Connection | Profiles RNS

Search Result Details

Back to Search Results

This page shows the details of why an item matched the keywords from your search.

Search Results

Latz, Eicke

One or more keywords matched the following items that are connected to Latz, Eicke

Item Type	Name
Academic Article	Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article	Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	The LPS receptor generates inflammatory signals from the cell surface.
Academic Article	Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article	Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells.
Academic Article	Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Academic Article	Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article	The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
Academic Article	The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article	Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.
Academic Article	Intracellular DNA recognition.
Academic Article	The sterile inflammatory response.
Academic Article	IFI16 is an innate immune sensor for intracellular DNA.
Academic Article	The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Academic Article	Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
Academic Article	Innate immune receptors for nucleic acids.
Academic Article	KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Academic Article	For gut's sake: NLRC4 inflammasomes distinguish friend from foe.
Academic Article	A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
Academic Article	CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article	IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?
Academic Article	Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan.
Academic Article	The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article	Receptor "cross talk" in innate immunity.
Academic Article	TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article	Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article	Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article	Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
Academic Article	HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Academic Article	Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article	Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Academic Article	Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
Academic Article	Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article	Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Academic Article	Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.
Academic Article	Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides.
Academic Article	Inflammasomes: too big to miss.
Academic Article	The inflammasomes: mechanisms of activation and function.
Academic Article	Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Academic Article	Rational design of immunostimulatory siRNAs.
Academic Article	Critical functions of priming and lysosomal damage for NLRP3 activation.
Academic Article	Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy.
Academic Article	Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article	The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article	Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.
Academic Article	The critical role of IL-1 receptor-associated kinase 4-mediated NF-?B activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis.
Academic Article	Getting closer to the dirty little secret.
Academic Article	NLRP3 inflammasomes link inflammation and metabolic disease.
Academic Article	Intracellular sensing of microbes and danger signals by the inflammasomes.
Academic Article	HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro.
Academic Article	Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Academic Article	Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article	Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article	Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Academic Article	Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Academic Article	Activation and regulation of the inflammasomes.
Academic Article	Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Concept	Immunotherapy
Concept	Enzyme-Linked Immunosorbent Assay
Concept	Immunity, Cellular
Concept	Immune System Diseases
Concept	Tumor Lysis Syndrome
Concept	Immunity
Concept	Chromatin Immunoprecipitation
Concept	Syndrome
Concept	Models, Immunological
Concept	Immunophenotyping
Concept	Immunosuppressive Agents
Concept	Myelodysplastic Syndromes
Concept	Immunoprecipitation
Concept	Dose-Response Relationship, Immunologic
Concept	Acquired Immunodeficiency Syndrome
Concept	Immunomodulation
Concept	Simian Acquired Immunodeficiency Syndrome
Concept	Immunity, Innate
Concept	Adjuvants, Immunologic
Concept	Cryopyrin-Associated Periodic Syndromes
Concept	Mucocutaneous Lymph Node Syndrome
Concept	Immunity, Humoral
Concept	Immunoglobulin G
Concept	Simian Immunodeficiency Virus
Concept	Adaptive Immunity
Concept	Immune System
Concept	Receptors, Immunologic
Concept	Immunization
Concept	Immunohistochemistry
Concept	Immune Tolerance
Concept	Immunoblotting
Concept	Immunologic Memory
Academic Article	HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages.
Academic Article	Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.
Academic Article	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article	High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article	Mechanisms of sterile inflammation.
Academic Article	Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.
Academic Article	Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Academic Article	Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Academic Article	NLRC3 puts the brakes on STING.
Academic Article	Innate immune activation in neurodegenerative disease.
Academic Article	The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article	The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
Academic Article	Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Academic Article	Editorial overview: Special section: effects of endogenous immune stimulants: from a defence system against infection to a homeostatic mechanism linking metabolism with inflammation.
Academic Article	Inflammasome activation in response to dead cells and their metabolites.
Academic Article	Optimization of transcription factor binding map accuracy utilizing knockout-mouse models.
Academic Article	Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Academic Article	The inflammasomes and autoinflammatory syndromes.
Academic Article	Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
Academic Article	Danger signaling in atherosclerosis.
Academic Article	A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Academic Article	Innate immunity in Alzheimer's disease.
Academic Article	Neuroinflammation in Alzheimer's disease.
Academic Article	Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
Academic Article	Innate immune memory: a paradigm shift in understanding host defense.
Academic Article	A transcriptional perspective on human macrophage biology.
Academic Article	TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article	CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.
Academic Article	ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article	Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology.
Academic Article	Trained immunity: A program of innate immune memory in health and disease.
Academic Article	Crystal Formation in Inflammation.
Academic Article	Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article	Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.
Academic Article	Interferons and inflammasomes: Cooperation and counterregulation in disease.
Academic Article	Long-term activation of the innate immune system in atherosclerosis.
Academic Article	TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.
Academic Article	An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in?mice.
Academic Article	Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
Academic Article	Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article	Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.
Academic Article	HMGB1, IL-1a, IL-33 and S100 proteins: dual-function alarmins.
Academic Article	RAGE Enhances TLR Responses through Binding and Internalization of RNA.
Academic Article	Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Academic Article	TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Academic Article	Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Academic Article	Generation of Innate Immune Reporter Cells Using Retroviral Transduction.
Academic Article	ASC specks: a biomarker for myelodysplastic syndromes?
Academic Article	A guiding map for inflammation.
Academic Article	Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.
Academic Article	The intra- and extracellular functions of ASC specks.
Academic Article	Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Academic Article	Immortalization of Murine Bone Marrow-Derived Macrophages.
Academic Article	The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article	Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.
Academic Article	Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Academic Article	Innate Immunity and Neurodegeneration.
Academic Article	Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients.
Academic Article	Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Academic Article	PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy.
Academic Article	NLRP3 inflammasome activation in inflammaging.
Academic Article	Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Academic Article	CD14-New Tricks of an Old Acquaintance.
Academic Article	Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control.
Academic Article	Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages.
Academic Article	DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways.
Academic Article	Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis.
Academic Article	The Western lifestyle has lasting effects on metaflammation.
Academic Article	Alternative splicing regulates stochastic NLRP3 activity.
Academic Article	AIM2 inflammasome-derived IL-1? induces postoperative ileus in mice.
Academic Article	High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response.
Academic Article	Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
Academic Article	Western Diet and the Immune System: An Inflammatory Connection.
Academic Article	Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Academic Article	Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Academic Article	Defining trained immunity and its role in health and disease.
Academic Article	Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Academic Article	Jack of all trades inhibits inflammation (in sober people).
Academic Article	The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
Academic Article	Author Correction: A guiding map for inflammation.
Academic Article	Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article	Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis.
Academic Article	Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury.
Academic Article	Necroptosis, pyroptosis and apoptosis: an intricate game of cell death.
Academic Article	Cytosolic d-type CpG-oligonucleotides induce a type I interferon response by activating the cGAS-STING signaling pathway.
Academic Article	Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters.
Academic Article	Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article	Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article	Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.
Academic Article	Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies.
Academic Article	Early IFN-a signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Academic Article	The inflammasome: from bench to bedside.
Academic Article	Deciphering How NLRP3 Incites the Stromal Response in Kawasaki Vasculitis.
Concept	Enzyme-Linked Immunospot Assay
Concept	Immunity, Heterologous
Academic Article	Primary cilia and their effects on immune cell functions and metabolism: a model.
Academic Article	Immune response in COVID-19: what is next?
Academic Article	Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Academic Article	How location and cellular signaling combine to activate the NLRP3 inflammasome.
Academic Article	Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form.

Search Criteria

Immune
syndromes