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Rapamycin-Insensitive Companion of mTOR ProteinConcept Why?
TOR Serine-Threonine KinasesConcept Why?
Guertin, DavidPerson Why?
A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.Academic Article Why?
Activation of protein kinase C-? in pancreatic ?-cells in vivo improves glucose tolerance and induces ?-cell expansion via mTOR activation.Academic Article Why?
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.Academic Article Why?
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.Academic Article Why?
mTOR Blockade by Rapamycin in Spondyloarthritis: Impact on Inflammation and New Bone Formation in vitro and in vivo.Academic Article Why?
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.Academic Article Why?
p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.Academic Article Why?
Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs.Academic Article Why?
Sestrin2 is a leucine sensor for the mTORC1 pathway.Academic Article Why?
Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.Academic Article Why?
Shen, KuangPerson Why?
Assessing the efficacy of targeting the phosphatidylinositol 3-kinase/AKT/mTOR signaling pathway in endometrial cancer.Academic Article Why?
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