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Post Docs: We are looking for postdoc candidates with experience in cancer biology, mouse models and genome-engineering. Please email CV and 3 letters of recommendation to Wen.Xue@umassmed.edu.
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preferred title: Professor
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Kucukural, Alper
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Mello, Craig
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Endowed Chair Honorary Title: Blais University Chair in Molecular Medicine
Rotation Projects: Potential Rotation Projects: There are numerous potential rotation project available in the Mello lab: Projects include: Investigation of RNAi and related mechanisms, including Piwi Argonaute pathways and their affects on fertility and epigenetic inheritance; Investigation of germline determination and cell-fate specification during embryogenesis; the exploration of CRISPR mediated genome editing tools for C. elegans and other organisms; and finally the use of CRISPR to generate C. elegans models for human genetic disease.
preferred title: Distinguished Professor
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Rando, Oliver
first name: Oliver
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Endowed Chair Honorary Title: Endowed Chair in Biochemistry and Molecular Biotechnology II
Post Docs: For more information about the Postdoctoral position in Dr. Rando’s lab please use the link provided. Post doc position
Rotation Projects: Rotation projects are available to study chromatin structure and function. Project 1. Measure histone dynamics in yeast. Histone dynamics play major roles in chromatin metabolism and in the inheritance of chromatin states. To measure histone replacement rates in yeast, we have created yeast strains carrying inducible epitope-tagged histones H3 and H2A. Using microarrays, we will measure histone replacement rates in a variety of mutant yeast to ascertain the role of various chromatin remodeling factors in histone exchange reactions. Project 2. Characterize mechanisms for epigenetic inheritance in yeast. We have identified a variety of genes whose expression state in yeast is epigenetically heritable. We will screen the yeast genome for genes that affect the inheritance of these expression patterns. Project 3. Measure histone dynamics in embryonic stem cells. Embryonic stem cells are pluripotent cells that can give rise to every type of cell in the adult animal. The role of chromatin structure in maintaining this pluripotent state is poorly understood, but it appears that stem cell chromatin is exceptionally labile relative to that in differentiated cells. We will create stem cell lines with inducible tagged histones to measure histone replacement rates across the mouse genome.
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Zhu, Lihua
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Weng, Zhiping
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Post Docs: The project aims to develop computational algorithms and software programs for analyzing high-throughput sequence data such as ChIP-Seq RNA-Seq small RNA sequencing data. PhD required. A strong background in computational biology especially experience with analyzing high-throughput sequencing data is highly desirable. Excellent communication and writing skills and the ability to work with experimental and computational collaborators are essential. To apply please forward CV cover letter and three references to: Zhiping.Weng@umassmed.edu
Rotation Projects: Please contact Dr. Weng for information on rotations that are available in her lab.
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Kennedy, David
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Cutrona, Sarah
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Trivedi, Chinmay
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Post Docs: A Postdoctoral position is available in the Trivedi lab to study roles of novel chromatin and epigenetic modifications during cardiovascular development and disease (for details of our research: The Journal of Clinical Investigation, Science Advances, Journal of Experimental Medicine, ATVB, Human Molecular Genetics, Journal of Biological Chemistry). Candidates with a PhD in Biochemistry, Molecular Biology, Stem Cell Biology or Developmental Biology are encouraged to apply. Previous experience with mice handling and biochemistry-molecular biology-epigenetics related techniques such as ChIP-seq is strongly desired. Candidate will be required to learn new techniques in the area of translational biology to advance their project.
Rotation Projects: Rotation Projects: Please contact Chinmay Trivedi (chinmay.trivedi@umassmed.edu) for information regarding potential rotation projects (for details - research performed by graduate students in the trivedi lab: The Journal of Clinical Investigation, Science Advances, Journal of Experimental Medicine, JCI Insight, ATVB, Human Molecular Genetics, Journal of Biological Chemistry). We will develop a specific rotation project based on student's interest, background, and goals of the rotation. Students can rotate either for a half- or full-semester.
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Irwin, Richard Stephen
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McIlvane, William
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Rotation Projects: Additional information about lab rotations within the CPHR program can be found athttp://www.umassmed.edu/cphr/program/rotations.aspx
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Rosen, Amy
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Hoaglin, David
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Zierath, Juleen
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Garber, Manuel
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Person ID: 3318
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Rotation Projects: If you are interesting in applying computational methods to biological problems please contact me. Potential projects in my lab are Modeling of transcription factor gene expression control in innate immune cells Evolutionary analysis of gene transcription factor networks in mammals Epigenetics inheritance in mice: From male sperm to phenotypic effect in grandchildren Application of genome and exome sequencing to newborn screening Development of computational methods for analysis of RNA-protein interactions
preferred title: Professor

King, Oliver
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Summary: Dr. King is a computational biologist with research interests in algorithm development and the analysis of high-throughput datasets. His current research projects involve facioscapulohumeral muscular dystrophy (FSHD), amyotrophic lateral sclerosis (ALS), and other disorders.
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Epstein, Mara
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King, Michael
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Hayman, Laura
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Jerry, D Joseph
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Lian, Jane
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Ganz, Aura
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Siegelmann, Hava
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Freedson, Patty
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preferred title: Chair and Professor

Henson, Michael
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Pederson, Thoru
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Endowed Chair Honorary Title: Vitold Arnett Professor of Cell Biology
Rotation Projects: Background for Student Rotation Projects <p >See Politz, Hogan and Pederson (2009) and Politz et al. (2005) in the above list. The novel microRNA work may be the most suitable for student rotations. Potential Rotation Projects <p >Are the nucleolar microRNAs pri-, pre- or mature? <p >Are they complexed with other nucleolar RNAs? <p >Do the cell cycle related proteins in the nucleolus exist as heterotypic complexes? <p >Does the nucleolus of human embryonic stem cells also share these features (which we have so far looked for, and found, only in transformed human cell lines)? <p >Can vanadium tagging be used to detect specific proteins by electron microscopy, perhaps exceeding the limitations of immuno-EM?
preferred title: Professor Emeritus

Xiao, Hang
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Donahue, J.
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Endowed Chair Honorary Title: David J. and Barbara D. Milliken Professor in Preventive Cardiology
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Rogaev, Evgeny
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rogaev for additional details.
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Lawrence, Jeanne
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full name: Jeanne B Lawrence PhD
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Endowed Chair Honorary Title: Leo P. and Theresa M. LaChance Chair in Medical Research
Lab URL: https://www.umassmed.edu/lawrencelab
Summary: Lawrence lab research bridges fundamental questions of developmental epigenetics with translational research into the common problem of chromosome abnormalities, particularly Down syndrome.
preferred title: Professor

Zamore, Phillip
first name: Phillip
last name: Zamore
full name: Phillip D Zamore PhD
has faculty rank: Chair And Professor
latitude: 42.27587600000000
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Endowed Chair Honorary Title: Gretchen Stone Cook Chair in Biomedical Sciences
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Zamore for additional details
Rotation Projects: Potential Rotation Projects Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866555
webpage: https://profiles.umassmed.edu/profile/28866537
webpage: https://profiles.umassmed.edu/profile/28866541

Paydarfar, David
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Karellas, Andrew
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Vedantham, Srinivasan
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Dekker, Job
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Endowed Chair Honorary Title: Joseph J. Byrne Chair in Biomedical Research
Rotation Projects: ? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866525
webpage: https://profiles.umassmed.edu/profile/28866572

Sassetti, Christopher
first name: Christopher
last name: Sassetti
full name: Christopher M Sassetti PhD
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Person ID: 878
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Endowed Chair Honorary Title: Elisabeth Chair II
Lab URL: https://www.umassmed.edu/sassettilab/
Rotation Projects: Rotation Projects <p >We have identified a number of bacterial pathways that are required for bacterial viability or virulence. We are particularly interested in: Phosphosignaling systems that regulate cell wall synthesis Metabolic regulatory mechanisms that trigger the “dormancy” response observed during infection. <p >A variety of genetic, biochemical, and informatic methods will be used to define the functions of these genes and the role played by each during infection. <p >
Summary: Focus: Pathogenesis of tuberculosis
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McManus, David
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last name: McManus
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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UMass Chan – Baystate Regional Campus
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Dermatology
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Singh, Sonal
first name: Sonal
last name: Singh
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ADJUNCT ASSOCIATE PROFESSOR
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ADJUNCT PROFESSOR
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Pai, Athma
first name: Athma
last name: Pai
Twitter: https://profiles.umassmed.edu/profile/28867149
full name: Athma A Pai PhD
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latitude: 42.27525000000000
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Person ID: 5128
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Pai for additional details.
preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866467

Seddon, Johanna
first name: Johanna
last name: Seddon
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Gurwitz, Jerry
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Person ID: 5308
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Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
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Ughi, Giovanni
first name: Giovanni
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latitude: 42.27511780000000
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Person ID: 5349
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Post Docs: Harvard Medical School and Massachusetts General Hospital, Boston Postdoctoral Training Biomedical Optics and Translational Medicine
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Grigorieff, Nikolaus
first name: Nikolaus
last name: Grigorieff
full name: Nikolaus Grigorieff PhD
has faculty rank: Professor
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Person ID: 5371
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Robertson, David
first name: David
last name: Robertson
full name: David Robertson MD, MPH
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latitude: 42.13414590000000
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Person ID: 5410
person in primary position: Assistant Professor
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Ophthalmology and Visual Sciences
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Population and Quantitative Health Sciences
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Zhou, Chan
first name: Chan
last name: Zhou
full name: Chan Zhou PhD
has faculty rank: Assistant Professor
latitude: 42.27834540000000
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Person ID: 5517
person in primary position: Assistant Professor
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preferred title: Assistant Professor
webpage: https://profiles.umassmed.edu/profile/28866599

Lodato, Michael
first name: Michael
last name: Lodato
Twitter: https://profiles.umassmed.edu/profile/28867077
full name: Michael Anthony Lodato PhD
has faculty rank: Associate Professor
latitude: 42.27673450000000
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Person ID: 5630
person in primary position: Associate Professor
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Post Docs: Wet-lab and Bioinformatic postdoctoral fellow positions are available for candidates with recent Ph.D. or M.D./Ph.D. degrees in Molecular Biology, Neuroscience, Genetics, Genomics, Cell Biology, or related fields. They should be highly motivated, have a strong desire to learn, and excellent communication skills. Applicants should send their CV, summary of previous research and the name of three references to Dr. Michael Lodato.
Rotation Projects: Rotations will revolve around studying somatic mutations in the normal brain, in the diseased brain, and outside of the brain using single-cell genomics. Please contact Dr. Lodato for details.
preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866604

Bankier, Alexander
first name: Alexander
last name: Bankier
full name: Alexander A. Bankier MD, PhD
has faculty rank: Professor
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Person ID: 5766
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Shipley, Rebecca
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latitude: 42.27664990000000
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Person ID: 10246681
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preferred title: Assistant Professor

Biochemistry and Molecular Biotechnology
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Lin, Honghuang
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last name: Lin
full name: Honghuang Lin PhD
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Emergency Medicine at UMass Chan - Baystate
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Pediatrics at UMass Chan - Baystate
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Adjunct Associate Professor
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Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
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Assistant Professor
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Assistant Professor
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Professor
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Professor
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Saranathan, Manojkumar
first name: Manojkumar
last name: Saranathan
full name: Manojkumar Saranathan PhD
has faculty rank: Professor
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Moore, Jill
first name: Jill
last name: Moore
Twitter: https://profiles.umassmed.edu/profile/30306209
full name: Jill Moore PhD
has faculty rank: Assistant Professor
latitude: 42.27525450000000
longitude: -71.76235130000000
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Person ID: 10247091
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Lab URL: https://www.moore-lab.org/
Post Docs: The newly established Moore lab is looking for highly motivated post-doctoral fellows to be founding members of our team. We study gene regulation and its role in human disease by interpreting large scale multi-omic datasets using machine learning approaches. Ideal candidates will have extensive experience in multi-omic data processing and analysis (RNA-seq, ATAC-seq, ChIP-seq, etc.) and are interested in learning about the fundamental mechanisms governing gene regulation (regulating transcription, splicing, translation, etc.). Candidates from related fields, such as computer science or biomedical engineering, with machine learning experience are also highly encouraged to apply. To Apply: Interested candidates should email a cover letter, CV, and 3 references to: Jill Moore at Jill.Moore@umassmed.edu
Rotation Projects: Interested in rotating in the lab? Please contact Dr. Moore for more information.
preferred title: Assistant Professor
webpage: https://profiles.umassmed.edu/profile/30306461

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Abdennur, Nezar
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Goebel, Mathew
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https://profiles.umassmed.edu/profile/37079875
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Genomics and Computational Biology
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Radiology at UMass Chan - Lahey
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Wald, Christoph
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Professor
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Cardio Thoracic Radiology
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Health System Science
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Orthopedics Research
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Pulmonary Medicine
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Wellstone Program
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Professor
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Adjunct Professor
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Stroke and Vascular Neurology
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Assistant Professor
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Assistant Professor
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Professor
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Chair and Professor
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https://profiles.umassmed.edu/profile/44403713
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McAlindon, Timothy
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Martinez, Fernando
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Chair and Professor
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Assistant Professor
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