanoclusters prepared by nuclearity conversion of [Au11(PPh3)8Cl2]Cl. Nanoscale. 2021 Oct 14; 13(39):16809-16817.
Synthesis and solution isomerization of water-soluble Au9 nanoclusters prepared by nuclearity conversion of [Au11(PPh3)8Cl2]Cl.
Wu B, Ndugire W, Chen X, Yan M. Maltoheptaose-Presenting Nanoscale Glycoliposomes for the Delivery of Rifampicin to E. coli. ACS Appl Nano Mater. 2021 Jul 23; 4(7):7343-7357.
Maltoheptaose-Presenting Nanoscale Glycoliposomes for the Delivery of Rifampicin to E. coli.
Park J, Yang X, Wickramasinghe D, Sundhoro M, Orbey N, Chow KF, Yan M
Park J, Yang X, Wickramasinghe D, Sundhoro M, Orbey N, Chow KF, Yan M. Functionalization of pristine graphene for the synthesis of covalent graphene-polyaniline nanocomposite. RSC Adv. 2020 Jul 09; 10(44):26486-26493.
Functionalization of pristine graphene for the synthesis of covalent graphene-polyaniline nanocomposite.
Wijesundera SA, Liyanage SH, Biswas P, Reuther JF, Yan M
Wijesundera SA, Liyanage SH, Biswas P, Reuther JF, Yan M. Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria. Biomacromolecules. 2023 01 09; 24(1):238-245.
Trehalose-Grafted Glycopolymer: Synthesis via the Staudinger Reaction and Capture of Mycobacteria.
Physical chemistry chemical physics : PCCP
Yang X, Chen F, Kim MA, Liu H, Wolf LM, Yan M. Using metal substrates to enhance the reactivity of graphene towards Diels-Alder reactions. Phys Chem Chem Phys. 2022 Aug 31; 24(34):20082-20093.
Using metal substrates to enhance the reactivity of graphene towards Diels-Alder reactions.
Wijesundera SA, Jayawardana KW, Yan M. Trehalose-Modified Silver Nanoparticles as Antibacterial Agents with Reduced Cytotoxicity and Enhanced Uptake by Mycobacteria. ACS Appl Nano Mater. 2022 Aug 26; 5(8):10704-10714.
Trehalose-Modified Silver Nanoparticles as Antibacterial Agents with Reduced Cytotoxicity and Enhanced Uptake by Mycobacteria.
Ndugire W, Truong D, Hasitha Raviranga NG, Lao J, Ramstr?m O, Yan M
Ndugire W, Truong D, Hasitha Raviranga NG, Lao J, Ramstr?m O, Yan M. Turning on the Antimicrobial Activity of Gold Nanoclusters Against Multidrug-Resistant Bacteria. Angew Chem Int Ed Engl. 2023 03 06; 62(11):e202214086.
Turning on the Antimicrobial Activity of Gold Nanoclusters Against Multidrug-Resistant Bacteria.
Liyanage SH, Raviranga NGH, Ryan JG, Shell SS, Ramstr?m O, Kalscheuer R, Yan M
Liyanage SH, Raviranga NGH, Ryan JG, Shell SS, Ramstr?m O, Kalscheuer R, Yan M. Azide-Masked Fluorescence Turn-On Probe for Imaging Mycobacteria. JACS Au. 2023 Apr 24; 3(4):1017-1028.
Azide-Masked Fluorescence Turn-On Probe for Imaging Mycobacteria.
Chen X, Wu B, Perera HA, Yan M. Synthesis of Glycopolymer Micelles for Antibiotic Delivery. Molecules. 2023 May 11; 28(10).
Synthesis of Glycopolymer Micelles for Antibiotic Delivery.
Liyanage SH, Yan M. Maltose-Derivatized Fluorescence Turn-On Imaging Probe for Bacteria Detection. ACS Infect Dis. 2023 12 08; 9(12):2560-2571.
Maltose-Derivatized Fluorescence Turn-On Imaging Probe for Bacteria Detection.
Raviranga NGH, Ayinla M, Perera HA, Qi Y, Yan M, Ramstr?m O
Raviranga NGH, Ayinla M, Perera HA, Qi Y, Yan M, Ramstr?m O. Antimicrobial Potency of Nor-Pyochelin Analogues and Their Cation Complexes against Multidrug-Resistant Pathogens. ACS Infect Dis. 2024 11 08; 10(11):3842-3852.
Antimicrobial Potency of Nor-Pyochelin Analogues and Their Cation Complexes against Multidrug-Resistant Pathogens.
Small (Weinheim an der Bergstrasse, Germany)
Tu J, Yan M. Enhancing the Chemical Reactivity of Graphene through Substrate Engineering. Small. 2024 Dec 19; e2408116.
Enhancing the Chemical Reactivity of Graphene through Substrate Engineering.
Tu J, Zhou W, Kiani A, Wolf LM, Yan M. Chemical Vapor Deposition of Monolayer Graphene on Centimeter-Sized Cu(111) for Nanoelectronics Applications. ACS Appl Nano Mater. 2025 Mar 07; 8(9):4926-4939.
Chemical Vapor Deposition of Monolayer Graphene on Centimeter-Sized Cu(111) for Nanoelectronics Applications.
Park J, Yan M. Covalent functionalization of graphene with reactive intermediates. Acc Chem Res. 2013 Jan 15; 46(1):181-9.
Covalent functionalization of graphene with reactive intermediates.
Norberg O, Wu B, Thota N, Ge JT, Fauquet G, Saur AK, Aastrup T, Dong H, Yan M, Ramstr?m O
Norberg O, Wu B, Thota N, Ge JT, Fauquet G, Saur AK, Aastrup T, Dong H, Yan M, Ramstr?m O. Synthesis and binding affinity analysis of a1-2- and a1-6-O/S-linked dimannosides for the elucidation of sulfur in glycosidic bonds using quartz crystal microbalance sensors. Carbohydr Res. 2017 Nov 27; 452:35-42.
Synthesis and binding affinity analysis of a1-2- and a1-6-O/S-linked dimannosides for the elucidation of sulfur in glycosidic bonds using quartz crystal microbalance sensors.
Kong N, Shimpi MR, Ramstr?m O, Yan M. Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides. Carbohydr Res. 2015 Mar 20; 405:33-8.
Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides.
Xie S, Zhou J, Chen X, Kong N, Fan Y, Zhang Y, Hammer G, Castner DG, Ramstr?m O, Yan M
Xie S, Zhou J, Chen X, Kong N, Fan Y, Zhang Y, Hammer G, Castner DG, Ramstr?m O, Yan M. A Versatile Catalyst-Free Perfluoroaryl Azide-Aldehyde-Amine Conjugation Reaction. Mater Chem Front. 2019 Feb 01; 3(2):251-256.
A Versatile Catalyst-Free Perfluoroaryl Azide-Aldehyde-Amine Conjugation Reaction.
Ramstr?m O, Yan M. Glyconanomaterials for Combating Bacterial Infections. Chemistry. 2015 Nov 09; 21(46):16310-7.
Glyconanomaterials for Combating Bacterial Infections.
Wang H, Tong Q, Yan M. Antifouling surfaces for proteins labeled with dye-doped silica nanoparticles. Anal Chem. 2013 Jan 02; 85(1):23-7.
Antifouling surfaces for proteins labeled with dye-doped silica nanoparticles.
Jayawardena HS, Jayawardana KW, Chen X, Yan M
Jayawardena HS, Jayawardana KW, Chen X, Yan M. Maltoheptaose promotes nanoparticle internalization by Escherichia coli. Chem Commun (Camb). 2013 Apr 14; 49(29):3034-6.
Maltoheptaose promotes nanoparticle internalization by Escherichia coli.