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Academic Article IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article The LPS receptor generates inflammatory signals from the cell surface.
Academic Article Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Academic Article The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells.
Academic Article TLR9 and the recognition of self and non-self nucleic acids.
Academic Article Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Academic Article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
Academic Article SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Academic Article Efficacy and safety of chaperonin 10 in patients with moderate to severe plaque psoriasis: evidence of utility beyond a single indication.
Academic Article The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.
Academic Article RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.
Academic Article Phosphothioate oligodeoxynucleotides inhibit Plasmodium sporozoite gliding motility.
Academic Article Intracellular DNA recognition.
Academic Article The sterile inflammatory response.
Academic Article Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Academic Article NOX-free inflammasome activation.
Academic Article IFI16 is an innate immune sensor for intracellular DNA.
Academic Article The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Academic Article Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
Academic Article Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
Academic Article Innate immune receptors for nucleic acids.
Academic Article Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair.
Academic Article KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Academic Article For gut's sake: NLRC4 inflammasomes distinguish friend from foe.
Academic Article Endothelial microparticle uptake in target cells is annexin I/phosphatidylserine receptor dependent and prevents apoptosis.
Academic Article Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.
Academic Article CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?
Academic Article ASC speck formation as a readout for inflammasome activation.
Academic Article The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Academic Article LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article Receptor "cross talk" in innate immunity.
Academic Article Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Academic Article TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article Mechanisms of TLR9 activation.
Academic Article Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
Academic Article The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Academic Article Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Academic Article Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Academic Article Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
Academic Article AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Academic Article Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution.
Academic Article Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Academic Article Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.
Academic Article Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides.
Academic Article Inflammasomes: too big to miss.
Academic Article The inflammasomes: mechanisms of activation and function.
Academic Article Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Academic Article Rational design of immunostimulatory siRNAs.
Academic Article Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy.
Academic Article Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.
Academic Article Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens.
Academic Article Intracellular sensing of microbes and danger signals by the inflammasomes.
Academic Article HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro.
Academic Article Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Academic Article Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article IL-1, quo vadis?
Academic Article PKR stirs up inflammasomes.
Academic Article Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Academic Article iGLuc: a luciferase-based inflammasome and protease activity reporter.
Academic Article Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Academic Article Activation and regulation of the inflammasomes.
Academic Article Assessment and quantification of crystal-induced lysosomal damage.
Academic Article Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Concept Receptors, Chemokine
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Academic Article HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages.
Academic Article Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.
Academic Article RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Academic Article Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.
Academic Article Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Academic Article Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Academic Article NLRC3 puts the brakes on STING.
Academic Article Innate immune activation in neurodegenerative disease.
Academic Article The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article LOX-1 and mitochondria: an inflammatory relationship.
Academic Article The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
Academic Article OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines.
Academic Article Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Academic Article Inflammasome activation in response to dead cells and their metabolites.
Academic Article Optimization of transcription factor binding map accuracy utilizing knockout-mouse models.
Academic Article Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Academic Article The inflammasomes and autoinflammatory syndromes.
Academic Article Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
Academic Article NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1?.
Academic Article Synergistic activation of Toll-like receptor 8 by two RNA degradation products.
Academic Article A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Academic Article Neuroinflammation in Alzheimer's disease.
Academic Article Neutrophil extracellular trap formation in supragingival biofilms.
Academic Article Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
Academic Article A transcriptional perspective on human macrophage biology.
Academic Article Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage.
Academic Article TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article Weekly Treatment of 2-Hydroxypropyl-?-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice.
Academic Article Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.
Academic Article ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.
Academic Article Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology.
Academic Article Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Academic Article Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET.
Academic Article Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Academic Article Crystal Formation in Inflammation.
Academic Article Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.
Academic Article A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In?Vivo Infection.
Academic Article Long-term activation of the innate immune system in atherosclerosis.
Academic Article TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.
Academic Article Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.
Academic Article An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in?mice.
Academic Article Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
Academic Article Automated nanoscale flow cytometry for assessing protein-protein interactions.
Academic Article Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article IRGB10 Exposes Bacteria's Intimate Secrets.
Academic Article Assembly and regulation of ASC specks.
Academic Article Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.
Academic Article Statins improve NASH via inhibition of RhoA and Ras.
Academic Article HMGB1, IL-1a, IL-33 and S100 proteins: dual-function alarmins.
Academic Article RAGE Enhances TLR Responses through Binding and Internalization of RNA.
Academic Article Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
Academic Article PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.
Academic Article Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.
Academic Article Soluble Uric Acid Activates the NLRP3 Inflammasome.
Academic Article Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Academic Article TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Academic Article NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
Academic Article Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Academic Article Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Academic Article Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Academic Article RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In?Vivo.
Academic Article Generation of Innate Immune Reporter Cells Using Retroviral Transduction.
Academic Article Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
Academic Article ASC specks: a biomarker for myelodysplastic syndromes?
Academic Article Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
Academic Article A guiding map for inflammation.
Academic Article Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.
Academic Article The intra- and extracellular functions of ASC specks.
Academic Article Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Academic Article Immortalization of Murine Bone Marrow-Derived Macrophages.
Academic Article The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.
Academic Article Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Academic Article Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality.
Academic Article Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
Academic Article Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids.
Academic Article Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients.
Academic Article Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Academic Article Circulating microbiome in blood of different circulatory compartments.
Academic Article PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy.
Academic Article TAK1ng control: TAK1 restrains NLRP3 activation.
Academic Article Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Academic Article The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Academic Article CD14-New Tricks of an Old Acquaintance.
Academic Article Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells.
Academic Article Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control.
Academic Article Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages.
Academic Article DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways.
Academic Article Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells.
Academic Article Author Correction: Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis.
Academic Article Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.
Academic Article Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency.
Academic Article NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.
Academic Article Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.
Academic Article Alternative splicing regulates stochastic NLRP3 activity.
Academic Article AIM2 inflammasome-derived IL-1? induces postoperative ileus in mice.
Academic Article High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response.
Academic Article Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome.
Academic Article CD82 controls CpG-dependent TLR9 signaling.
Academic Article Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
Academic Article NLRP3 inflammasome activation drives tau pathology.
Academic Article Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Academic Article Defining trained immunity and its role in health and disease.
Academic Article PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
Academic Article ?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
Academic Article Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Academic Article Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.
Academic Article Immediate and long-term consequences of COVID-19 infections for the development of neurological disease.
Academic Article Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.
Academic Article Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
Academic Article STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury.
Academic Article The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
Academic Article Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
Academic Article Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
Academic Article The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles.
Academic Article Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.
Academic Article Author Correction: A guiding map for inflammation.
Academic Article Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid.
Academic Article Sensing soluble uric acid by Naip1-Nlrp3 platform.
Academic Article Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis.
Academic Article Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury.
Academic Article Necroptosis, pyroptosis and apoptosis: an intricate game of cell death.
Academic Article N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection.
Academic Article Cytosolic d-type CpG-oligonucleotides induce a type I interferon response by activating the cGAS-STING signaling pathway.
Academic Article Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters.
Academic Article Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article Development of Fluorescent and Biotin Probes Targeting NLRP3.
Academic Article Contact-dependent inhibition of HIV-1 replication in ex?vivo human tonsil cultures by polymorphonuclear neutrophils.
Academic Article Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis.
Academic Article Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.
Academic Article CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling.
Academic Article IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice.
Academic Article Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies.
Academic Article The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.
Academic Article Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Academic Article Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Academic Article BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Academic Article Early IFN-a signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Academic Article The inflammasome: from bench to bedside.
Academic Article The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.
Academic Article Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Academic Article Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease.
Academic Article Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
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Academic Article NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease.
Academic Article Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.
Academic Article Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1.
Academic Article New Aspects of Kidney Fibrosis-From Mechanisms of Injury to Modulation of Disease.
Academic Article Primary cilia and their effects on immune cell functions and metabolism: a model.
Academic Article Natural Killer Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Against SARS-CoV-2 After Natural Infection Is More Potent Than After Vaccination.
Academic Article Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.
Academic Article Immune response in COVID-19: what is next?
Academic Article Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Academic Article Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment.
Academic Article Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles.
Academic Article Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
Academic Article P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection.
Academic Article ATP-binding and hydrolysis of human NLRP3.
Academic Article How location and cellular signaling combine to activate the NLRP3 inflammasome.
Academic Article Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study.
Academic Article Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Academic Article Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Academic Article Mitochondrial damage activates the NLRP10 inflammasome.
Academic Article Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation.
Academic Article SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Academic Article NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing.
Academic Article CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.
Academic Article Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis.
Academic Article PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Academic Article Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation.
Academic Article Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation.
Academic Article NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing.
Academic Article UNC93B1 variants underlie TLR7-dependent autoimmunity.
Academic Article Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Academic Article Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model.
Academic Article SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Academic Article Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
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