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Latz, Eicke
One or more keywords matched the following items that are connected to
Latz, Eicke
Item Type
Name
Academic Article
Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Academic Article
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article
ASC speck formation as a readout for inflammasome activation.
Academic Article
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article
Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Academic Article
Rational design of immunostimulatory siRNAs.
Academic Article
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article
HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro.
Academic Article
Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Academic Article
Assessment and quantification of crystal-induced lysosomal damage.
Concept
Macrophage Activation
Concept
Macrophages
Concept
Granulocyte-Macrophage Colony-Stimulating Factor
Concept
Macrophages, Peritoneal
Concept
Macrophage-1 Antigen
Concept
Macrophage Colony-Stimulating Factor
Academic Article
HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages.
Academic Article
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.
Academic Article
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Academic Article
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Academic Article
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article
LOX-1 and mitochondria: an inflammatory relationship.
Academic Article
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
Academic Article
A transcriptional perspective on human macrophage biology.
Academic Article
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article
Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article
CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.
Academic Article
ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Academic Article
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Academic Article
Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.
Academic Article
Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.
Academic Article
Soluble Uric Acid Activates the NLRP3 Inflammasome.
Academic Article
Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Academic Article
RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In?Vivo.
Academic Article
Generation of Innate Immune Reporter Cells Using Retroviral Transduction.
Academic Article
Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
Academic Article
Immortalization of Murine Bone Marrow-Derived Macrophages.
Academic Article
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article
Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.
Academic Article
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
Academic Article
Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids.
Academic Article
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Academic Article
TAK1ng control: TAK1 restrains NLRP3 activation.
Academic Article
Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages.
Academic Article
NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.
Academic Article
Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.
Academic Article
Alternative splicing regulates stochastic NLRP3 activity.
Academic Article
CD82 controls CpG-dependent TLR9 signaling.
Academic Article
Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Academic Article
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.
Academic Article
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article
The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
Academic Article
Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid.
Academic Article
Sensing soluble uric acid by Naip1-Nlrp3 platform.
Academic Article
Cytosolic d-type CpG-oligonucleotides induce a type I interferon response by activating the cGAS-STING signaling pathway.
Academic Article
Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article
Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.
Academic Article
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
Academic Article
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Academic Article
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
Academic Article
Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation.
Academic Article
Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation.
Academic Article
Cutting Edge: STING Induces ACLY Activation and Metabolic Adaptations in Human Macrophages through TBK1.
Academic Article
Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Search Criteria
Macrophage