Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
Healthcare Delivery and Population Sciences at UMass Chan - Baystate
Joseph D. Early Chair in Biomedical Research
Di Guglielmo MD, Perdue L, Adeyemi A, van Golen KL, Corao DU
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
Di Guglielmo MD, Perdue L, Adeyemi A, van Golen KL, Corao DU. Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity. Pediatr Dev Pathol. 2018 May-Jun; 21(3):285-295.
Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity.
Harrison M, Jones P, Sharif I, Di Guglielmo MD
Journal of developmental and behavioral pediatrics : JDBP
Harrison M, Jones P, Sharif I, Di Guglielmo MD. General Pediatrician-Staffed Behavioral/Developmental Access Clinic Decreases Time to Evaluation of Early Childhood Developmental Disorders. J Dev Behav Pediatr. 2017 Jul/Aug; 38(6):353-357.
General Pediatrician-Staffed Behavioral/Developmental Access Clinic Decreases Time to Evaluation of Early Childhood Developmental Disorders.
Di Guglielmo MD, Holbrook J, Stabley D, Robbins KM, Boyce B, Hardy H, Adeyemi A
Applied immunohistochemistry & molecular morphology : AIMM
Di Guglielmo MD, Holbrook J, Stabley D, Robbins KM, Boyce B, Hardy H, Adeyemi A. The Intestinal Tract Brush Border in Young Children Uniformly Expresses Guanylate Cyclase C. Appl Immunohistochem Mol Morphol. 2023 03 01; 31(3):154-162.
The Intestinal Tract Brush Border in Young Children Uniformly Expresses Guanylate Cyclase C.
Pitari GM, Di Guglielmo MD, Park J, Schulz S, Waldman SA
Proceedings of the National Academy of Sciences of the United States of America
Pitari GM, Di Guglielmo MD, Park J, Schulz S, Waldman SA. Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells. Proc Natl Acad Sci U S A. 2001 Jul 03; 98(14):7846-51.
Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
Di Guglielmo MD, Tonb D, He Z, Adeyemi A, van Golen KL
Journal of pediatric gastroenterology and nutrition
Di Guglielmo MD, Tonb D, He Z, Adeyemi A, van Golen KL. Pilot Study Measuring the Novel Satiety Hormone, Pro-Uroguanylin, in Adolescents With and Without Obesity. J Pediatr Gastroenterol Nutr. 2018 03; 66(3):489-495.
Pilot Study Measuring the Novel Satiety Hormone, Pro-Uroguanylin, in Adolescents With and Without Obesity.
Di Guglielmo MD, Plesnick J, Greenspan JS, Sharif I
Di Guglielmo MD, Plesnick J, Greenspan JS, Sharif I. A new model to decrease time-to-appointment wait for gastroenterology evaluation. Pediatrics. 2013 May; 131(5):e1632-8.
A new model to decrease time-to-appointment wait for gastroenterology evaluation.
Babu Balagopal P, Kohli R, Uppal V, Averill L, Shah C, McGoogan K, Di Guglielmo M, Goran M, Hossain MJ
Babu Balagopal P, Kohli R, Uppal V, Averill L, Shah C, McGoogan K, Di Guglielmo M, Goran M, Hossain MJ. Effect of N-acetyl cysteine in children with metabolic dysfunction-associated steatotic liver disease-A pilot study. J Pediatr Gastroenterol Nutr. 2024 Sep; 79(3):652-660.
Effect of N-acetyl cysteine in children with metabolic dysfunction-associated steatotic liver disease-A pilot study.
Di Guglielmo MD, Perito ER. To Juice or Not to Juice: Fatty Liver Repercussions for Infants. Hepatology. 2021 02; 73(2):483-485.
To Juice or Not to Juice: Fatty Liver Repercussions for Infants.
Di Guglielmo MD, Park J, Schulz S, Waldman SA
Di Guglielmo MD, Park J, Schulz S, Waldman SA. Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C. FEBS Lett. 2001 Oct 26; 507(2):128-32.
Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Di Guglielmo MD, Hertzog JH. Aortic pseudoaneurysm in a child with a left mainstem bronchial stent. Pediatr Crit Care Med. 2008 Jul; 9(4):e31-4.
Aortic pseudoaneurysm in a child with a left mainstem bronchial stent.
Di Guglielmo MD, Franke KR, Robbins A, Crowgey EL
Frontiers in cellular and infection microbiology
Di Guglielmo MD, Franke KR, Robbins A, Crowgey EL. Impact of Early Feeding: Metagenomics Analysis of the Infant Gut Microbiome. Front Cell Infect Microbiol. 2022; 12:816601.
Impact of Early Feeding: Metagenomics Analysis of the Infant Gut Microbiome.
Rohde JF, Goyal NK, Slovin SR, Hossain J, Pachter LM, Di Guglielmo MD
Rohde JF, Goyal NK, Slovin SR, Hossain J, Pachter LM, Di Guglielmo MD. Association of Positional Plagiocephaly and Developmental Delay Within a Primary Care Network. J Dev Behav Pediatr. 2021 Feb-Mar 01; 42(2):128-134.
Association of Positional Plagiocephaly and Developmental Delay Within a Primary Care Network.
Di Guglielmo M, Savage J, Gould S, Murphy S
Di Guglielmo M, Savage J, Gould S, Murphy S. Female Adolescent Presenting With Abdominal Pain: Accidental Wire Bristle Ingestion Leading to Colonic Perforation. Pediatr Emerg Care. 2017 May; 33(5):356-358.
Female Adolescent Presenting With Abdominal Pain: Accidental Wire Bristle Ingestion Leading to Colonic Perforation.
Hoover K, Di Guglielmo MD, Perry B. Disparities in Vision Screening in Primary Care for Young Children With Autism Spectrum Disorder. Pediatrics. 2023 04 01; 151(4).
Disparities in Vision Screening in Primary Care for Young Children With Autism Spectrum Disorder.
Rohde JF, Canter K, Houff M, Bodt B, Pachter LM, Di Guglielmo MD, Goyal N
Journal of child health care : for professionals working with children in the hospital and community
Rohde JF, Canter K, Houff M, Bodt B, Pachter LM, Di Guglielmo MD, Goyal N. Pediatric primary care clinicians' views on needs and challenges in caring for infants with intrauterine opioid exposure and their families. J Child Health Care. 2024 Dec; 28(4):849-864.
Pediatric primary care clinicians' views on needs and challenges in caring for infants with intrauterine opioid exposure and their families.
Di Guglielmo MD, Greenspan JS, Abatemarco DJ
Primary health care research & development
Di Guglielmo MD, Greenspan JS, Abatemarco DJ. Pediatrician preferences, local resources, and economic factors influence referral to a subspecialty access clinic. Prim Health Care Res Dev. 2016 11; 17(6):628-635.
Pediatrician preferences, local resources, and economic factors influence referral to a subspecialty access clinic.
Ricciuto A, Liu K, El-Matary W, Amin M, Amir AZ, Aumar M, Auth M, Di Guglielmo MD, Druve Tavares Fagundes E, Rodrigues Ferreira A, Furuya KN, Gupta N, Guthery S, Horslen SP, Jensen K, Kamath BM, Kerkar N, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Mack C, Martinez M, Montano-Loza A, Ovchinsky N, Papadopoulou A, Perito ER, Sathya P, Schwarz KB, Shah U, Shteyer E, Soufi N, Stevens JP, Taylor A, Tessier ME, Valentino P, Woynarowski M, Deneau M
Ricciuto A, Liu K, El-Matary W, Amin M, Amir AZ, Aumar M, Auth M, Di Guglielmo MD, Druve Tavares Fagundes E, Rodrigues Ferreira A, Furuya KN, Gupta N, Guthery S, Horslen SP, Jensen K, Kamath BM, Kerkar N, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Mack C, Martinez M, Montano-Loza A, Ovchinsky N, Papadopoulou A, Perito ER, Sathya P, Schwarz KB, Shah U, Shteyer E, Soufi N, Stevens JP, Taylor A, Tessier ME, Valentino P, Woynarowski M, Deneau M. Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD): A matched analysis from the Paediatric PSC Consortium. Aliment Pharmacol Ther. 2024 05; 59(10):1236-1247.
Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD): A matched analysis from the Paediatric PSC Consortium.
Di Guglielmo MD, Franke K, Cox C, Crowgey EL
Di Guglielmo MD, Franke K, Cox C, Crowgey EL. Whole genome metagenomic analysis of the gut microbiome of differently fed infants identifies differences in microbial composition and functional genes, including an absent CRISPR/Cas9 gene in the formula-fed cohort. Hum Microb J. 2019 Jun; 12.
Whole genome metagenomic analysis of the gut microbiome of differently fed infants identifies differences in microbial composition and functional genes, including an absent CRISPR/Cas9 gene in the formula-fed cohort.
Mansoor S, Maheshwari A, Di Guglielmo M, Furuya K, Wang M, Crowgey E, Molle-Rios Z, He Z
Pediatric gastroenterology, hepatology & nutrition
Mansoor S, Maheshwari A, Di Guglielmo M, Furuya K, Wang M, Crowgey E, Molle-Rios Z, He Z. The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity. Pediatr Gastroenterol Hepatol Nutr. 2021 Sep; 24(5):455-469.
The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity.
Di Guglielmo MD. Teaching Matters in Formula Preparation-A Measure of Equity and Nutritional Safety. JAMA Netw Open. 2024 Dec 02; 7(12):e2447366.
Teaching Matters in Formula Preparation-A Measure of Equity and Nutritional Safety.