Item Type | Name |
Academic Article
|
Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis.
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Academic Article
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IFN-beta1a (Rebif) modifies the expression of microfilament-associated cell-cell contacts in C6 glioma cells.
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Academic Article
|
Intrinsic regulation of brain inflammatory responses.
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Academic Article
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Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients.
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Academic Article
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Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists.
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Academic Article
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The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells.
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Academic Article
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Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.
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Academic Article
|
The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.
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Academic Article
|
PPARgamma as a therapeutic target in central nervous system diseases.
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Academic Article
|
Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
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Academic Article
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Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways.
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Academic Article
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Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment.
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Academic Article
|
Inflammatory processes in Alzheimer's disease.
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Academic Article
|
Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model.
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Academic Article
|
Switching on the lights for gene therapy.
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Academic Article
|
PPARs in the brain.
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Academic Article
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The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications.
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Academic Article
|
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism.
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Academic Article
|
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
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Academic Article
|
NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits.
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Academic Article
|
Neuroglia in neurodegeneration.
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Academic Article
|
Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.
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Academic Article
|
Neuroinflammatory processes in Alzheimer's disease.
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Academic Article
|
Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
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Academic Article
|
Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice.
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Academic Article
|
Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study.
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Academic Article
|
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.
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Academic Article
|
Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation.
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Academic Article
|
Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.
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Academic Article
|
TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation.
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Academic Article
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Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice.
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Academic Article
|
Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice.
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Academic Article
|
Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment.
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Academic Article
|
Norepinephrine increases I kappa B alpha expression in astrocytes.
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Academic Article
|
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.
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Academic Article
|
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis.
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Academic Article
|
Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells.
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Academic Article
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Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors.
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Academic Article
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PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
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Academic Article
|
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
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Academic Article
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The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study.
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Academic Article
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Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression.
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Academic Article
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Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons.
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Academic Article
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Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.
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Academic Article
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Interleukin-1 beta and lipopolysaccharide decrease soluble guanylyl cyclase in brain cells: NO-independent destabilization of protein and NO-dependent decrease of mRNA.
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Academic Article
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Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
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Academic Article
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Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
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Academic Article
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Systemic inflammation induces apoptosis with variable vulnerability of different brain regions.
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Academic Article
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Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients.
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Academic Article
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Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.
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Academic Article
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Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
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Academic Article
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Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
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Academic Article
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Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms.
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Academic Article
|
Disease-modifying therapies in Alzheimer's disease: how far have we come?
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Academic Article
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GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.
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Academic Article
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Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector.
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Academic Article
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Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders.
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Academic Article
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Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome.
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Academic Article
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PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease.
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Academic Article
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PPARs in Alzheimer's Disease.
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Academic Article
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PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion.
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Academic Article
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Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients.
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Academic Article
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PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
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Academic Article
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alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation.
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Academic Article
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Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia.
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Academic Article
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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
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Academic Article
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Distinct modulation of microglial amyloid ? phagocytosis and migration by neuropeptides (i).
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Academic Article
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Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.
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Academic Article
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Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.
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Academic Article
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Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
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Academic Article
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Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis.
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Academic Article
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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.
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Academic Article
|
Glial cells in (patho)physiology.
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Academic Article
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Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.
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Academic Article
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Impact and Therapeutic Potential of PPARs in Alzheimer's Disease.
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Academic Article
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A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
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Academic Article
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Long-term neuromuscular sequelae of critical illness.
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Academic Article
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A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats.
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Academic Article
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Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
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Academic Article
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Clinical symptoms and risk factors in cerebral microangiopathy patients.
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Academic Article
|
CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.
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Academic Article
|
Studying M1 and M2 states in adult microglia.
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Concept
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Receptors, Somatostatin
|
Concept
|
Disease Models, Animal
|
Concept
|
Central Nervous System Diseases
|
Concept
|
Protein Subunits
|
Concept
|
Spain
|
Concept
|
Sequence Analysis, DNA
|
Concept
|
Central Nervous System
|
Concept
|
Extracellular Space
|
Concept
|
Mitochondrial Diseases
|
Concept
|
Synaptosomes
|
Concept
|
Survival Rate
|
Concept
|
Virus Diseases
|
Concept
|
Eye Diseases
|
Concept
|
RNA, Small Interfering
|
Concept
|
Myelin Sheath
|
Concept
|
Mass Spectrometry
|
Concept
|
Genetic Association Studies
|
Concept
|
Prostaglandin-Endoperoxide Synthases
|
Concept
|
Brain Diseases
|
Concept
|
Oxidative Stress
|
Concept
|
Communicable Diseases
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Disease Progression
|
Concept
|
Memory, Short-Term
|
Concept
|
Reactive Nitrogen Species
|
Concept
|
Amyotrophic Lateral Sclerosis
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Information Storage and Retrieval
|
Concept
|
Cell Survival
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Heat-Shock Response
|
Concept
|
HSP70 Heat-Shock Proteins
|
Concept
|
Serotonin
|
Concept
|
Multiple Sclerosis, Relapsing-Remitting
|
Concept
|
Amino Acid Substitution
|
Concept
|
Open Reading Frames
|
Concept
|
Neurodegenerative Diseases
|
Concept
|
Chronic Disease
|
Concept
|
Synaptic Transmission
|
Concept
|
Disease-Free Survival
|
Concept
|
Cohort Studies
|
Concept
|
Stroke
|
Concept
|
Acute Disease
|
Concept
|
Salmonella
|
Concept
|
Spectrum Analysis
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Nervous System Diseases
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Protein Synthesis Inhibitors
|
Concept
|
Factor Analysis, Statistical
|
Concept
|
Statistics, Nonparametric
|
Concept
|
Hand Strength
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Smell
|
Concept
|
Seizures
|
Concept
|
Complement System Proteins
|
Concept
|
Retrospective Studies
|
Concept
|
DNA Repeat Expansion
|
Concept
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Sequence Deletion
|
Concept
|
Stem Cells
|
Concept
|
Nitric Oxide Synthase
|
Concept
|
Huntington Disease
|
Concept
|
Drug Synergism
|
Concept
|
Signal Transduction
|
Concept
|
Severity of Illness Index
|
Concept
|
Spinal Cord
|
Concept
|
Superoxide Dismutase
|
Concept
|
Reactive Oxygen Species
|
Concept
|
Sepsis
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Schizophrenia
|
Concept
|
Longitudinal Studies
|
Concept
|
Solubility
|
Concept
|
Genes, Reporter
|
Concept
|
Tetrazolium Salts
|
Concept
|
STAT4 Transcription Factor
|
Concept
|
Communicable Disease Control
|
Concept
|
Synapses
|
Concept
|
Dendritic Spines
|
Concept
|
Electric Stimulation
|
Concept
|
Cell Membrane Structures
|
Concept
|
Demyelinating Diseases
|
Concept
|
Sex Factors
|
Concept
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Enzyme Stability
|
Concept
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Cellular Senescence
|
Concept
|
Proto-Oncogene Proteins pp60(c-src)
|
Concept
|
Survivors
|
Concept
|
Alzheimer Disease
|
Concept
|
Amyloid Precursor Protein Secretases
|
Concept
|
Case-Control Studies
|
Concept
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Lewy Body Disease
|
Concept
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Calcium Signaling
|
Concept
|
Prospective Studies
|
Concept
|
Neuromuscular Diseases
|
Concept
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Status Epilepticus
|
Concept
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Cross-Sectional Studies
|
Concept
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Immune System
|
Concept
|
Stress, Psychological
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Systemic Inflammatory Response Syndrome
|
Concept
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Multiple Sclerosis
|
Concept
|
Supranuclear Palsy, Progressive
|
Concept
|
Surveys and Questionnaires
|
Concept
|
Nitric Oxide Synthase Type II
|
Concept
|
Mediator Complex Subunit 1
|
Concept
|
Rats, Sprague-Dawley
|
Concept
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Limbic System
|
Concept
|
Survival
|
Concept
|
beta-Synuclein
|
Concept
|
Serine
|
Concept
|
Sulfonamides
|
Concept
|
Parkinson Disease
|
Concept
|
Somatosensory Cortex
|
Concept
|
alpha-Synuclein
|
Concept
|
Sweden
|
Concept
|
Base Sequence
|
Concept
|
Alleles
|
Concept
|
Follow-Up Studies
|
Concept
|
In Situ Nick-End Labeling
|
Concept
|
Molecular Sequence Data
|
Concept
|
Lymphocyte Subsets
|
Concept
|
CARD Signaling Adaptor Proteins
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Academic Article
|
ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease.
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Academic Article
|
Gray matter atrophy pattern in elderly with subjective memory impairment.
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Academic Article
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Long-term cerebral consequences of sepsis.
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Academic Article
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Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.
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Academic Article
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Innate immune activation in neurodegenerative disease.
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Academic Article
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Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
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Academic Article
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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
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Academic Article
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CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system.
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Academic Article
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Truncated and modified amyloid-beta species.
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Academic Article
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Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.
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Academic Article
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Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction.
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Academic Article
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Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.
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Academic Article
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Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview.
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Academic Article
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SUCLG2 identified as both a determinator of CSF A?1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
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Academic Article
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Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.
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Academic Article
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Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply.
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Academic Article
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CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.
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Academic Article
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Cortical thinning in individuals with subjective memory impairment.
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Academic Article
|
Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits.
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Academic Article
|
PLD3 in non-familial Alzheimer's disease.
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Academic Article
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Innate immunity in Alzheimer's disease.
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Academic Article
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Neuroinflammation in Alzheimer's disease.
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Academic Article
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Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease.
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Academic Article
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Effect of pioglitazone medication on the incidence of dementia.
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Academic Article
|
A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation.
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Academic Article
|
?-Secretase processing of APP inhibits neuronal activity in the hippocampus.
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Academic Article
|
Microglia in Alzheimer's disease: the good, the bad and the ugly.
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Academic Article
|
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
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Academic Article
|
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
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Academic Article
|
Thoughts on Obesity and Brain Glucose.
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Academic Article
|
Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease.
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Academic Article
|
Effect of pioglitazone treatment in a patient with secondary multiple sclerosis.
|
Academic Article
|
Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised.
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Academic Article
|
TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
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Academic Article
|
Inflammasome activation and innate immunity in Alzheimer's disease.
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Academic Article
|
Danger-associated molecular patterns in Alzheimer's disease.
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Academic Article
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IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination.
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Academic Article
|
Role of neuroinflammation in neurodegeneration: new insights.
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Academic Article
|
Personalized genetics of the cholinergic blockade of neuroinflammation.
|
Academic Article
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Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia.
|
Academic Article
|
Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
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Academic Article
|
Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
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Academic Article
|
United Again: STING and the Police.
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Academic Article
|
Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease.
|
Academic Article
|
Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease.
|
Academic Article
|
Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.
|
Academic Article
|
Screening for Niemann-Pick Type C Disease in a Memory Clinic Cohort.
|
Academic Article
|
A guiding map for inflammation.
|
Academic Article
|
Inflammasome signalling in brain function and neurodegenerative disease.
|
Academic Article
|
Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity.
|
Academic Article
|
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.
|
Academic Article
|
Microglia: You'll Never Walk Alone!
|
Academic Article
|
Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease.
|
Academic Article
|
The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease.
|
Academic Article
|
Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis.
|
Academic Article
|
Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags.
|
Academic Article
|
Innate Immunity and Neurodegeneration.
|
Academic Article
|
Targeting Neuroinflammation to Treat Alzheimer's Disease.
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Academic Article
|
Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease.
|
Academic Article
|
Neuroinflammatory responses in Alzheimer's disease.
|
Academic Article
|
Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).
|
Academic Article
|
Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial.
|
Academic Article
|
Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration.
|
Academic Article
|
Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology?
|
Academic Article
|
A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
|
Academic Article
|
Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies.
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Academic Article
|
Tau plasma levels in subjective cognitive decline: Results from the DELCODE study.
|
Academic Article
|
Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice.
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Academic Article
|
The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (A?) species on long-term potentiation (LTP).
|
Academic Article
|
Microglia in Alzheimer's disease.
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Academic Article
|
CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume.
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Academic Article
|
Microglia take centre stage in neurodegenerative disease.
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Academic Article
|
Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples.
|
Academic Article
|
Author Correction: Inflammasome signalling in brain function and neurodegenerative disease.
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Academic Article
|
Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression.
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Academic Article
|
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
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Academic Article
|
CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model.
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Academic Article
|
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.
|
Academic Article
|
Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome.
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Academic Article
|
Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study.
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Academic Article
|
Microglia in Neurodegenerative Disorders.
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Academic Article
|
In Vivo Phagocytosis Analysis of Amyloid Beta.
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Academic Article
|
[Neuroinflammation as motor of Alzheimer's disease].
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Academic Article
|
Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey.
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Academic Article
|
A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2.
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Academic Article
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Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment.
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Academic Article
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Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
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Academic Article
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Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults.
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Academic Article
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Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness.
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Academic Article
|
The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease.
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Academic Article
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Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
|
Academic Article
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Inflammasome-mediated innate immunity in Alzheimer's disease.
|
Academic Article
|
NLRP3 inflammasome activation drives tau pathology.
|
Academic Article
|
Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice.
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Academic Article
|
In vivo characterization of functional states of cortical microglia during peripheral inflammation.
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Academic Article
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Soluble A? oligomers and protofibrils induce NLRP3 inflammasome activation in microglia.
|
Academic Article
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An immune-cell signature marks the brain in Alzheimer's disease.
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Academic Article
|
Microglia in Alzheimer's disease: Local heroes!
|
Academic Article
|
Do infections have a role in the pathogenesis of Alzheimer disease?
|
Academic Article
|
Neuroimmune Connections in Aging and Neurodegenerative Diseases.
|
Academic Article
|
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
|
Academic Article
|
?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
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Academic Article
|
T cells in Alzheimer's disease: space invaders.
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Academic Article
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The Entorhinal Cortex Atrophy Score Is Diagnostic and Prognostic in Mild Cognitive Impairment.
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Academic Article
|
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
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Academic Article
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Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.
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Academic Article
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Immediate and long-term consequences of COVID-19 infections for the development of neurological disease.
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Academic Article
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Minor neuropsychological deficits in patients with subjective cognitive decline.
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Academic Article
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Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.
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Academic Article
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Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
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Academic Article
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Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study.
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Academic Article
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mTOR-dependent translation amplifies microglia priming in aging mice.
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Academic Article
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Author Correction: A guiding map for inflammation.
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Academic Article
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Time course of dementia following sepsis in German health claims data.
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Academic Article
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Major Surgery Affects Memory in Individuals with Cerebral Amyloid-? Pathology.
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Academic Article
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Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum.
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Academic Article
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Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated A? Species in a Mouse Model of Alzheimer's Disease.
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Academic Article
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Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice.
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Academic Article
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Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model.
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Academic Article
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Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age.
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Academic Article
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Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline.
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Academic Article
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In vivo mechanisms of cortical network dysfunction induced by systemic inflammation.
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Academic Article
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Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes.
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Academic Article
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Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
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Academic Article
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Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease.
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Academic Article
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Long-term exposure to fine particulate matter, lung function and cognitive performance: A prospective Dutch cohort study on the underlying routes.
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Academic Article
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Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing.
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Academic Article
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Differential interaction with TREM2 modulates microglial uptake of modified A? species.
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Academic Article
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Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies.
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Academic Article
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Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus.
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Academic Article
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Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
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Academic Article
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Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
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Academic Article
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Longitudinal Neurocognitive and Pulmonological Profile of Long COVID-19: Protocol for the COVIMMUNE-Clin Study.
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Academic Article
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Publisher Correction: Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus.
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Academic Article
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SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation.
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Academic Article
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mTOR-dependent translation amplifies microglia priming in aging mice.
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Academic Article
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A microRNA signature that correlates with cognition and is a target against cognitive decline.
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Academic Article
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TREM2 modulates differential deposition of modified and non-modified A? species in extracellular plaques and intraneuronal deposits.
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Academic Article
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Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
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Academic Article
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Cerebral dysfunctions caused by sepsis during ageing.
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Academic Article
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Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease.
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Academic Article
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Inflammasome activation in neurodegenerative diseases.
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Academic Article
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Characteristics of subjective cognitive decline associated with amyloid positivity.
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Academic Article
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Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.
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Academic Article
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Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum.
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Academic Article
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Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis.
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Academic Article
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Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease.
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Academic Article
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p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function.
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Concept
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Serine-Arginine Splicing Factors
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Concept
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Sequestosome-1 Protein
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Concept
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Soluble Guanylyl Cyclase
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Concept
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Superoxide Dismutase-1
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Concept
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Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
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Concept
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Mental Status and Dementia Tests
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Concept
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Single-Cell Analysis
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Concept
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Diagnostic Self Evaluation
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Concept
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Cerebral Small Vessel Diseases
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Concept
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Transcriptome
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Concept
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TOR Serine-Threonine Kinases
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Concept
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Sepsis-Associated Encephalopathy
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Concept
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Support Vector Machine
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Concept
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Prodromal Symptoms
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Concept
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Clustered Regularly Interspaced Short Palindromic Repeats
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Concept
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Spatial Memory
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Concept
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Spatial Learning
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Concept
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Spatial Navigation
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Academic Article
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Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
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Academic Article
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Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease.
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Academic Article
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Amyloid pathology but not APOE e4 status is permissive for tau-related hippocampal dysfunction.
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Academic Article
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New insights into the genetic etiology of Alzheimer's disease and related dementias.
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Academic Article
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Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers.
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Academic Article
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Falls at advanced age - The importance to search for benign paroxysmal positional vertigo (BPPV).
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Academic Article
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Feasibility of Digital Memory Assessments in an Unsupervised and Remote Study Setting.
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Academic Article
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Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy.
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Academic Article
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Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease.
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Academic Article
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Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease.
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Academic Article
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ApoE4 makes microglia trem2bling.
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Academic Article
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Cholinergic white matter pathways along the Alzheimer's disease continuum.
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Academic Article
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Microglia states and nomenclature: A field at its crossroads.
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Academic Article
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The Contribution of the Locus Coeruleus-Noradrenaline System Degeneration during the Progression of Alzheimer's Disease.
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Academic Article
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CNS Superficial Siderosis Mimicking a Motor Neuron Disease.
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Academic Article
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
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Academic Article
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Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.
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Academic Article
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Infection and inflammation: New perspectives on Alzheimer's disease.
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Academic Article
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Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study.
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Academic Article
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Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
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Academic Article
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NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro.
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Academic Article
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A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum.
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Academic Article
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Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2.
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Academic Article
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Exploring the ATN classification system using brain morphology.
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Academic Article
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APOE and immunity: Research highlights.
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Academic Article
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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.
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Academic Article
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Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case-Control Study Based on German Health Claims Data.
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Academic Article
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Brain Volume Changes after COVID-19 Compared to Healthy Controls by Artificial Intelligence-Based MRI Volumetry.
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Academic Article
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The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap.
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Academic Article
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Characterizing microglial senescence: Tau as a key player.
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Academic Article
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Phosphorylation-state dependent intraneuronal sorting of A? differentially impairs autophagy and the endo-lysosomal system.
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Academic Article
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[Parkinson's and Alzheimer's disease as system-wide neurodegenerative disorders].
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Academic Article
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Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression.
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Academic Article
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Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline.
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Academic Article
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Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach.
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Academic Article
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Microglia heterogeneity in health and disease.
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Academic Article
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Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline.
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Academic Article
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Inflammasomes in neurological disorders - mechanisms and therapeutic potential.
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Academic Article
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Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition.
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Academic Article
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In-depth analysis of data from the RAS-ALS study reveals new insights in rasagiline treatment for amyotrophic lateral sclerosis.
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Academic Article
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Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease.
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Academic Article
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Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients?
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Academic Article
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Immune Activation in Alzheimer Disease.
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Academic Article
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The endotoxin hypothesis of Alzheimer's disease.
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Academic Article
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Innate immune activation in neurodegenerative diseases.
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Academic Article
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TREM1 is the new kid on the block for the aging-associated innate immune response and Alzheimer's disease.
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Academic Article
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Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age-Results from the Multicentre Observational DELCODE Study.
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Academic Article
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SARS-CoV-2 infection as a cause of neurodegeneration.
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Academic Article
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Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals.
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Academic Article
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Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS.
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Academic Article
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Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease.
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Academic Article
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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
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Academic Article
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Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
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Academic Article
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A? oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
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Academic Article
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Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum.
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Academic Article
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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
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Academic Article
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Tracking neuroinflammatory biomarkers in Alzheimer's disease: a strategy for individualized therapeutic approaches?
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Academic Article
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Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer's Disease Dementia using ELSI-Net.
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Academic Article
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Inflammatory aspects of Alzheimer's disease.
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Academic Article
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Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.
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Academic Article
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The putative contribution of cellular senescence to driving tauopathies.
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Academic Article
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Tunneling Nanotubes in the Brain.
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Academic Article
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The impact of neuroinflammation on neuronal integrity.
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Academic Article
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Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study.
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Academic Article
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Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation.
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Academic Article
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Passive anti-amyloid ? immunotherapy in Alzheimer's disease-opportunities and challenges.
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Academic Article
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Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy.
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Academic Article
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Identification of isoAsp7-A? as a major A? variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia.
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