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Sluder, Greenfield
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Rotation Projects: Potential Rotation Projects We favor having students work independently on defined projects that have promise of completion during the study period. Project #1: Use a frog egg extract that supports multiple rounds of centrosome duplication in vitro to investigate the role of various high interest kinases in the control of centrosome duplication. Also, we can use these extracts to further investigate how various other proteins interact with the centrosome to influence its duplication. Hinchcliffe, E.H., C. Li, E.A. Thompson, J.L. Maller and G. Sluder. 1999. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extract. Science 283:851-854. Project #2: Use microsurgery and immunofluorescence on BSC-1 cells to further investigate how centrioles influence the interphase progression of the cell cycle. Hinchcliffe, E.H., F.J. Miller, M. Cham, A. Khodjakov and G. Sluder. 2001. Requirement of a centrosomal activity for cell cycle progression through G1 into S phase. Science 291: 1547-1550.
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Chueh, Juyu
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Soller, Babs
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Karellas, Andrew
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Vedantham, Srinivasan
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Craig, Roger
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Rotation Projects: Potential Rotation Projects Project #1: Lipid-Layer Protein Crystallization for Electron Microscopy.While individual protein molecules can be readily visualized by EM, structural information is greatly enhanced if the molecules can by crystallized into 2-dimensional ordered arrays. Methods for achieving this are well established, making use of lipid monolayers at an air-water interface. Follow literature methods to crystallize "standard" proteins using the lipid-layer method. Observe results by electron microscopy following negative staining. If time permits, carry out preliminary image processing of micrographs and/or crystallization of unknown proteins. Techniques to be learned: lipid layer crystallization methods; grid preparation; use of electron microscope; image processing.
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Goldberg, Robert
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Shaw, Leslie
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Bogdanov, Alexei
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Gounis, Matthew
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McManus, David
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Parker, Matthew
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Lindsay, Clifford
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Anesthesiology and Perioperative Medicine
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UMass Chan – Baystate Regional Campus
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Cadavid, Diego
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Gurwitz, Jerry
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Ughi, Giovanni
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Post Docs: Harvard Medical School and Massachusetts General Hospital, Boston Postdoctoral Training Biomedical Optics and Translational Medicine
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Grigorieff, Nikolaus
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Population and Quantitative Health Sciences
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Erbay, Sami
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Shazeeb, Mohammed
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Bankier, Alexander
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Schlaug, Gottfried
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Auer, Benjamin
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Shipley, Rebecca
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King, Robert
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Kalluri, Kesava
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Yemini, Eviatar
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Lab URL: https://www.yeminilab.org
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Lin, Honghuang
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https://www.umassmed.edu/globalassets/radiology/documents/King-Graduate Student-Training-UpTo-2020.pdf
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Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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Neurology at UMass Chan - Baystate
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Adjunct Assistant Professor
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Adjunct Associate Professor
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Professor
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Professor Emeritus
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Instructor
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Assistant Professor
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Assistant Professor
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Saranathan, Manojkumar
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https://profiles.umassmed.edu/profile/31148323
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Vachha, Behroze
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Singhal, Amit
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Genomics and Computational Biology
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Medicine at UMass Chan - Lahey
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Radiology at UMass Chan - Lahey
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Cardio Thoracic Radiology
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Health System Science
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Infectious Diseases
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Neurointerventional Radiology
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Pulmonary Medicine
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Professor
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Stroke and Vascular Neurology
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Professor
is primary position: true
position in department: Radiology
position in division: Neuroradiology
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School