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Szabo, Gyongyi
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Person ID: 53
person in primary position: Adjunct Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Lambi and Sarah Adams Chair in Genetic Research
Rotation Projects: Rotations: Targeting the IFN-?-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking real-time autoreactive T cell migration and interactions within the skin: We are usin…
Rotation Projects: Rotations: Targeting the IFN-g-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking autoreactive T cell interactions within the skin: We are using fluorescently tagged C…
Summary: Interests: Vitiligo, autoimmunity, immunology, translational research
preferred title: Adjunct Professor

Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
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Person ID: 612
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
preferred title: Professor

Kornfeld, Hardy
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last name: Kornfeld
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latitude: 42.27985300000000
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Person ID: 739
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Cerny, Jan
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last name: Cerny
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Person ID: 777
person in primary position: Associate Professor
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type: Person
preferred title: Associate Professor

Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
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latitude: 42.27525000000000
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Person ID: 78
person in primary position: Professor Emeritus
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type: Person
preferred title: Professor Emeritus

Shaw, Leslie
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last name: Shaw
full name: Leslie M Shaw PhD
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longitude: -71.79190270000000
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Person ID: 900
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866558

McManus, David
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full name: David D McManus MD
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latitude: 42.27525000000000
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Person ID: 994
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
preferred title: Chair and Professor

Friedmann, Peter
first name: Peter
last name: Friedmann
full name: Peter D Friedmann MD, MPH, DFASAM, FACP
has faculty rank: Professor
latitude: 42.10873680000000
longitude: -72.59405680000000
Person ID: 4333
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

UMass Chan – Baystate Regional Campus
type: Organization

Hogan, Susan
first name: Susan
last name: Hogan
full name: Susan Lynn Hogan MD
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latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 4521
person in primary position: Assistant Professor
type: Agent
type: Person
preferred title: Assistant Professor

Engelman, Daniel
first name: Daniel
last name: Engelman
full name: Daniel Engelman MD
has faculty rank: Professor
latitude: 42.12076620000000
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Person ID: 4596
person in primary position: Professor
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type: Person
preferred title: Professor

Dermatology
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type: Organization

Singh, Sonal
first name: Sonal
last name: Singh
full name: Sonal Singh MD, MPH
has faculty rank: Associate Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 4649
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866602

Associate Professor
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position in division: Food Science
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HR job title: Associate Professor
position in organization: University of Massachusetts Amherst

https://profiles.umassmed.edu/profile/16236515
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position in department: ClinicalLab & NutritionalSci
position in division: School of Health And Environment
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position in organization: University of Massachusetts Lowell

Krieg, Arthur
first name: Arthur
last name: Krieg
full name: Arthur M Krieg MD
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latitude: 42.36278220000000
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Person ID: 4841
person in primary position: Professor
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type: Person
preferred title: Professor

Lindenauer, Peter
first name: Peter
last name: Lindenauer
full name: Peter K Lindenauer MD, MSc
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latitude: 42.12711190000000
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Person ID: 4845
person in primary position: Chair and Professor
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type: Person
preferred title: Chair and Professor

ADJUNCT PROFESSOR
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Gurwitz, Jerry
first name: Jerry
last name: Gurwitz
full name: Jerry Howard Gurwitz MD
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latitude: 42.27525000000000
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Person ID: 5308
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
preferred title: Professor

Braden, Gregory
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last name: Braden
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latitude: 42.12294230000000
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Person ID: 5386
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Usmani, Saad
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last name: Usmani
full name: Saad Usmani MD
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Person ID: 5394
person in primary position: Instructor
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type: Person
preferred title: Instructor

Ophthalmology and Visual Sciences
type: Department
type: Organization

Population and Quantitative Health Sciences
type: Department
type: Organization

Kelly, Edward
first name: Edward
last name: Kelly
full name: Edward Kelly MD
has faculty rank: Associate Professor
latitude: 42.12294230000000
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Person ID: 10246744
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Lin, Honghuang
first name: Honghuang
last name: Lin
full name: Honghuang Lin PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 10247010
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

https://profiles.umassmed.edu/profile/28866427
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label: http://www.umassmed.edu/fitzgeraldlab
link anchor text: Fitzgerald Lab Page

https://profiles.umassmed.edu/profile/28866493
type: URLLink
label: http://www.umassmed.edu/pii
link anchor text: Program in Innate Immunity

https://profiles.umassmed.edu/profile/28866556
type: URLLink
label: http://mmpc.org
link anchor text: National Mouse Metabolic Phenotyping Center

https://profiles.umassmed.edu/profile/28866558
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label: http://www.umassmed.edu/mccb/faculty-MCCB/faculty-MCCB/faculty-profile-pages/shaw-leslie/
link anchor text: Leslie Shaw Department Profile

https://profiles.umassmed.edu/profile/28866602
type: URLLink
label: https://scholar.google.com/citations
link anchor text: Google Scholar Profile

Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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type: Organization

Medicine at UMass Chan - Baystate
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type: Organization

Surgery at UMass Chan - Baystate
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type: Organization

Adjunct Professor
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position in department: Program in Molecular Medicine
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Program in Molecular Medicine
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sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Medicine
position in division: Gastroenterology
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor Emeritus
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position in department: Medicine
position in division: Cardiovascular Medicine
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type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine at UMass Chan - Baystate
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan – Baystate Regional Campus

Instructor
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position in department: Medicine at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Instructor
position in organization: UMass Chan – Baystate Regional Campus

Professor
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position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Surgery at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan – Baystate Regional Campus

Caricchio, Roberto
first name: Roberto
last name: Caricchio
full name: Roberto Caricchio MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 10247138
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Myles J. McDonough Chair in Rheumatology
preferred title: Professor

Associate Professor
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position in department: Medicine
position in division: Rheumatology
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Lee, Darren
first name: Darren
last name: Lee
full name: Darren James Lee PhD
has faculty rank: Associate Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 10247152
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/35298484

Gallucci, Stefania
first name: Stefania
last name: Gallucci
full name: Stefania Gallucci MD
has faculty rank: Professor
latitude: 42.27491030000000
longitude: -71.76424060000000
Person ID: 10247170
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Professor
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position in department: Surgery at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan – Baystate Regional Campus

Associate Professor
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position in department: Ophthalmology and Visual Sciences
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Medicine
position in division: Renal Medicine
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type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Wali, Ravinder
first name: Ravinder
last name: Wali
full name: Ravinder K Wali MD, MRCP
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latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 10247380
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

https://profiles.umassmed.edu/profile/35298484
type: URLLink
label: https://www.umassmed.edu/darrenleelab/
link anchor text: Darren Lee Lab Webpage

Professor
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position in department: Surgery
position in division: Vascular Surgery
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HR job title: Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Family Medicine and Community Health
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Family Medicine and Community Health
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Rheumatology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Renal Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Walkey, Allan
first name: Allan
last name: Walkey
full name: Allan Jay Walkey MD, MSc
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 10247602
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/104051488

Moffatt-Bruce, Susan
first name: Susan
last name: Moffatt-Bruce
full name: Susan D Moffatt-Bruce MD, PhD, FRCSC, MBOE, MBA,FACS
has faculty rank: Professor
latitude: 42.48526100000000
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Person ID: 10247633
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Medicine at UMass Chan - Lahey
type: Department
type: Organization

Surgery at UMass Chan - Lahey
type: Department
type: Organization

Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Radiology at UMass Chan - Lahey
type: Department
type: Organization

Chair and Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
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type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Rheumatology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Endocrinology & Diabetes
type: Division
type: Organization

Health System Science
type: Division
type: Organization

Infectious Diseases
type: Division
type: Organization

Innate Immunity
type: Division
type: Organization

Pulmonary Medicine
type: Division
type: Organization

Chandraker, Anil
first name: Anil
last name: Chandraker
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latitude: 42.27525000000000
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Person ID: 10247728
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Jack M. Wilson Chair in Biomedical Research
preferred title: Professor

Professor Emeritus
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position in division: Epidemiology
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type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Medicine
position in division: Infectious Diseases
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type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in division: Innate Immunity
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Pulmonary Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine
position in division: Hematology/Oncology
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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Geriatrics
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Epidemiology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Epidemiology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Medicine
position in division: Infectious Diseases
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type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Innate Immunity
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Molecular, Cell and Cancer Biology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Stroke and Vascular Neurology
type: Division
type: Organization

Chair and Professor
is primary position: true
position in department: Medicine
position in division: Cardiovascular Medicine
sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Ramsey, David
first name: David
last name: Ramsey
full name: David J Ramsey MD, PhD, MPH
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latitude: 42.53749440000000
longitude: -70.94678520000000
Person ID: 10247796
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Associate Professor
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position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Tan Chingfen Graduate School of Nursing
type: Department
type: Organization

Professor
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position in department: Tan Chingfen Graduate School of Nursing
position in division: https://profiles.umassmed.edu/profile/15590085
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HR job title: Professor
position in organization: UMass Chan Medical School

McAlindon, Timothy
first name: Timothy
last name: McAlindon
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latitude: 42.27222560000000
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Person ID: 10247852
person in primary position: Professor
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preferred title: Professor

Dani, Sourbha
first name: Sourbha
last name: Dani
full name: Sourbha S Dani MD, MSc, GDCE, CCDS, FACC,FACP
has faculty rank: Associate Professor
latitude: 42.48526100000000
longitude: -71.20221980000000
Person ID: 10247888
person in primary position: Associate Professor
type: Agent
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preferred title: Associate Professor

Associate Professor
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position in department: Medicine at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Martinez, Fernando
first name: Fernando
last name: Martinez
full name: Fernando J Martinez MD, MS
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latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 10247895
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
preferred title: Professor

Professor
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position in department: Medicine
position in division: Pulmonary Medicine
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Chait, Yossi
first name: Yossi
last name: Chait
full name: Yossi Chait PhD
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person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Adjunct Professor
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position in department: Medicine
position in division: Renal Medicine
sort order: 1
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Krings, Timo
first name: Timo
last name: Krings
full name: Timo Krings MD, PhD, FRCP
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latitude: 42.48526100000000
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Person ID: 10247952
person in primary position: Professor
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type: Person
preferred title: Professor

Goldsweig, Andrew
first name: Andrew
last name: Goldsweig
full name: Andrew Goldsweig MD, MS
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latitude: 42.12294230000000
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Person ID: 10248018
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Associate Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
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HR job title: Associate Professor
position in organization: UMass Chan – Baystate Regional Campus

Maron, Martin
first name: Martin
last name: Maron
full name: Martin S Maron MD, MSPH
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latitude: 42.48526100000000
longitude: -71.20221980000000
Person ID: 10248121
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Maron, Barry
first name: Barry
last name: Maron
full name: Barry J Maron MD
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latitude: 42.48526100000000
longitude: -71.20221980000000
Person ID: 10248130
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Adjunct Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Program in Molecular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Rheumatology
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Chair and Professor
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