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Kim, Jason
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Summary: My research for almost 30 years has focused on obesity, insulin resistance, and type 2 diabetes and explores the molecular link between inflammation and insulin resistance using transgenic mice with elegant in vivo metabolic experiments and molecular approaches. My research also investigates the role of inflammation and altered metabolism in diabetic heart disease.
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Allison, Jeroan
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Rotation Projects: Potential Rotation Projects Proteostasis regulators, HSF1, HSP70 and HSP90 in liver disease: Determine the expression and function in different cell types of the liver during acute and chronic liver injury using in vivo and in vitro models. Subsequently, we will test the relevance of the expression of these proteins in activation of intracellular signaling molecules involved in induction of fatty liver, inflammation and fibrosis. Role of chemokines in liver disease: CC-chemokines particularly CCL2/MCP-1, is significantly increased in serum as well as in the liver parenchyma in patients with alcoholic hepatitis. We test the role of MCP-1 in induction of fatty acid synthesis or metabolism and inflammation in the alcoholic liver. Our studies will also investigate the role of MCP-1 directed migration of immune cells in the liver contributing to injury.
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Mazor, Kathleen
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Shultz, Leonard
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Czech, Michael
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Endowed Chair Honorary Title: Isadore and Fannie Foxman Chair in Medical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Czech for additional details.
Rotation Projects: Mentoring……………………………………………………………………………………………………… The Czech laboratory is active in mentoring graduate students and postdoctoral fellows. Many former student and postdoctoral trainees of the Czech laboratory are now internationally recognized professors at major universities and medical schools. These former lab members include: Paul Pilch, Professor of Biochemistry, Boston University School of Medicine Jeffrey Pessin, Professor and Director of the Diabetes Center, Einstein College of Medicine Joan Massague, Director, Sloan Kettering Institute Roger Davis, HHMI investigator and Professor of Molecular Medicine, UMASS Medical School Silvia Corvera, Professor of Molecular Medicine, Co-Director of the MD/PhD Program, UMASS Medical School Carla Greenbaum, Vice Chair and Director of Clinical Research, Benaroya Research Institute Jes Klarlund, Professor of Ophthalmology, University of Pittsburgh Medical Center Rob Lewis, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Richard MacDonald, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Assia Shisheva, Professor of Physiology, Wayne State School of Medicine. Mark Sleeman, Professor of Physiology, Monash University, Australia John Harris, Associate Professor of Medicine, UMASS Medical School Zhen Jiang, Associate Professor of Pharmacology and Medicine, Boston University Vishu Puri, Professor of Biomedical Sciences, Ohio University Olga Gupta, Assistant Professor of Pediatrics and Medicine, University of Texas Southwestern Medical Center Tim Fitzgibbons, Assistant Professor of Medicine, UMASS Medical School Myriam Aouadi, Assistant Professor, Integrated Cardio Metabolic Centre, Karolinska Institute Adilson Guilherme, Associate Professor, University of Massachusetts Medical School Our laboratory currently offers graduate student Rotation Projects (examples below and others available) and Thesis Research …
preferred title: Professor Emeritus

Davis, Roger
first name: Roger
last name: Davis
full name: Roger J Davis PhD, FRS
has faculty rank: Chair And Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
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Person ID: 3130
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866429

Zierath, Juleen
first name: Juleen
last name: Zierath
full name: Juleen R Zierath PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27587600000000
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Person ID: 3151
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Lapane, Kate
first name: Kate
last name: Lapane
full name: Kate L Lapane PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
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Person ID: 3252
person in primary position: Professor
type: Agent
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preferred title: Professor

Rock, Kenneth
first name: Kenneth
last name: Rock
full name: Kenneth L Rock MD
has faculty rank: Chair And Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 332
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: UMass Chan Medical School Chair in Biomedical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rock for additional details.
Rotation Projects: Potential Rotation Projects <p >Rotations are available in Dr. Rock’s laboratory for graduate students in the GSBS program. The rotation projects will explore various aspects of how the immune system carries out surveillance to detect viral infections and cancers. Among the potential areas of research are: (1) The alarm signals that alert the immune system to potential danger; (2) The initial innate immune and inflammatory response to infection or other dangerous situations; (3) The biology of the sentinel cells (e.g. dendritic cells) that sense danger and report it the adaptive immune system; (4) The mechanisms by which sentinel cells (e.g. dendritic cells) acquire and display antigens to T cells; and, (5) The antigen presentation pathways by which virally infected or cancer cells display a sampling of their expressed gene products to the activated T cells. Specific rotation projects are chosen based on the student’s interests and state/availability of the various projects in the laboratory. The goals of rotations are for the student to gain knowledge in immunology, to learn how to approach experimental problems, to learn new techniques and methods, and to actually generate data that moves our knowledge forward. In addition, the rotation provides the student the opportunity to evaluate the laboratory as a possible place to conduct their thesis research in the future.
preferred title: Chair and Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
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longitude: 7.10034010000000
Person ID: 3432
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Behar, Samuel
first name: Samuel
last name: Behar
full name: Samuel M Behar MD, PhD
has faculty rank: Professor
latitude: 42.33730900000000
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Person ID: 3437
person in primary position: Professor
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Lab URL: https://www.umassmed.edu/maps/research-labs/behar/
Rotation Projects: LAB ROTATION PROJECTS AVAILABLE -- PLEASE CONTACT SAM BEHAR FOR MORE INFORMATION
Summary: Focus: We seek to understand how the causative agent of tuberculosis, namely the bacterium Mycobacterium tuberculosis evades host immunity, and how different components of the immune response work together to contain infection. Our ultimate goal is to inform vaccine development and the design of host directed therapy.
preferred title: Professor

Golenbock, Douglas
first name: Douglas
last name: Golenbock
full name: Douglas T Golenbock MD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 345
person in primary position: Professor
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Endowed Chair Honorary Title: Neil and Margery Blacklow Chair in Infectious Diseases and Immunology
preferred title: Professor

Garelnabi, Mahdi
first name: Mahdi
last name: Garelnabi
full name: Mahdi Garelnabi BS., MLT, MSc., Ph.D
has faculty rank: Assistant Professor
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Person ID: 3538
person in primary position: https://profiles.umassmed.edu/profile/16237428
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Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27636250000000
longitude: -71.76564740000000
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Person ID: 36
person in primary position: Adjunct Professor
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Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Hayman, Laura
first name: Laura
last name: Hayman
full name: Laura L Hayman PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.31573630000000
longitude: -71.05274820000000
Person ID: 3620
person in primary position: Adjunct Professor
type: Agent
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preferred title: Adjunct Professor

Chasan-Taber, Lisa
first name: Lisa
last name: Chasan-Taber
full name: Lisa Chasan-Taber MPH, ScD
has faculty rank: Professor
latitude: 42.39565560000000
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Person ID: 3699
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Haran, John
first name: John
last name: Haran
full name: John P Haran MD, PhD
has faculty rank: Professor
latitude: 42.27525000000000
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Person ID: 37
person in primary position: Professor
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Rotation Projects: Rotation projects are available related to microbiota-gut brain axis and antibiotic usage and the sequelae of antibiotic use in hospitalized patients which include Clostridium difficile and multi-drug resistant organism infection and colonization.
preferred title: Professor

Lian, Jane
first name: Jane
last name: Lian
full name: Jane B Lian PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27723620000000
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Person ID: 370
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Bertone-Johnson, Elizabeth
first name: Elizabeth
last name: Bertone-Johnson
full name: Elizabeth R Bertone-Johnson ScD SM
has faculty rank: Associate Professor
latitude: 42.39565560000000
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Person ID: 3724
person in primary position: Associate Professor
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type: Person
preferred title: Associate Professor

Rotello, Vincent
first name: Vincent
last name: Rotello
full name: Vincent Rotello PhD
has faculty rank: Professor
latitude: 42.39565560000000
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Person ID: 3741
person in primary position: Department Head
type: Agent
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preferred title: Department Head

Black, Samuel
first name: Samuel
last name: Black
full name: Samuel J Black PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3754
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

McClements, David
first name: David
last name: McClements
full name: David J McClements B.S., Ph.D.
has faculty rank: Professor
latitude: 42.39565560000000
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Person ID: 3760
person in primary position: Fergus Clydesdale Endowed Chair
type: Agent
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preferred title: Fergus Clydesdale Endowed Chair

Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3795
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Poudel, Krishna
first name: Krishna
last name: Poudel
full name: Krishna Poudel PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
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Person ID: 3832
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Brehm, Michael
first name: Michael
last name: Brehm
full name: Michael A Brehm PhD
has faculty rank: Professor
latitude: 42.27694690000000
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Person ID: 474
person in primary position: Professor
type: Agent
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Endowed Chair Honorary Title: Harvey A. Shultz Chair in Diabetes
preferred title: Professor

Rosal, Milagros
first name: Milagros
last name: Rosal
full name: Milagros Rosal PhD
has faculty rank: Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
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Person ID: 594
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Imoigele P. Aisiku, MD’97 Chair in Health Equity and Diversity
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866430

Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 612
person in primary position: Professor
type: Agent
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
preferred title: Professor

Ruiz De Luzuriaga, Katherine
first name: Katherine
last name: Ruiz De Luzuriaga
full name: Katherine Ruiz De Luzuriaga MD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
Person ID: 651
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: UMass Memorial Health Care Chair in Biomedical Research
Rotation Projects: Potential Rotation Projects: Contact Dr. Luzuriaga for project details.
preferred title: Professor

Kornfeld, Hardy
first name: Hardy
last name: Kornfeld
full name: Hardy Kornfeld MD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 739
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 78
person in primary position: Professor Emeritus
type: Agent
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preferred title: Professor Emeritus

Sassetti, Christopher
first name: Christopher
last name: Sassetti
full name: Christopher M Sassetti PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
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Person ID: 878
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Elisabeth Chair II
Lab URL: https://www.umassmed.edu/sassettilab/
Rotation Projects: Rotation Projects <p >We have identified a number of bacterial pathways that are required for bacterial viability or virulence. We are particularly interested in: Phosphosignaling systems that regulate cell wall synthesis Metabolic regulatory mechanisms that trigger the “dormancy” response observed during infection. <p >A variety of genetic, biochemical, and informatic methods will be used to define the functions of these genes and the role played by each during infection. <p >
Summary: Focus: Pathogenesis of tuberculosis
preferred title: Professor

Shaw, Leslie
first name: Leslie
last name: Shaw
full name: Leslie M Shaw PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 900
person in primary position: Professor
type: Agent
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preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866558

Mercurio, Arthur
first name: Arthur
last name: Mercurio
full name: Arthur M Mercurio PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 901
person in primary position: Professor
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
preferred title: Professor

Kurt-Jones, Evelyn
first name: Evelyn
last name: Kurt-Jones
full name: Evelyn A Kurt-Jones PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 96
person in primary position: Professor
type: Agent
type: Person
Post Docs: We are seeking a post-doctoral fellow to study toll/interleukin 1 receptors and their role in inflammatory disease pathogenesis using human cells and mouse models. Candidates should have a Ph.D. or M.D. degree, or have completed degree requirements. Experience in immunology, molecular biology and/or biochemistry and publication of papers in the areas of cytokine biology, receptor biochemistry and/or cell signaling required.
Rotation Projects: Potential Rotation Projects Expression of Toll-like receptors: Patterns of TLR expression in normal cells. Control of TLR receptor expression by environmental factors and cytokines. TLR expression in diseased tissues. Role of TLRs in disease pathogenesis: Use of knockout and genetically defined animals to study the role of TLRs in the control of bacterial or viral diseases. Structure-function studies of TLR signaling: Assessing the signaling activity of wild type and mutant TLRs (altered by site-directed mutageneis) using transient transfection and luciferase reporter gene analysis.
preferred title: Professor

Guertin, David
first name: David
last name: Guertin
Twitter: https://profiles.umassmed.edu/profile/28867128
full name: David A Guertin PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
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Person ID: 99
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr.Guertin for additional details.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866529

Anesthesiology and Perioperative Medicine
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Research
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Friedmann, Peter
first name: Peter
last name: Friedmann
full name: Peter D Friedmann MD, MPH, DFASAM, FACP
has faculty rank: Professor
latitude: 42.10873680000000
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person in primary position: Professor
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preferred title: Professor

UMass Chan – Baystate Regional Campus
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https://profiles.umassmed.edu/profile/16237428
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Fergus Clydesdale Endowed Chair
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Wang, Bo
first name: Bo
last name: Wang
full name: Bo Wang PhD
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ADJUNCT ASSOCIATE PROFESSOR
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ADJUNCT PROFESSOR
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Gurwitz, Jerry
first name: Jerry
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Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
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Nguyen, Huy
first name: Huy
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full name: Huy Nguyen MD, PhD
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person in primary position: Adjunct Associate Professor
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webpage: https://profiles.umassmed.edu/profile/53696179
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Professor
is primary position: true
position in department: Population and Quantitative Health Sciences
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Medicine
position in division: Health System Science
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Molecular, Cell and Cancer Biology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
is primary position: true
position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Professor
is primary position: true
position in department: Program in Molecular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
is primary position: true
position in department: Medicine
position in division: Infectious Diseases
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Medicine
position in division: Infectious Diseases
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Vyas, Jatin
first name: Jatin
last name: Vyas
full name: Jatin Mahesh Vyas MD, PhD
has faculty rank: Professor
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 10248498
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor