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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
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https://profiles.umassmed.edu/profile/88314388
publication date: 2025
type: URLLink
label: https://www.onclive.com/view/ihc-testing-may-enable-expedited-identification-of-tp53-mutant-mds-and-aml
link anchor text: OncLive with Dr. Patel and Dr. Gerber: p53 Immunohistochemistry

https://profiles.umassmed.edu/profile/89429665
publication date: 2025
type: URLLink
label: https://www.onclive.com/view/dr-patel-on-the-p53-ihc-positivity-as-potential-surrogate-for-multi-hit-tp53-mutations-in-mds-and-aml
link anchor text: Early Identification of TP53-Mutant MDS and AML Using p53 Immunostaining

https://profiles.umassmed.edu/profile/89429727
publication date: 2023
type: URLLink
label: https://journals.lww.com/oncology-times/blog/onlinefirst/pages/post.aspx
link anchor text: Point-of-Care p53 IHC Unveils TP53-Mutant MDS/AML

https://profiles.umassmed.edu/profile/89429786
publication date: 2025
type: URLLink
label: https://trial.medpath.com/news/61960d9f316e3daa/ihc-testing-enables-rapid-tp53-mutation-detection-in
link anchor text: IHC Enables Rapid Identification of TP53-Mutant MDS/AML

Assistant Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Rieger-Christ, Kimberly
first name: Kimberly
last name: Rieger-Christ
full name: Kimberly M Rieger-Christ PhD
has faculty rank: Assistant Professor
Person ID: 10248582
person in primary position: Assistant Professor
type: Agent
type: Person
preferred title: Assistant Professor

Chair and Associate Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Chair and Associate Professor
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/95558627
publication date: 2025
type: URLLink
label: https://ashpublications.org/ashclinicalnews/news/8743/p53-IHC-Testing-May-Be-Reliable-Surrogate-for
link anchor text: ASH Clinical News: p53 Immunohistochemistry for TP53-Mutant MDS/AML

Adjunct Assistant Professor
is primary position: true
position in department: Pediatrics
position in division: Pediatric Research
sort order: 1
type: Position
HR job title: Adjunct Assistant Professor
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/99769701
publication date: 2025
type: URLLink
label: https://journals.lww.com/oncology-times/fulltext/2025/11000/immunostaining_offers_shortcut_to_detect_high_risk.20.aspx
link anchor text: p53 Immunostain in TP53-Mutant MDS and AML

Associate Professor
is primary position: true
position in department: Surgery
position in division: Cardio Thoracic Surgery
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School