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Thompson, Paul
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Zhu, Lihua
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Baehrecke, Eric
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Brown, Robert
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Summary: Dr. Brown’s laboratory has focused on the identification of gene defects that elucidate the molecular pathogenesis of selected neuromuscular diseases including amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease), muscular dystrophy, adrenoleukodystrophy, hereditary neuropathy and hyperkalemic periodic paralysis.
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Gao, Fen-Biao
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Rotation Projects: Project 1: Dervelop RNA-based therapies for frontotemporal dementia (FTD) and related disroders. Project 2: Study pathogenic mechanisms of FTD and related disorders in mouse models.
Summary: Our lab uses a combination of molecular, cellular, genetic, and behavioral approaches to further dissect the pathogenic mechanisms of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis with a focus on mutant CHMP2B, progranulin and C9ORF72. We will identify common underlying pathways as potential targets for therapeutic interventions.
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Futai, Kensuke
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Post Docs: Postdoctoral Position Available A postdoctoral position is available to study in this laboratory. Contact Kensuke Futai for additional details.
Rotation Projects: Rotation Projects The Futai laboratory seeks highly motivated graduate students who have interest in the roles of risk genes of neuropsychiatric diseases, such as autism and schizophrenia, on neuronal function.Rotation students will typically work side-by-side with Kenny Futai or Postdoctoral Fellows, and give one laboratory meeting presentation at the conclusion of their rotation project. Rotation projects The roles of the risk genes of neuropsychiatric diseases on neuronal structure and synaptic function The roles of the scaffold molecules in synapse maturation, synaptic transmission and synaptic plasticity Characterization of gultamate receptors which express in interneruon
preferred title: Associate Professor

Trivedi, Chinmay
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Rotation Projects: Rotation Projects: Please contact Chinmay Trivedi (chinmay.trivedi@umassmed.edu) for information regarding potential rotation projects (for details - research performed by graduate students in the trivedi lab: The Journal of Clinical Investigation, Science Advances, Journal of Experimental Medicine, JCI Insight, ATVB, Human Molecular Genetics, Journal of Biological Chemistry). We will develop a specific rotation project based on student's interest, background, and goals of the rotation. Students can rotate either for a half- or full-semester.
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Luban, Jeremy
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Post Docs: PostDoc Position available
Rotation Projects: Lab rotation position is available
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Fitzgerald, Katherine
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Corvera, Silvia
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Endowed Chair Honorary Title: Endowed Chair in Diabetes Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Corvera for additional details.
Rotation Projects: Rotation Projects Our rotation projects are in the area of diabetes and obesity, and we are interested in basic mechanisms of cell proliferation, differentiation and communication. Diabetes is highly correlated with obesity, but why obesity causes disease in some humans and not others is not understood. Amazingly, we still don’t understand how adipose tissue grows in human adults. A better understanding of this fascinating process can give us insight into basic mechanisms of cell growth, differentiation and communication, as well as mechanisms of disease, not only diabetes but also cancer and developmental defects. During your rotation, you will work on an important piece of a larger project, that has a well-defined outcome. Thus, your successful completion of the rotation project will allow you to be included at the time of publication of the work. Project 1: Adipose tissue is not only formed by adipocytes, but by other cells such as endothelial, mural and immune cells. Also, there are multiple kinds of adipocytes with different functions. We have recently developed conditions to develop adipose tissue from humans in-vitro (adipose tissue “organoids”). From this tissue we have been able to separated single cells, and find that they grow into different kinds of clones. We are now conducting RNAseq on >300 of those clones, to determine how many cell types exist in human adipose tissue, and what their roles are. In this rotation, you will be able to analyze RNAseq data to define what genes characterize these cells, and you will use virus transduction to create immortalized cells for further study. Project 2: Adipose tissue has many functions besides storing and releasing lipids. It also has to coordinate metabolism in the whole body. We have found that human “beige” adipose tissue, which is found in people who are metabolically healthy, expresses genes for secreted factors that communicate with the immune system and the brain. These include IL-33 and enkephalins. In t…
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Shultz, Leonard
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Marinus, Martin
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Rotation Projects: Project 1 Investigate the lethal expression of P35 in dam lysogens. Plus inducer No inducer Lysogenic cultures of p35/dam (top) and p35/wildtype (bottom) were diluted and aliquots spotted on media with and without inducer.
preferred title: Professor Emeritus

Munson, Mary
first name: Mary
last name: Munson
full name: Mary Munson PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 312
person in primary position: Professor
type: Agent
type: Person
Rotation Projects: Potential Rotation Projects <p >Research in the Munson lab is focused on biochemical/biophysical and cell biological characterization of proteins in the exocyst complex. Potential rotation projects include the following: Cloning of various exocyst protein domains and point mutations. These will be expressed in E. coli for biochemical/structural studies, and their functions tested in yeast. Protein expression and purification. Develop purification strategies for several exocyst proteins and their domains, using chromatography methods such as ion exchange and gel filtration (Fig. 2). Characterization of the purified exocyst proteins. Protein structure, stability, oligomerization state and protein:protein interactions will be monitored by such techniques as circular dichroism, analytical ultracentrifugation and gel filtration (Fig. 3). Crystallography. We have determined the structure of the C-terminal domain of Sec6p (Fig. 4). Crystallization trials ofotherexocyst proteins and their domains are in progress. Design and test functional exocyst mutants in yeast. Mutants will be characterized using a variety of biochemical, cell biological, and microscopic techniques. Identify novel regulators of yeast exocytosis using a genetic screen. Mutants created in these screens are currently being tested and identified (Fig. 5). Their role in exocytosis will be explored <p >
preferred title: Professor

Davis, Roger
first name: Roger
last name: Davis
full name: Roger J Davis PhD, FRS
has faculty rank: Chair And Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 3130
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866429

Kelch, Brian
first name: Brian
last name: Kelch
full name: Brian Anthony Kelch PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
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Person ID: 3279
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Emerson, Charles
first name: Charles
last name: Emerson
full name: Charles P Emerson Jr. PhD
has faculty rank: Professor
latitude: 42.27719870000000
longitude: -71.75921810000000
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Person ID: 3371
person in primary position: Professor
type: Agent
type: Person
Lab URL: https://www.umassmed.edu/emersonlab
Summary: The Emerson lab investigates skeletal muscle development and disease. Research has focused on defining transcriptional networks and signaling pathways that control the specification and differentiation of skeletal muscle progenitors in the developing embryo.
preferred title: Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 50.70274210000000
longitude: 7.10034010000000
Person ID: 3432
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Verma, Ashish
first name: Ashish
last name: Verma
full name: Ashish Verma MD, MRCP, FACP, FASN, FRCP
has faculty rank: Assistant Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
Person ID: 3588
person in primary position: Assistant Professor
type: Agent
type: Person
preferred title: Assistant Professor

Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27636250000000
longitude: -71.76564740000000
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Person ID: 36
person in primary position: Adjunct Professor
type: Agent
type: Person
Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Lian, Jane
first name: Jane
last name: Lian
full name: Jane B Lian PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27723620000000
longitude: -71.76070940000000
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Person ID: 370
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Gierasch, Lila
first name: Lila
last name: Gierasch
full name: Lila M Gierasch Ph.D.
has faculty rank: Distinguished Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3705
person in primary position: Distinguished Professor
type: Agent
type: Person
preferred title: Distinguished Professor

Rotello, Vincent
first name: Vincent
last name: Rotello
full name: Vincent Rotello PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3741
person in primary position: Department Head
type: Agent
type: Person
preferred title: Department Head

McClements, David
first name: David
last name: McClements
full name: David J McClements B.S., Ph.D.
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3760
person in primary position: Fergus Clydesdale Endowed Chair
type: Agent
type: Person
preferred title: Fergus Clydesdale Endowed Chair

Pederson, Thoru
first name: Thoru
last name: Pederson
full name: Thoru Pederson PhD
has faculty rank: Professor Emeritus
latitude: 42.28050130000000
longitude: -71.76534550000000
Person ID: 379
person in primary position: Professor Emeritus
type: Agent
type: Person
Endowed Chair Honorary Title: Vitold Arnett Professor of Cell Biology
Rotation Projects: Background for Student Rotation Projects <p >See Politz, Hogan and Pederson (2009) and Politz et al. (2005) in the above list. The novel microRNA work may be the most suitable for student rotations. Potential Rotation Projects <p >Are the nucleolar microRNAs pri-, pre- or mature? <p >Are they complexed with other nucleolar RNAs? <p >Do the cell cycle related proteins in the nucleolus exist as heterotypic complexes? <p >Does the nucleolus of human embryonic stem cells also share these features (which we have so far looked for, and found, only in transformed human cell lines)? <p >Can vanadium tagging be used to detect specific proteins by electron microscopy, perhaps exceeding the limitations of immuno-EM?
preferred title: Professor Emeritus

Rogaev, Evgeny
first name: Evgeny
last name: Rogaev
full name: Evgeny I Rogaev PhD
has faculty rank: Professor
latitude: 42.27380970000000
longitude: -71.76834340000000
Person ID: 39
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rogaev for additional details.
preferred title: Professor

Zamore, Phillip
first name: Phillip
last name: Zamore
full name: Phillip D Zamore PhD
has faculty rank: Chair And Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
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Person ID: 418
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Gretchen Stone Cook Chair in Biomedical Sciences
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Zamore for additional details
Rotation Projects: Potential Rotation Projects Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866555
webpage: https://profiles.umassmed.edu/profile/28866537
webpage: https://profiles.umassmed.edu/profile/28866541

Aronin, Neil
first name: Neil
last name: Aronin
full name: Neil Aronin MD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 490
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Higgins Family Professor in Neuroscience
Rotation Projects: Potential Rotation Projects Project #1: Molecular Mechanisms in the Pathogenesis of Neurodegenerative Disease. The student can select projects emphasizing either molecular mechanisms of huntingtin in trafficking in neurons or receptor stimulated effects on gene expression in neurons. Techniques include: Generation of fusion proteins, raising antisera Preparation of organelles Immunocytochemistry, light microscopy and electron microscopy Immunoprecipitation methods PCR Protein separation techniques, gel electrophoresis, immunoblotting Autoradiography
preferred title: Professor

Imbalzano, Anthony
first name: Anthony
last name: Imbalzano
full name: Anthony N Imbalzano PhD
has faculty rank: Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
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Person ID: 507
person in primary position: Professor
type: Agent
type: Person
Post Docs: Please contact Dr. Imbalzano to discuss the possibility of a postdoctoral training.See lab research interests and publications for recent topics of research. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
Rotation Projects: Please contact Dr. Imbalzano to discuss the possibility of a rotation project. Rotation projects are generally based on current work and tailored to the interests of the student. See lab research interests and publications for recent topics. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
preferred title: Professor

Schiffer, Celia
first name: Celia
last name: Schiffer
Featured Videos: https://profiles.umassmed.edu/profile/28867214
full name: Celia A Schiffer PhD
has faculty rank: Chair And Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
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Person ID: 558
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Arthur F. and Helen P. Koskinas Professor in Biochemistry and Molecular Biotechnology
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866505

McCollum, Dannel
first name: Dannel
last name: McCollum
full name: Dannel McCollum PhD
has faculty rank: Professor
latitude: 42.27491030000000
longitude: -71.76424060000000
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Person ID: 561
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. McCollum for additional details.
Rotation Projects: Rotation Projects Analog sensitive LATS kinase: The goal of this project is to use CRISPR based genome modification to make mutations in the endogenous LATS kinase that cause it to be inhibited by a synthetic ATP analog. This will allow LATS kinase activity to be turned on and off using the ATP analog. The analog sensitive cell line will be a valuable tool for studying Hippo pathway responses to various stimuli and will be used to test whether dephosphorylation of LATS substrates is an important regulatory mechanism. This project will also set the stage for future experiments to create mice that have analog sensitive versions of LATS. These mice will be used to test whether LATS inhibition is a viable treatment for regenerative therapies for the heart, gut, pancreas and other organs. TRIP6 and Angiomotin interacting proteins: We know that cells monitor their mechanical environment by sensing F-actin levels and by measuring tension at cell-cell junctions. We have identified angiomotins as sensors for F-actin and the TRIP6 protein as part of a tension sensor at cell-cell junctions. However, to understand how these sensors work, we need know the network of proteins that they each interact with, and how those networks change in response to mechanical perturbations. To do this we will fuse each sensor to the promiscuous biotin ligase protein BirA, and express the fusion proteins in cells under various conditions. The biotin ligase will label proteins in close proximity with biotin. Labeled proteins will be purified and analyzed by mass spectrometry, and the spectrum of interacting partners under different conditions will be compared.
preferred title: Professor

Ross, Alonzo
first name: Alonzo
last name: Ross
full name: Alonzo H Ross PhD
has faculty rank: Professor Emeritus
latitude: 42.27636250000000
longitude: -71.76564740000000
Person ID: 584
person in primary position: Professor Emeritus
type: Agent
type: Person
Rotation Projects: Rotation Projects Potential Rotation Projects Allostericregulation of PTEN using biophysical techniques. Analysis of PTEN structure by NMR. Therapies directed against cancer stem cells for human glioblastomas. Signaling directed therapies for meningioma brain tumors. <p > <p >
preferred title: Professor Emeritus

Wolfe, Scot
first name: Scot
last name: Wolfe
full name: Scot Wolfe PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 595
person in primary position: Professor
type: Agent
type: Person
Post Docs: Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Rotation Projects: Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
preferred title: Professor

Lambright, David
first name: David
last name: Lambright
full name: David Lambright PhD
has faculty rank: Professor
latitude: 42.27932700000000
longitude: -71.76549170000000
Person ID: 604
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Lambright for additional details.
Rotation Projects: Lab Rotations <p >Our lab takes an interdisciplinary approach to the study of fundamental problems in cell biology, signal transduction and membrane trafficking. Rotation projects are available in any of the areas of interest to the lab. Projects are tailored to the individual interests of the students and often involve a combination of molecular, biochemical, biophysical, structural and/or cell based analyses to investigate signaling and trafficking mechanisms. <p >
preferred title: Professor

Budnik, Vivian
first name: Vivian
last name: Budnik
full name: Vivian Budnik PhD
has faculty rank: Professor And Chair Emeritus
latitude: 42.27737440000000
longitude: -71.76346650000000
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Person ID: 610
person in primary position: Professor and Chair Emeritus
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Budnik for additional details.
preferred title: Professor and Chair Emeritus

Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
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Person ID: 612
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
preferred title: Professor

Pazour, Gregory
first name: Gregory
last name: Pazour
full name: Gregory J Pazour PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 621
person in primary position: Professor
type: Agent
type: Person
Rotation Projects: Potential Rotation Projects Rotation projects in my laboratory will involve questions of how cilia are assembled and the function these organelles play in mammals. Projects vary depending on ongoing work in the laboratory and interests of the rotation student. Rotations in my laboratory can give students exposure to a range of techniques from mouse breeding and histological analysis of mouse tissues to mammalian cell culture and other cell biological techniques.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/41661165

Peterson, Craig
first name: Craig
last name: Peterson
full name: Craig L Peterson PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
Person ID: 633
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Elisabeth Chair I
preferred title: Professor

Dekker, Job
first name: Job
last name: Dekker
full name: Job Dekker PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 759
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Joseph J. Byrne Chair in Biomedical Research
Rotation Projects: ? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866525
webpage: https://profiles.umassmed.edu/profile/28866572

Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 78
person in primary position: Professor Emeritus
type: Agent
type: Person
preferred title: Professor Emeritus

Bach, Ingolf
first name: Ingolf
last name: Bach
full name: Ingolf M Bach PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 905
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Bach for additional details.
Rotation Projects: Rotation Projects For rotation projects, please inquire with Dr. Bach.
preferred title: Professor

Bolon, Daniel
first name: Daniel
last name: Bolon
full name: Daniel N Bolon PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
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Person ID: 948
person in primary position: Professor
type: Agent
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Rotation Projects: Potential Rotation Projects <p >Our laboratory combines genetic and biochemical approaches to investigate the molecular underpinnings of adaptation. Potential rotation projects are available in two general (and partially overlapping) areas: exploring fitness landscapes through systematic approaches and investigating the molecular mechanism of the Hsp90 chaperone in signal transduction. Please contact the lab to discuss specific rotation projects in more detail.
preferred title: Professor

Zhang, Hong
first name: Hong
last name: Zhang
full name: Hong Zhang PhD
has faculty rank: Associate Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 978
person in primary position: Associate Professor
type: Agent
type: Person
Post Docs: Postdoctoral Position Available A postdoctoral fellow position is available in the Zhang laboratory. Areas of study include the molecular mechanisms of senescence and its functions in cancer and aging. Both cell culture and mouse models are used. A Ph.D. in molecular and cellular biology, genetics, or a related field is required. Prior experience in cell culture and mouse genetics is desirable. Please send curriculum vitae to Dr. Zhang (hong.zhang@umassmed.edu).
Rotation Projects: Rotation Opportunities Germinal center response in lymphomagenesis Smurf2's role in autoimmunity and its link with lymphoma development Hematopoietic stem cell quiescence, senescence and aging Genetic screen of senescence regulators using genome-wide shRNA-mediated gene silencing Characterization of substrate specificity of HECT family E3 ligases
preferred title: Associate Professor

UMass Chan – Baystate Regional Campus
type: Organization

Engelman, Daniel
first name: Daniel
last name: Engelman
full name: Daniel Engelman MD
has faculty rank: Professor
latitude: 42.12076620000000
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Person ID: 4596
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Singh, Sonal
first name: Sonal
last name: Singh
full name: Sonal Singh MD, MPH
has faculty rank: Associate Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 4649
person in primary position: Associate Professor
type: Agent
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preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866602

Distinguished Professor
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HR job title: Distinguished Professor
position in organization: University of Massachusetts Amherst

Department Head
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Fergus Clydesdale Endowed Chair
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HR job title: Fergus Clydesdale Endowed Chair
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ADJUNCT PROFESSOR
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Ralto, Kenneth
first name: Kenneth
last name: Ralto
full name: Kenneth Michael Ralto MD
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 5324
person in primary position: Associate Professor
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preferred title: Associate Professor

Population and Quantitative Health Sciences
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Orzalli, Megan
first name: Megan
last name: Orzalli
full name: Megan Horn Orzalli PhD
has faculty rank: Associate Professor
latitude: 42.27491030000000
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Person ID: 5640
person in primary position: Associate Professor
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preferred title: Associate Professor

Shen, Kuang
first name: Kuang
last name: Shen
full name: Kuang Shen PhD
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 5693
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866636

Ross, Jonathan
first name: Jonathan
last name: Ross
full name: Jonathan J Ross MD, PhD
has faculty rank: Assistant Professor
latitude: 42.12294230000000
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Person ID: 5762
person in primary position: Assistant Professor
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preferred title: Assistant Professor

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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Assistant Professor
is primary position: true
position in department: Systems Biology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Program in Molecular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
is primary position: true
position in department: Medicine
position in division: Renal Medicine
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
sort order: 3
type: Faculty Rank

Professor Emeritus
sort order: 8
type: Faculty Rank

Professor And Chair Emeritus
sort order: 7
type: Faculty Rank

Assistant Professor
sort order: 13
type: Faculty Rank

Associate Professor
sort order: 10
type: Faculty Rank

Chair And Professor
sort order: 4
type: Faculty Rank

Distinguished Professor
sort order: 6
type: Faculty Rank

Professor
is primary position: true
position in department: Medicine
position in division: Endocrinology & Diabetes
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Psychiatry and Behavioral Sciences
type: Department
type: Organization

Professor
is primary position: true
position in department: Psychiatry and Behavioral Sciences
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
is primary position: true
position in department: Neurobiology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Neurology
position in division: Neuromuscular
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Assistant Professor
is primary position: true
position in department: Emergency Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Medicine
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Chair and Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Medicine
position in division: Endocrinology & Diabetes
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Molecular, Cell and Cancer Biology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Indes, Jeffrey
first name: Jeffrey
last name: Indes
full name: Jeffrey E Indes MD, FACS
has faculty rank: Professor
Person ID: 10248490
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Associate Professor
is primary position: true
position in department: Medicine at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor Emeritus
is primary position: true
position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Associate Professor
is primary position: true
position in department: Family Medicine and Community Health
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Hu, Yao-Wen
first name: Yao-Wen
last name: Hu
full name: Yao-Wen Eliot Hu MD
has faculty rank: Associate Professor
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 10248512
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Pediatric Gene Development
type: Division
type: Organization

Associate Professor
is primary position: true
position in department: Pediatrics
position in division: Pediatric Gene Development
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor and Chair Emeritus
is primary position: true
position in department: Neurobiology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor and Chair Emeritus
position in organization: UMass Chan Medical School