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Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes.
Academic Article
Why?
TFEB-driven lysosomal biogenesis is pivotal for PGC1?a??-dependent renal stress resistance.
Academic Article
Why?
TFEB-driven lysosomal biogenesis is pivotal for PGC1a-dependent renal stress resistance.
Academic Article
Why?
TFEB-Mediated Pro-inflammatory Response in Murine Macrophages Induced by Acute Alpha7 Nicotinic Receptor Activation.
Academic Article
Why?
Nervous system control of intestinal host defense mediated by TFEB
Grant
Why?
Irazoqui, Javier
Person
Why?
A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS.
Academic Article
Why?
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense.
Academic Article
Why?
Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
Academic Article
Why?
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
Academic Article
Why?
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.
Academic Article
Why?
Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.
Academic Article
Why?
HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans.
Academic Article
Why?
C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB.
Academic Article
Why?
NHR-49/PPAR-a and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase.
Academic Article
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