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Harrold, Leslie
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Hayman, Laura
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Simons, Jessica
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Bertone-Johnson, Elizabeth
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Crawford, Sybil
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Reed, George
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Rotation Projects: Additional information about lab rotations within the CPHR program can be found athttp://www.umassmed.edu/cphr/program/rotations.aspx
preferred title: Professor

Harris, John
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Person ID: 53
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Endowed Chair Honorary Title: Lambi and Sarah Adams Chair in Genetic Research
Rotation Projects: Rotations: Targeting the IFN-?-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking real-time autoreactive T cell migration and interactions within the skin: We are usin…
Rotation Projects: Rotations: Targeting the IFN-g-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking autoreactive T cell interactions within the skin: We are using fluorescently tagged C…
Summary: Interests: Vitiligo, autoimmunity, immunology, translational research
preferred title: Adjunct Professor

Rosal, Milagros
first name: Milagros
last name: Rosal
full name: Milagros Rosal PhD
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Person ID: 594
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Endowed Chair Honorary Title: Imoigele P. Aisiku, MD’97 Chair in Health Equity and Diversity
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webpage: https://profiles.umassmed.edu/profile/28866430

Levin, Nikki
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last name: Levin
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Person ID: 686
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Summary: Interests: Psoriasis, atopic dermatitis, acne vulgaris, perioral dermatitis, fungal infections, cutaneous malignancies, infectious diseases, medical education
preferred title: Professor

Lemon, Stephenie
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last name: Lemon
full name: Stephenie C Lemon PhD
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Person ID: 689
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Endowed Chair Honorary Title: Barbara Helen Smith Chair in Preventive & Behavioral Medicine
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webpage: https://profiles.umassmed.edu/profile/28866492

Kornfeld, Hardy
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last name: Kornfeld
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latitude: 42.27985300000000
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Person ID: 739
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preferred title: Professor

Goldberg, Robert
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last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
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Person ID: 78
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Belazarian, Leah
first name: Leah
last name: Belazarian
full name: Leah Belazarian MD
has faculty rank: Associate Professor
latitude: 42.28554670000000
longitude: -71.79046720000000
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Person ID: 785
person in primary position: Associate Professor
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Summary: Interests: Pediatric dermatology, psoriasis, genodermatoses, medical dermatology, inpatient dermatology
preferred title: Associate Professor

Sassetti, Christopher
first name: Christopher
last name: Sassetti
full name: Christopher M Sassetti PhD
has faculty rank: Professor
latitude: 42.27587600000000
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Person ID: 878
person in primary position: Professor
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Endowed Chair Honorary Title: Elisabeth Chair II
Lab URL: https://www.umassmed.edu/sassettilab/
Rotation Projects: Rotation Projects <p >We have identified a number of bacterial pathways that are required for bacterial viability or virulence. We are particularly interested in: Phosphosignaling systems that regulate cell wall synthesis Metabolic regulatory mechanisms that trigger the “dormancy” response observed during infection. <p >A variety of genetic, biochemical, and informatic methods will be used to define the functions of these genes and the role played by each during infection. <p >
Summary: Focus: Pathogenesis of tuberculosis
preferred title: Professor

Moser, Richard
first name: Richard
last name: Moser
full name: Richard P Moser MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 989
person in primary position: Professor
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McManus, David
first name: David
last name: McManus
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Person ID: 994
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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Szkwarko, Daria
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full name: Daria Lesia Szkwarko DO
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Person ID: 4254
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Research
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Friedmann, Peter
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full name: Peter D Friedmann MD, MPH, DFASAM, FACP
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Person ID: 4333
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UMass Chan – Baystate Regional Campus
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Dermatology
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Singh, Sonal
first name: Sonal
last name: Singh
full name: Sonal Singh MD, MPH
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 4649
person in primary position: Associate Professor
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webpage: https://profiles.umassmed.edu/profile/28866602

Associate Professor
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position in organization: University of Massachusetts Amherst

https://profiles.umassmed.edu/profile/16236512
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https://profiles.umassmed.edu/profile/16237425
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https://profiles.umassmed.edu/profile/16237431
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https://profiles.umassmed.edu/profile/16237479
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Lindenauer, Peter
first name: Peter
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Person ID: 4845
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Copeland, Laurel
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latitude: 42.34806320000000
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Person ID: 5070
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ADJUNCT ASSISTANT PROFESSOR
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ADJUNCT ASSOCIATE PROFESSOR
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ADJUNCT PROFESSOR
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Seddon, Johanna
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Gurwitz, Jerry
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Person ID: 5308
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Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
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Usmani, Saad
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Ophthalmology and Visual Sciences
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Population and Quantitative Health Sciences
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Neurological Surgery
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Bokhour, Barbara
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latitude: 42.27525000000000
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Person ID: 10246595
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Yonkers, Kimberly
first name: Kimberly
last name: Yonkers
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latitude: 42.27525000000000
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Person ID: 10246726
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Endowed Chair Honorary Title: Katz Family Chair in Psychiatry
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preferred title: Chair and Professor

Lin, Honghuang
first name: Honghuang
last name: Lin
full name: Honghuang Lin PhD
has faculty rank: Professor
latitude: 42.27525000000000
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https://profiles.umassmed.edu/profile/28866430
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link anchor text: UMass Worcester Prevention Research Center

https://profiles.umassmed.edu/profile/28866492
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link anchor text: Prevention Research Center at UMass Chan

https://profiles.umassmed.edu/profile/28866602
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https://profiles.umassmed.edu/profile/28867032
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Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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Medicine at UMass Chan - Baystate
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Adjunct Professor
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position in organization: UMass Chan Medical School

Adjunct Professor
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position in division: Preventive And Behavioral Medicine
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position in organization: UMass Chan Medical School

Adjunct Assistant Professor
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position in department: Emergency Medicine
position in division: Toxicology
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Instructor
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Adjunct Professor
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Adjunct Assistant Professor
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position in department: Dermatology
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position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Pediatrics
position in division: Community Pediatrics
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Associate Professor
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Associate Professor
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position in division: Rheumatology
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position in organization: UMass Chan Medical School

Adjunct Associate Professor
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Professor
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Driban, Jeffrey
first name: Jeffrey
last name: Driban
Featured Videos: https://profiles.umassmed.edu/profile/40402890
full name: Jeffrey B Driban PhD, AT Ret, CSCS
has faculty rank: Professor
latitude: 42.27834540000000
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Professor
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Professor
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Associate Professor
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Professor
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Associate Professor
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HR job title: Associate Professor
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Walkey, Allan
first name: Allan
last name: Walkey
full name: Allan Jay Walkey MD, MSc
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Medicine at UMass Chan - Lahey
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https://profiles.umassmed.edu/profile/40402890
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Radiology at UMass Chan - Lahey
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Professor
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Chair and Professor
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Professor
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Health System Science
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Infectious Diseases
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Neurointerventional Radiology
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Pulmonary Medicine
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Professor Emeritus
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Professor
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Professor
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Professor
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Professor
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Professor
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Professor
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Professor
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Professor
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Associate Professor
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Professor
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HR job title: Professor
position in organization: UMass Chan Medical School

Stroke and Vascular Neurology
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Chair and Professor
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position in division: Cardiovascular Medicine
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position in organization: UMass Chan Medical School

Tan Chingfen Graduate School of Nursing
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McAlindon, Timothy
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Martinez, Fernando
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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Microbiology
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Professor
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Professor
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Krings, Timo
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Goldsweig, Andrew
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person in primary position: Associate Professor
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Associate Professor
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