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Chemistry Techniques, Synthetic
Concept
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Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.
Academic Article
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Schiffer, Celia
Person
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Han, Gang
Person
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Ali, Akbar
Person
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Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance.
Academic Article
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Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential.
Academic Article
Why?
Gold nanoparticles stabilized with MPEG-grafted poly(l-lysine): in vitro and in vivo evaluation of a potential theranostic agent.
Academic Article
Why?
Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents.
Academic Article
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New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors.
Academic Article
Why?
Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.
Academic Article
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Osborne, Barbara
Person
Why?
Pezzuto, John
Person
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Kaufman, Michael
Person
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