Johnnie Ray Cox Term Chair in Biomedical Research
Cutler Chair in Vascular and Endovascular Surgery
Potential Rotation Projects Proteostasis regulators, HSF1, HSP70 and HSP90 in liver disease: Determine the expression and function in different cell types of the liver during acute and chronic liver injury using in vivo and in vitro models. Subsequently, we will test the relevance of the expression of these proteins in activation of intracellular signaling molecules involved in induction of fatty liver, inflammation and fibrosis. Role of chemokines in liver disease: CC-chemokines particularly CCL2/MCP-1, is significantly increased in serum as well as in the liver parenchyma in patients with alcoholic hepatitis. We test the role of MCP-1 in induction of fatty acid synthesis or metabolism and inflammation in the alcoholic liver. Our studies will also investigate the role of MCP-1 directed migration of immune cells in the liver contributing to injury.
Fellowship in Minimally Invasive Surgery performed at The University of Massachusetts Medical School 2001-2003.
Joseph M. Streeter and Mary Streeter DeFeudis Chair in Surgery
Brian Silver MD, FRCPC, FAHA, FAAN, FANA
Population and Quantitative Health Sciences
Healthcare Delivery and Population Sciences at UMass Chan - Baystate
Obstetrics and Gynecology at UMass Chan - Baystate
Joseph D. Early Chair in Biomedical Research
Advisory links alcohol consumption to cancers: Here's how Worcester feels about the report