| Item Type | Name |
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Academic Article
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Protection against lethal toxic shock by targeted disruption of the CD28 gene.
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Academic Article
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Inflammatory cytokines IFN-gamma plus TNF-alpha induce regulated expression of CD80 (B7-1) but not CD86 (B7-2) on murine fibroblasts.
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Academic Article
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Phorbol esters induce differentiation of human CD34+ hemopoietic progenitors to dendritic cells: evidence for protein kinase C-mediated signaling.
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Academic Article
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CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection.
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Academic Article
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Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model.
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Academic Article
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Susceptibility or resistance to Leishmania infection is dictated by the macrophages evolved under the influence of IL-3 or GM-CSF.
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Academic Article
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Toxic shock syndrome toxin-1-induced death is prevented by CTLA4Ig.
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Academic Article
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Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity.
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Academic Article
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Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent.
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Academic Article
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Effects of dose and duration of anti-CD154 antibody therapy in preventing renal allograft rejection in a nonhuman primate model.
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Academic Article
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Transplantation tolerance.
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Academic Article
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CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates.
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Academic Article
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Nucleic acid vaccine-induced immune responses require CD28 costimulation and are regulated by CTLA4.
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Academic Article
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Preclinical evaluation of tolerance induction protocols and islet transplantation in non-human primates.
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Academic Article
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Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.
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Academic Article
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Porcine CD80: cloning, characterization, and evidence for its role in direct human T-cell activation.
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Academic Article
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Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.
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Academic Article
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Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).
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Academic Article
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Sirolimus-induced interstitial pneumonitis in an islet transplant recipient.
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Academic Article
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Gene-altered islets for transplant: giant leap or small step?
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Academic Article
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Inducing unresponsiveness by the use of anti-CD3 immunotoxin, CTLA4-Ig, and anti-CD40 ligand.
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Academic Article
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Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates.
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Academic Article
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Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.
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Academic Article
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The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge.
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Academic Article
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Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus.
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Academic Article
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The future of organ and tissue transplantation: can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection?
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Academic Article
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Immune intervention with anti-CD3 in diabetes.
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Academic Article
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CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis.
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Academic Article
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T cell-directed therapies: lessons learned and future prospects.
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Academic Article
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The role of CD154 in organ transplant rejection and acceptance.
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Academic Article
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Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft.
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Academic Article
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Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes.
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Academic Article
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Counterpoint: clinical islet transplantation: not ready for prime time.
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Academic Article
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Current advances and travails in islet transplantation.
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Academic Article
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Immunological concerns with bioengineering approaches.
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Academic Article
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Islet cell allotransplantation as a model system for a bioengineering approach to reparative medicine: immunological concerns.
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Academic Article
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Immune response to engineered tissues and cells: breakout session summary.
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Academic Article
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Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model.
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Academic Article
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Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates.
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Academic Article
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Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression.
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Academic Article
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Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation.
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Academic Article
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Islet transplantation: where do we stand now?
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Academic Article
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Resistin is expressed in pancreatic islets.
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Academic Article
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Effects of combined treatment with CD25- and CD154-specific monoclonal antibodies in non-human primate allotransplantation.
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Academic Article
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State of the art: islet transplantation for the cure of type 1 diabetes mellitus.
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Academic Article
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Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.
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Academic Article
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A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice.
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Academic Article
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Potential roles of the B7 and CD28 receptor families in autoimmunity and immune evasion.
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Academic Article
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Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.
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Academic Article
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Disruption of CD40/CD40-ligand interactions in a retinal autoimmunity model results in protection without tolerance.
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Academic Article
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Islet neogenesis associated protein transgenic mice are resistant to hyperglycemia induced by streptozotocin.
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Academic Article
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Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes.
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Academic Article
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Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy.
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Academic Article
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Extrapancreatic autoantibody profiles in type I diabetes.
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Academic Article
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Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.
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Concept
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Immunologic Factors
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Concept
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Immunotherapy
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Concept
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Immunity, Cellular
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Concept
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Graft Enhancement, Immunologic
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Concept
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Immune System Diseases
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Concept
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Transplantation Immunology
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Concept
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Models, Immunological
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Concept
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Immunoglobulins, Intravenous
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Concept
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Immunophenotyping
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Concept
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Immunosuppressive Agents
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Concept
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Organoids
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Concept
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Immunoprecipitation
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Concept
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Dose-Response Relationship, Immunologic
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Concept
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Immunotoxins
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Concept
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Immunity, Innate
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Concept
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Immunoglobulin G
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Concept
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Cytotoxicity, Immunologic
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Concept
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Immunization, Passive
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Concept
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Immunoconjugates
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Concept
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Immune System
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Concept
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Immunization
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Concept
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Monitoring, Immunologic
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Concept
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Immunoglobulin Fc Fragments
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Concept
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Immunohistochemistry
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Concept
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Immune Tolerance
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Concept
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Immunologic Memory
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Academic Article
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Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2r?(null) mice treated with alogliptin.
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Academic Article
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IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse.
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Academic Article
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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.
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Academic Article
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Long-term immunosuppression after solitary islet transplantation is associated with preserved C-peptide secretion for more than a decade.
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Academic Article
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Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.
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Academic Article
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Modeling Type 1 Diabetes In?Vitro Using Human Pluripotent Stem Cells.
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Academic Article
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Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases.
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