Mosa Alhamami, Ph.D., MCCPM is a board-certified Medical Physicist and Assistant Professor in the Department of Radiology at UMass Chan-Lahey. Prior to his current position, he practised as a clinical medical physicist in Hartford, CT, and Honolulu, HI, and was previously a resident in diagnostic imaging physics at the Department of Radiology & Imaging Sciences, Indiana University (IU) School of Medicine. He earned his Ph.D. in Imaging Biophysics & Biomedical Engineering from the University of Toronto, where he held a prestigious Natural Sciences & Engineering Research Council of Canada (NSERC) Alexander Graham Bell Canada Graduate Scholarship. He also holds an M.Sc. in Biomedical Physics and B.Sc. (With Distinction) in Medical Physics, both from Toronto Metropolitan University (formerly Ryerson University). Dr. Alhamami has a strong interest in clinical medical physics as well as research and education. Clinically, Dr. Alhamami provides diagnostic medical physics support in MRI, CT, mammography (2D & 3D), stereotactic breast biopsy, ultrasound, radiography and fluoroscopy. He is also involved with some nuclear medicine/PET quality assurance work. As a researcher, Dr. Alhamami's expertise is in contrast-enhanced MRI techniques for cellular imaging of cancer and quantitative MRI measurements for tissue characterization. Specifically, he is very interested in the investigation of novel contrast media for cancer imaging, molecular and cellular MRI, and multifunctional drug delivery nano-systems for cancer imaging and therapy. The findings of his doctoral work at the University of Toronto have provided a novel gadolinium-free approach to sensitively detect multiple clinical subtypes of breast cancer cells, thereby enabling early detection and characterization of breast cancers. Previously, Dr. Alhamami was involved in the development of ultrasonic and photoacoustic methods that enabled the detection of high-intensity focused ultrasound (HIFU) thermal treatments in biologic tissues, where he studied bio-heat transfer and acoustic wave propagation in tissues and conducted an in-depth study of light photon-tissue interactions, performing novel optical spectroscopy measurements on the induced thermal lesions in biologic tissues. Discovering state-of-the-art imaging methods that enable the detection of HIFU treatments noninvasively is a strong area of his research interest. In addition to his clinical and scholarly activities, Dr. Alhamami has a strong commitment to excellence in teaching, training, and learning. He has previously held appointments as an Instructor and Teaching Assistant in 11 undergraduate courses at the University of Toronto and Ryerson University, where he also mentored and supervised research assistants and undergraduate students in research laboratories. As an educator, he trained students from various backgrounds, including biomedical engineering, mechanical / industrial engineering, pharmacy, and physics. Recently, he was involved in designing and delivering medical imaging physics lectures to diagnostic and interventional radiology resident physicians at IU School of Medicine. Mosa.Alhamami@umassmed.edu
Toronto Metropolitan University, Medical Physics
Toronto Metropolitan University, Biomedical Physics
University of Toronto, Imaging Biophysics & Biomedica
Alhamami M, Cheng W, Lyu Y, Allen C, Zhang XA, Cheng HL
Alhamami M, Cheng W, Lyu Y, Allen C, Zhang XA, Cheng HL. Manganese-porphyrin-enhanced MRI for the detection of cancer cells: A quantitative in vitro investigation with multiple clinical subtypes of breast cancer. PLoS One. 2018; 13(5):e0196998.
Manganese-porphyrin-enhanced MRI for the detection of cancer cells: A quantitative in vitro investigation with multiple clinical subtypes of breast cancer.
Ganesh T, Mokhtari RB, Alhamami M, Yeger H, Cheng HL
Journal of magnetic resonance imaging : JMRI
Ganesh T, Mokhtari RB, Alhamami M, Yeger H, Cheng HL. Manganese-enhanced MRI of minimally gadolinium-enhancing breast tumors. J Magn Reson Imaging. 2015 Mar; 41(3):806-13.
Manganese-enhanced MRI of minimally gadolinium-enhancing breast tumors.
Alhamami M, Kolios MC, Tavakkoli J. Photoacoustic detection and optical spectroscopy of high-intensity focused ultrasound-induced thermal lesions in biologic tissue. Med Phys. 2014 May; 41(5):053502.
Photoacoustic detection and optical spectroscopy of high-intensity focused ultrasound-induced thermal lesions in biologic tissue.
Alhamami M, Daye D. Editorial for "In Vivo MRI Tracking of Polyurethane Hydrogel Degradation In Situ Using a Manganese Porphyrin Contrast Agent". J Magn Reson Imaging. 2023 10; 58(4):1151-1152.
Editorial for "In Vivo MRI Tracking of Polyurethane Hydrogel Degradation In Situ Using a Manganese Porphyrin Contrast Agent".
Veronesi MC, Alhamami M, Miedema SB, Yun Y, Ruiz-Cardozo M, Vannier MW
American journal of nuclear medicine and molecular imaging
Veronesi MC, Alhamami M, Miedema SB, Yun Y, Ruiz-Cardozo M, Vannier MW. Imaging of intranasal drug delivery to the brain. Am J Nucl Med Mol Imaging. 2020; 10(1):1-31.
Imaging of intranasal drug delivery to the brain.
Alhamami M, Bayat Mokhtari R, Ganesh T, Tchouala Nofiele J, Yeger H, Margaret Cheng HL
Alhamami M, Bayat Mokhtari R, Ganesh T, Tchouala Nofiele J, Yeger H, Margaret Cheng HL. Manganese-enhanced magnetic resonance imaging for early detection and characterization of breast cancers. Mol Imaging. 2014; 13.
Manganese-enhanced magnetic resonance imaging for early detection and characterization of breast cancers.
NSERC Alexander Graham Bell Canada Graduate Scholarship – Doctoral (NSERC CGS - D3)
University of Toronto Nominee for the Ontario Women’s Health Scholars Award
University of Toronto Nominee for the Vanier Canada Graduate Scholarship
University of Toronto Doctoral Fellowships
Best research article (MSc paper), Faculty of Science
Top-ranked graduate student graduating in Fall 2013, Dept. of Physics
Travel Award to the 2012 Canadian Association of Physicists (CAP) Congress
Travel Award to the 2011 Canadian Undergraduate Physics Conference
Science Mentorship & Leadership Certificate Award
Institute of Medical Science PhD Entrance Award (declined), Faculty of Medicine
Alhamami M, Tran S, Tavakkoli J. Effects of High-Intensity Focused Ultrasound with Different Acoustic Doses on Neural Tissues in Vitro. Canadian Acoustics. 2011; 39(3):40-41.
Effects of High-Intensity Focused Ultrasound with Different Acoustic Doses on Neural Tissues in Vitro
Milman R, Bevins NB, Alhamami M, Busse N, Dohatcu A, Hulme KW, Jafari ME, LaFontaine SM, Nawfel RD, Nelson JS, Russ MK, Silosky M, Wait JM
Journal of applied clinical medical physics
Milman R, Bevins NB, Alhamami M, Busse N, Dohatcu A, Hulme KW, Jafari ME, LaFontaine SM, Nawfel RD, Nelson JS, Russ MK, Silosky M, Wait JM. AAPM Medical Physics Practice Guideline MPPG 17.a: Quality management for mammography review workstation displays. J Appl Clin Med Phys. 2025 Apr; 26(4):e14625.
AAPM Medical Physics Practice Guideline MPPG 17.a: Quality management for mammography review workstation displays.
Raman AP, Kotlarz PL, Giff AE, Goundry KA, Laeseke P, Koepsel EMK, Alhamami M, Daye D
Raman AP, Kotlarz PL, Giff AE, Goundry KA, Laeseke P, Koepsel EMK, Alhamami M, Daye D. Breaking Barriers with Sound: The Implementation of Histotripsy in Cancer. Cancers (Basel). 2025 Aug 01; 17(15).
Breaking Barriers with Sound: The Implementation of Histotripsy in Cancer.