School of Public Health and Health Sciences
Health Informatics And Implementation Science
Biostatistics And Health Services Research
Elisabeth Chair for the Dean of Medicine
Cutler Chair in Vascular and Endovascular Surgery
Donna M. and Robert J. Manning Chair in Obstetrics and Gynecology
The project aims to develop computational algorithms and software programs for analyzing high-throughput sequence data such as ChIP-Seq RNA-Seq small RNA sequencing data. PhD required. A strong background in computational biology especially experience with analyzing high-throughput sequencing data is highly desirable. Excellent communication and writing skills and the ability to work with experimental and computational collaborators are essential. To apply please forward CV cover letter and three references to: Zhiping.Weng@umassmed.edu
Please contact Dr. Weng for information on rotations that are available in her lab.
Robert M. and Shirley S. Siff Chair in Autism
Melvin S. and Sandra L. Cutler Chair in Biomedical Research
Potential Rotation Projects Proteostasis regulators, HSF1, HSP70 and HSP90 in liver disease: Determine the expression and function in different cell types of the liver during acute and chronic liver injury using in vivo and in vitro models. Subsequently, we will test the relevance of the expression of these proteins in activation of intracellular signaling molecules involved in induction of fatty liver, inflammation and fibrosis. Role of chemokines in liver disease: CC-chemokines particularly CCL2/MCP-1, is significantly increased in serum as well as in the liver parenchyma in patients with alcoholic hepatitis. We test the role of MCP-1 in induction of fatty acid synthesis or metabolism and inflammation in the alcoholic liver. Our studies will also investigate the role of MCP-1 directed migration of immune cells in the liver contributing to injury.
Additional information about lab rotations within the CPHR program can be found athttp://www.umassmed.edu/cphr/program/rotations.aspx
Dr. Strambio-De-Castillia (ORCID: https://orcid.org/0000-0002-1069-1816) is an internationally recognized cell biologist and imaging scientist who specializes in developing easy-to-use and openly accessible strategies for image data management and sharing to promote scientific discovery in health and disease.
Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
Background for Student Rotation Projects <p >See Politz, Hogan and Pederson (2009) and Politz et al. (2005) in the above list. The novel microRNA work may be the most suitable for student rotations. Potential Rotation Projects <p >Are the nucleolar microRNAs pri-, pre- or mature? <p >Are they complexed with other nucleolar RNAs? <p >Do the cell cycle related proteins in the nucleolus exist as heterotypic complexes? <p >Does the nucleolus of human embryonic stem cells also share these features (which we have so far looked for, and found, only in transformed human cell lines)? <p >Can vanadium tagging be used to detect specific proteins by electron microscopy, perhaps exceeding the limitations of immuno-EM?
Imoigele P. Aisiku, MD’97 Chair in Health Equity and Diversity
Barbara Helen Smith Chair in Preventive & Behavioral Medicine
Richard M. Haidack Professor in Medicine
Dr. John Meyers Professor in Primary Care Medicine
Population and Quantitative Health Sciences
Biochemistry and Molecular Biotechnology
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UMass Worcester Prevention Research Center
Center for Biomedical Career Development
Prevention Research Center at UMass Chan
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Healthcare Delivery and Population Sciences at UMass Chan - Baystate
Susan D Moffatt-Bruce MD, PhD, FRCSC, MBOE, MBA,FACS
Joseph D. Early Chair in Biomedical Research
Advisory links alcohol consumption to cancers: Here's how Worcester feels about the report
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FocalPlane features... data managent webinar OME 2025 | Session 1 - Pre-publication BioImage DMS FoundingGIDE: BioImage DMS for Everyone Presentation at the BINA 2024 Community Congress
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