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Latz, Eicke

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Item Type	Name
Academic Article	Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.
Academic Article	Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article	The LPS receptor generates inflammatory signals from the cell surface.
Academic Article	Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection.
Academic Article	Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells.
Academic Article	TLR9 and the recognition of self and non-self nucleic acids.
Academic Article	Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Academic Article	Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article	The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
Academic Article	SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Academic Article	Efficacy and safety of chaperonin 10 in patients with moderate to severe plaque psoriasis: evidence of utility beyond a single indication.
Academic Article	The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article	Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article	TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA.
Academic Article	An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.
Academic Article	RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.
Academic Article	Phosphothioate oligodeoxynucleotides inhibit Plasmodium sporozoite gliding motility.
Academic Article	Intracellular DNA recognition.
Academic Article	The sterile inflammatory response.
Academic Article	Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Academic Article	NOX-free inflammasome activation.
Academic Article	IFI16 is an innate immune sensor for intracellular DNA.
Academic Article	The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Academic Article	Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
Academic Article	Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
Academic Article	Innate immune receptors for nucleic acids.
Academic Article	Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair.
Academic Article	KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Academic Article	For gut's sake: NLRC4 inflammasomes distinguish friend from foe.
Academic Article	Endothelial microparticle uptake in target cells is annexin I/phosphatidylserine receptor dependent and prevents apoptosis.
Academic Article	Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Academic Article	A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
Academic Article	NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article	Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.
Academic Article	Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.
Academic Article	CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article	IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?
Academic Article	ASC speck formation as a readout for inflammasome activation.
Academic Article	The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism.
Academic Article	Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Academic Article	LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article	Receptor "cross talk" in innate immunity.
Academic Article	Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Academic Article	TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article	Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article	Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article	Mechanisms of TLR9 activation.
Academic Article	Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article	Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
Academic Article	The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
Academic Article	HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Academic Article	Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.
Academic Article	Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Academic Article	Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Academic Article	Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
Academic Article	AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Academic Article	Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution.
Academic Article	Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article	Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Academic Article	Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist.
Academic Article	Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides.
Academic Article	Inflammasomes: too big to miss.
Academic Article	The inflammasomes: mechanisms of activation and function.
Academic Article	Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Academic Article	Rational design of immunostimulatory siRNAs.
Academic Article	Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy.
Academic Article	Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article	The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article	NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article	Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.
Academic Article	Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article	Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens.
Academic Article	Intracellular sensing of microbes and danger signals by the inflammasomes.
Academic Article	HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro.
Academic Article	Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Academic Article	Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article	IL-1, quo vadis?
Academic Article	PKR stirs up inflammasomes.
Academic Article	Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Academic Article	Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Academic Article	iGLuc: a luciferase-based inflammasome and protease activity reporter.
Academic Article	Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Academic Article	Activation and regulation of the inflammasomes.
Academic Article	Assessment and quantification of crystal-induced lysosomal damage.
Academic Article	Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.
Concept	Receptors, Chemokine
Concept	Epithelial Cells
Concept	Protein Binding
Concept	Receptors, Interleukin-1
Concept	Staphylococcus aureus
Concept	Anti-Bacterial Agents
Concept	Brain Neoplasms
Concept	DNA-Binding Proteins
Concept	Amyloid beta-Protein Precursor
Concept	Interferon-beta
Concept	Bone Resorption
Concept	Mycobacterium tuberculosis
Concept	Blood Pressure
Concept	Receptors, LDL
Concept	Receptors, IgG
Concept	Cell Lineage
Concept	Software
Concept	Humans
Concept	Animals, Newborn
Concept	Receptors, Antigen, T-Cell
Concept	Phosphate-Binding Proteins
Concept	Brain
Concept	Aged, 80 and over
Concept	HeLa Cells
Concept	Cell Nucleus
Concept	Blood Vessels
Concept	Microfilariae
Concept	Bordetella parapertussis
Concept	Cell Communication
Concept	Receptor, Interferon alpha-beta
Concept	Plasmodium
Concept	Mice, Inbred BALB C
Concept	Cell Degranulation
Concept	Body Weight
Concept	Mice, Obese
Concept	Prions
Concept	Influenza A Virus, H1N1 Subtype
Concept	Alcohol Drinking
Concept	Cell Survival
Concept	Receptors, Cell Surface
Concept	Kupffer Cells
Concept	Brefeldin A
Concept	Schistosoma mansoni
Concept	Toll-Like Receptors
Concept	Bone Marrow Transplantation
Concept	Cell Wall
Concept	HIV-1
Concept	BALB 3T3 Cells
Concept	Cricetinae
Concept	Receptors, Mitogen
Concept	Bacterial Toxins
Concept	Macaca
Concept	Dogs
Concept	Animals
Concept	Herpesvirus 1, Human
Concept	Biological Assay
Concept	Aged
Concept	Dendritic Cells
Concept	Chronic Disease
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Double-Blind Method
Concept	Cell Cycle Proteins
Concept	Protein Biosynthesis
Concept	Biopolymers
Concept	Mice, Knockout
Concept	Endothelial Cells
Concept	BCG Vaccine
Concept	Receptors, Interleukin-1 Type I
Concept	Mice, Inbred C3H
Concept	Blood Cells
Concept	Cell-Derived Microparticles
Concept	Adolescent
Concept	CHO Cells
Concept	Blotting, Western
Concept	Neisseria meningitidis
Concept	Butyrates
Concept	Bacterial Translocation
Concept	Bacterial Physiological Phenomena
Concept	Tumor Stem Cell Assay
Concept	Receptors, Pattern Recognition
Concept	Cricetulus
Concept	Plants
Concept	Invertebrates
Concept	Biomarkers
Concept	Poxviridae
Concept	Scavenger Receptors, Class A
Concept	RNA, Bacterial
Concept	Antibodies, Bacterial
Concept	Mice
Concept	Cell Differentiation
Concept	Cell Line, Transformed
Concept	Bone Marrow Cells
Concept	Models, Biological
Concept	rhoA GTP-Binding Protein
Concept	Biological Transport, Active
Concept	Bordetella Infections
Concept	Antibody-Dependent Cell Cytotoxicity
Concept	B7-2 Antigen
Concept	Behavior, Animal
Concept	Cryptococcus neoformans
Concept	rab GTP-Binding Proteins
Concept	Biofilms
Concept	Dengue Virus
Concept	Adult
Concept	Mice, Inbred C57BL
Concept	Computational Biology
Concept	Bacillus anthracis
Concept	Bronchoalveolar Lavage Fluid
Concept	Cell Movement
Concept	Influenza A Virus, H3N2 Subtype
Concept	Cells, Cultured
Concept	Pneumonia, Bacterial
Concept	Blood Platelets
Concept	Mice, Transgenic
Concept	Cell Separation
Concept	Antigens, Bacterial
Concept	DNA Viruses
Concept	Biomedical Research
Concept	Biotinylation
Concept	Cell Proliferation
Concept	Simian Immunodeficiency Virus
Concept	DNA, Bacterial
Concept	Biological Transport
Concept	Escherichia coli
Concept	RNA Viruses
Concept	Macaca mulatta
Concept	Biosensing Techniques
Concept	DEAD-box RNA Helicases
Concept	Candida
Concept	Cell Death
Concept	Active Transport, Cell Nucleus
Concept	Vaccinia virus
Concept	Brain Injuries
Concept	Mannose-Binding Lectins
Concept	Mice, Inbred NOD
Concept	Trypanosoma cruzi
Concept	Blood Glucose
Concept	Scavenger Receptors, Class E
Concept	Receptors, Odorant
Concept	Friends
Concept	Life Style
Concept	beta-Cyclodextrins
Concept	Cell Membrane
Concept	Cell Membrane Structures
Concept	ATP-Binding Cassette Transporters
Concept	Spores, Bacterial
Concept	Retroviridae
Concept	Lipopolysaccharide Receptors
Concept	Models, Animal
Concept	Bacterial Proteins
Concept	Cell Culture Techniques
Concept	Bystander Effect
Concept	Calcium-Binding Proteins
Concept	Bacterial Outer Membrane Proteins
Concept	Bordetella bronchiseptica
Concept	Scavenger Receptors, Class B
Concept	Clone Cells
Concept	Pseudomonas aeruginosa
Concept	Receptors, Cytokine
Concept	K562 Cells
Concept	Systems Biology
Concept	Binding Sites
Concept	Francisella tularensis
Concept	Mice, Nude
Concept	Receptors, Glucocorticoid
Concept	Mice, Inbred Strains
Concept	Sporozoites
Concept	Streptococcus pyogenes
Concept	Antigen-Presenting Cells
Concept	Rats
Concept	Receptors, Immunologic
Concept	Autoimmunity
Concept	Receptors, Interleukin
Concept	Inflammatory Bowel Diseases
Concept	Germ-Free Life
Concept	Bacterial Infections
Concept	Cell Line
Concept	Breast Neoplasms
Concept	B-Lymphocytes
Concept	Influenza A virus
Concept	Middle Aged
Concept	Chimera
Concept	Binge-Eating Disorder
Concept	Filarioidea
Concept	Plasmodium falciparum
Concept	Swine
Concept	Bacteria
Concept	Receptors, Tumor Necrosis Factor
Concept	Genetic Vectors
Concept	Bordetella pertussis
Concept	Receptors, Antigen, B-Cell
Concept	Young Adult
Concept	Streptococcus agalactiae
Concept	Blood Proteins
Concept	Myeloid Cells
Concept	Base Sequence
Concept	Killer Cells, Natural
Concept	Amyloid beta-Peptides
Concept	Plasmodium berghei
Concept	Salmonella typhimurium
Concept	Listeria monocytogenes
Concept	HIV
Concept	Cytomegalovirus
Concept	Mice, Mutant Strains
Concept	Cell Line, Tumor
Concept	Receptors, Cytoplasmic and Nuclear
Concept	RNA-Binding Proteins
Concept	Polysaccharides, Bacterial
Academic Article	HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages.
Academic Article	Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.
Academic Article	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article	High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Academic Article	Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Academic Article	Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article	Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.
Academic Article	Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Academic Article	Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Academic Article	NLRC3 puts the brakes on STING.
Academic Article	Innate immune activation in neurodegenerative disease.
Academic Article	The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article	LOX-1 and mitochondria: an inflammatory relationship.
Academic Article	The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
Academic Article	OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines.
Academic Article	Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Academic Article	Inflammasome activation in response to dead cells and their metabolites.
Academic Article	Optimization of transcription factor binding map accuracy utilizing knockout-mouse models.
Academic Article	Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Academic Article	The inflammasomes and autoinflammatory syndromes.
Academic Article	Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
Academic Article	NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1?.
Academic Article	Synergistic activation of Toll-like receptor 8 by two RNA degradation products.
Academic Article	A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Academic Article	Neuroinflammation in Alzheimer's disease.
Academic Article	Neutrophil extracellular trap formation in supragingival biofilms.
Academic Article	Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
Academic Article	A transcriptional perspective on human macrophage biology.
Academic Article	Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage.
Academic Article	TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Academic Article	Weekly Treatment of 2-Hydroxypropyl-?-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice.
Academic Article	Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article	CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.
Academic Article	ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article	Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.
Academic Article	Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology.
Academic Article	Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.
Academic Article	Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET.
Academic Article	Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Academic Article	Crystal Formation in Inflammation.
Academic Article	Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article	Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.
Academic Article	A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In?Vivo Infection.
Academic Article	Long-term activation of the innate immune system in atherosclerosis.
Academic Article	TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.
Academic Article	Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.
Academic Article	An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in?mice.
Academic Article	Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
Academic Article	Automated nanoscale flow cytometry for assessing protein-protein interactions.
Academic Article	Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.
Academic Article	IRGB10 Exposes Bacteria's Intimate Secrets.
Academic Article	Assembly and regulation of ASC specks.
Academic Article	Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.
Academic Article	Statins improve NASH via inhibition of RhoA and Ras.
Academic Article	HMGB1, IL-1a, IL-33 and S100 proteins: dual-function alarmins.
Academic Article	RAGE Enhances TLR Responses through Binding and Internalization of RNA.
Academic Article	Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
Academic Article	PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.
Academic Article	Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.
Academic Article	Soluble Uric Acid Activates the NLRP3 Inflammasome.
Academic Article	Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Academic Article	TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Academic Article	NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
Academic Article	Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Academic Article	Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Academic Article	Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Academic Article	RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In?Vivo.
Academic Article	Generation of Innate Immune Reporter Cells Using Retroviral Transduction.
Academic Article	Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
Academic Article	ASC specks: a biomarker for myelodysplastic syndromes?
Academic Article	Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.
Academic Article	A guiding map for inflammation.
Academic Article	Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article	Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.
Academic Article	The intra- and extracellular functions of ASC specks.
Academic Article	Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Academic Article	Immortalization of Murine Bone Marrow-Derived Macrophages.
Academic Article	The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article	Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.
Academic Article	Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Academic Article	Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality.
Academic Article	Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
Academic Article	Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids.
Academic Article	Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients.
Academic Article	Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Academic Article	Circulating microbiome in blood of different circulatory compartments.
Academic Article	PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy.
Academic Article	TAK1ng control: TAK1 restrains NLRP3 activation.
Academic Article	Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Academic Article	The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Academic Article	CD14-New Tricks of an Old Acquaintance.
Academic Article	Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells.
Academic Article	Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control.
Academic Article	Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages.
Academic Article	DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways.
Academic Article	Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells.
Academic Article	Author Correction: Inflammasome signalling in brain function and neurodegenerative disease.
Academic Article	Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis.
Academic Article	Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.
Academic Article	Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency.
Academic Article	NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.
Academic Article	Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.
Academic Article	Alternative splicing regulates stochastic NLRP3 activity.
Academic Article	AIM2 inflammasome-derived IL-1? induces postoperative ileus in mice.
Academic Article	High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response.
Academic Article	Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome.
Academic Article	CD82 controls CpG-dependent TLR9 signaling.
Academic Article	Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
Academic Article	NLRP3 inflammasome activation drives tau pathology.
Academic Article	Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Academic Article	Defining trained immunity and its role in health and disease.
Academic Article	PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
Academic Article	?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
Academic Article	Platelets Fuel the Inflammasome Activation of Innate Immune Cells.
Academic Article	Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.
Academic Article	Immediate and long-term consequences of COVID-19 infections for the development of neurological disease.
Academic Article	Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.
Academic Article	Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
Academic Article	STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression.
Academic Article	Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury.
Academic Article	The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.
Academic Article	Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
Academic Article	Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
Academic Article	The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles.
Academic Article	Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.
Academic Article	Author Correction: A guiding map for inflammation.
Academic Article	Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article	Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid.
Academic Article	Sensing soluble uric acid by Naip1-Nlrp3 platform.
Academic Article	Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis.
Academic Article	Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury.
Academic Article	Necroptosis, pyroptosis and apoptosis: an intricate game of cell death.
Academic Article	N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection.
Academic Article	Cytosolic d-type CpG-oligonucleotides induce a type I interferon response by activating the cGAS-STING signaling pathway.
Academic Article	Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters.
Academic Article	Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Academic Article	Development of Fluorescent and Biotin Probes Targeting NLRP3.
Academic Article	Contact-dependent inhibition of HIV-1 replication in ex?vivo human tonsil cultures by polymorphonuclear neutrophils.
Academic Article	Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.
Academic Article	Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis.
Academic Article	Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.
Academic Article	CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling.
Academic Article	IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice.
Academic Article	Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies.
Academic Article	The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.
Academic Article	Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Academic Article	Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Academic Article	BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Academic Article	Early IFN-a signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Academic Article	The inflammasome: from bench to bedside.
Academic Article	The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis.
Academic Article	Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
Academic Article	Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease.
Academic Article	Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
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Academic Article	NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease.
Academic Article	Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.
Academic Article	Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1.
Academic Article	New Aspects of Kidney Fibrosis-From Mechanisms of Injury to Modulation of Disease.
Academic Article	Primary cilia and their effects on immune cell functions and metabolism: a model.
Academic Article	Natural Killer Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Against SARS-CoV-2 After Natural Infection Is More Potent Than After Vaccination.
Academic Article	Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.
Academic Article	Immune response in COVID-19: what is next?
Academic Article	Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Academic Article	Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment.
Academic Article	Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles.
Academic Article	Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
Academic Article	P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection.
Academic Article	ATP-binding and hydrolysis of human NLRP3.
Academic Article	How location and cellular signaling combine to activate the NLRP3 inflammasome.
Academic Article	Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study.
Academic Article	Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Academic Article	Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Academic Article	Mitochondrial damage activates the NLRP10 inflammasome.
Academic Article	Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation.
Academic Article	SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Academic Article	NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing.
Academic Article	CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.
Academic Article	Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis.
Academic Article	PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Academic Article	Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation.
Academic Article	Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation.
Academic Article	NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing.
Academic Article	UNC93B1 variants underlie TLR7-dependent autoimmunity.
Academic Article	Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Academic Article	Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model.
Academic Article	SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Academic Article	NLRP3 inflammasome signalling in Alzheimer's disease.
Academic Article	Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Academic Article	Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies.
Academic Article	From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.
Academic Article	Topical application of a CCL22-binding aptamer suppresses contact allergy.
Academic Article	Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice.
Academic Article	Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.
Academic Article	Prospective Cytokine Profiling in Aqueous Humor Reveals a Proinflammatory Microenvironment in Highly Dense Nuclear Cataracts.
Academic Article	ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.
Academic Article	NIS-Seq enables cell-type-agnostic optical perturbation screening.
Academic Article	Systematic assessment of COVID-19 host genetics using whole genome sequencing data.
Academic Article	Litomosoides sigmodontis microfilariae-induced eosinophil ETosis is dependent on the canonical inflammasome pathway.
Academic Article	RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells.
Academic Article	NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.
Academic Article	Neuroinflammation and immunometabolism in neurodegenerative diseases.
Academic Article	Mutational landscape and impact of clonal hematopoiesis of indeterminate potential in severe aortic valve stenosis.

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