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Kelch, Brian

One or more keywords matched the following items that are connected to Kelch, Brian

Item Type	Name
Academic Article	The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Academic Article	How a DNA polymerase clamp loader opens a sliding clamp.
Academic Article	Functional modulation of a protein folding landscape via side-chain distortion.
Academic Article	The 0.83 A resolution crystal structure of alpha-lytic protease reveals the detailed structure of the active site and identifies a source of conformational strain.
Academic Article	Mediation by indole analogues of electron transfer during oxygen activation in variants of Escherichia coli ribonucleotide reductase R2 lacking the electron-shuttling tryptophan 48.
Academic Article	Structural and mechanistic exploration of acid resistance: kinetic stability facilitates evolution of extremophilic behavior.
Academic Article	Mesophile versus thermophile: insights into the structural mechanisms of kinetic stability.
Academic Article	Clamp loader ATPases and the evolution of DNA replication machinery.
Academic Article	A structural role for the PHP domain in E. coli DNA polymerase III.
Concept	Viral Tail Proteins
Concept	Protein Binding
Concept	Protein Subunits
Concept	DNA-Binding Proteins
Concept	Protein Folding
Concept	Protein Processing, Post-Translational
Concept	MutS Homolog 2 Protein
Concept	Fanconi Anemia Complementation Group Proteins
Concept	Carrier Proteins
Concept	Cell Cycle Proteins
Concept	Protein Interaction Mapping
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Mutant Proteins
Concept	Protein Denaturation
Concept	Viral Proteins
Concept	Proteins
Concept	Protein Structure, Secondary
Concept	BRCA1 Protein
Concept	Cytoskeletal Proteins
Concept	Protein Structure, Tertiary
Concept	Replication Protein C
Concept	Protein Multimerization
Concept	Crystallography, X-Ray
Concept	Escherichia coli Proteins
Concept	Bacterial Proteins
Concept	Capsid Proteins
Concept	Protein Stability
Concept	Protein Structure, Quaternary
Concept	Saccharomyces cerevisiae Proteins
Concept	Drosophila Proteins
Concept	Calcium-Calmodulin-Dependent Protein Kinase Type 2
Concept	Protein Conformation
Concept	Tumor Suppressor Proteins
Academic Article	The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Academic Article	Structure and mechanism of the ATPase that powers viral genome packaging.
Academic Article	A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
Academic Article	Review: The lord of the rings: Structure and mechanism of the sliding clamp loader.
Academic Article	The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.
Academic Article	Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.
Academic Article	Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
Academic Article	A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.
Academic Article	Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Academic Article	Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.
Academic Article	A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry.
Academic Article	Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch.
Academic Article	Exploring the Evolutionary History of Kinetic Stability in the a-Lytic Protease Family.
Academic Article	Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1.
Academic Article	Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor.
Concept	Protein Domains
Concept	Protein Conformation, alpha-Helical
Concept	MutS Homolog 3 Protein
Concept	LIM Domain Proteins
Academic Article	Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Academic Article	A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Academic Article	CaMKII binds both substrates and activators at the active site.
Academic Article	Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage.
Academic Article	Conformational dynamics control assembly of an extremely long bacteriophage tail tube.
Academic Article	A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
Academic Article	Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
Academic Article	Capsid transfer of the retrotransposon Copia controls structural synaptic plasticity in Drosophila.
Academic Article	The Structure of a Thermostable Phage's Portal Vertex and Neck Complex Illuminates the Headful Maturation Mechanism.

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Crystallography