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One or more keywords matched the following properties of Khan, Ashraf
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Academic Background:

MBBSJN Medical College, Aligarh University, Aligarh, INDIA

MDPathology, JN Medical College, Aligarh University, Aligarh, INDIA

ResidencyHistopathology, Lewisham & Guy’s Hospital, University of London, London, UK

FRCPath Histopathology, Royal College of Pathologists, London, UK

Fellowship Surgical Pathology, University of Massachusetts Medical Center, Worcester, MA

Dr. Khan's pictureResearch Interests:

Dr. Ashraf Khan’s clinical interest includes diagnostic surgical pathology of Breast and Endocrine system. Dr. Khan is actively involved in clinical translational research focused in the field of thyroid and breast cancer investigating biomarkers that help in the diagnosis and prediction of outcome in these tumors. Over the past decade Dr. Khan has published several papers on the role of cell cycle regulatory proteins, translation initiation factors and cell adhesion molecules in the diagnosis of thyroid follicular tumors and progression of thyroid cancer. Dr. Khan was a key contributor of one large multi-institution international study published in The Lancet on the role of galectin 3 and CD44 in the diagnosis of thyroid malignancy. Dr. Khan’s collaboration with the basic scientists in the department of cancer biology at UMass has resulted in multiple projects includingb4-integrin signature in basal-like breast cancer which was recently published and Sox-9 expression in breast cancer which is work in progress. In addition Dr. Khan is a PI on a Department of Defense Grant in collaboration with Dr. Leslie Shaw in department of cancer biology looking at the Insulin Receptor Substrate Proteins (IRS1 and IRS2) in breast cancer with special focus on potential role they may play in Herceptin resistance in HER-2 positive breast cancer. He is also currently involved in studying the micro RNA signature in breast cancer especially estrogen receptor positive node negative tumors with potential therapeutic implications. Dr. Khan is a member of the UMASS graduate school of biomedical sciences representing cancer biology.

Dr. Khan is the past President and Secretary of the Endocrine Pathology Society, a companion society of the US and Canadian Academy of Pathology. He is a reviewer for a number of pathology and endocrinology journals, serves on the editorial board of the journal Endocrine Pathology and is the Section Editor (Endocrine Pathology) of the Archives of Pathology and Laboratory Medicine. In addition to numerous original articles, Dr. Khan has authored many book chapters and invited reviews and is currently editing a text book on surgical pathology of endocrine tumors.

One or more keywords matched the following items that are connected to Khan, Ashraf
Item TypeName
Academic Article Mammaglobin and CRxA-01 in pleural effusion cytology: potential utility of distinguishing metastatic breast carcinomas from other cytokeratin 7-positive/cytokeratin 20-negative carcinomas.
Academic Article HER-2 status in breast cancer: correlation of gene amplification by FISH with immunohistochemistry expression using advanced cellular imaging system.
Academic Article A novel breast cancer cell line initially established from pleural effusion: evolution towards a more aggressive phenotype.
Academic Article Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance.
Academic Article A functional Notch-survivin gene signature in basal breast cancer.
Academic Article IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype.
Academic Article Pseudoangiomatous stromal hyperplasia: an overview.
Academic Article Effects of ?4 integrin expression on microRNA patterns in breast cancer.
Academic Article Cell blocks of breast FNAs frequently allow diagnosis of invasion or histological classification of proliferative changes.
Academic Article The role of sentinel lymph node biopsy in the management of breast cancer.
Academic Article Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer.
Academic Article Effective role of hormonal therapy in metastatic primary neuroendocrine breast carcinoma.
Academic Article Effect of Paget's disease on survival in breast cancer: an exploratory study.
Academic Article Multimodal optical imaging for detecting breast cancer.
Academic Article Metastatic carcinoma to the thyroid gland: a single institution 20-year experience and review of the literature.
Concept Breast Neoplasms
Academic Article Diagnostic role of immunohistochemistry in the evaluation of breast pathology specimens.
Academic Article Fibroepithelial tumors of the breast: pathologic and immunohistochemical features and molecular mechanisms.
Academic Article Basal-like breast cancer: update on clinicopathologic, immunohistochemical, and molecular features.
Academic Article Theranostic and molecular classification of breast cancer.
Academic Article The ever-changing role of sentinel lymph node biopsy in the management of breast cancer.
Academic Article Polarization-sensitive multimodal imaging for detecting breast cancer.
Academic Article The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast.
Academic Article Diagnosis of Metaplastic Breast Carcinoma: Keratin OSCAR Versus Other Cytokeratins.
Academic Article Feasibility demonstration of frequency domain terahertz imaging in breast cancer margin determination.
Academic Article Translational Potential of Fluorescence Polarization for Breast Cancer Cytopathology.
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  • Breast Neoplasms