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Gierasch, Lila
One or more keywords matched the following items that are connected to
Gierasch, Lila
Item Type
Name
Academic Article
The crystal structure of the GroES co-chaperonin at 2.8 A resolution.
Academic Article
Signal sequences: the same yet different.
Academic Article
Orientations of helical peptides in membrane bilayers by solid state NMR spectroscopy.
Academic Article
Local interactions in a Schellman motif dictate interhelical arrangement in a protein fragment.
Academic Article
Different conformations for the same polypeptide bound to chaperones DnaK and GroEL.
Academic Article
Combined use of molecular dynamics simulations and NMR to explore peptide bond isomerization and multiple intramolecular hydrogen-bonding possibilities in a cyclic pentapeptide, cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article
Constrained peptides: models of bioactive peptides and protein substructures.
Academic Article
Basis of substrate binding by the chaperonin GroEL.
Academic Article
Mutating the charged residues in the binding pocket of cellular retinoic acid-binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability.
Academic Article
The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle.
Academic Article
Domain interactions in E. coli SRP: stabilization of M domain by RNA is required for effective signal sequence modulation of NG domain.
Academic Article
Solution conformations of two flexible cyclic pentapeptides: cyclo(Gly-Pro-D-Phe-Gly-Ala) and cyclo(Gly-Pro-D-Phe-Gly-Val).
Academic Article
Impact of a micellar environment on the conformations of two cyclic pentapeptides.
Academic Article
Role of local sequence in the folding of cellular retinoic abinding protein I: structural propensities of reverse turns.
Academic Article
Sequence and structural analysis of cellular retinoic acid-binding proteins reveals a network of conserved hydrophobic interactions.
Academic Article
Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase.
Academic Article
Evolutionary coupling of structural and functional sequence information in the intracellular lipid-binding protein family.
Academic Article
Structural insights into substrate binding by the molecular chaperone DnaK.
Academic Article
Design of biologically active, conformationally constrained GnRH antagonists.
Academic Article
Functional signal peptides bind a soluble N-terminal fragment of SecA and inhibit its ATPase activity.
Academic Article
Biophysical studies of signal peptides: implications for signal sequence functions and the involvement of lipid in protein export.
Academic Article
Use of synthetic signal sequences to explore the protein export machinery.
Academic Article
A tribute to the career of a gentle giant of peptide science.
Academic Article
Cyclic pentapeptides as models for reverse turns: determination of the equilibrium distribution between type I and type II conformations of Pro-Asn and Pro-Ala beta-turns.
Academic Article
Comparison of helix stability in wild-type and mutant LamB signal sequences.
Academic Article
Exploring the interactions between signal sequences and E. coli SRP by two distinct and complementary crosslinking methods.
Academic Article
Sending signals dynamically.
Academic Article
T-cell antigenic peptides from sperm whale myoglobin fold as amphipathic helices: a possible determinant for immunodominance?
Academic Article
The chaperonin GroEL binds a polypeptide in an alpha-helical conformation.
Academic Article
Signal sequences.
Academic Article
A career pathway in protein folding: from model peptides to postreductionist protein science.
Academic Article
Native structural propensity in cellular retinoic acid-binding protein I 64-88: the role of locally encoded structure in the folding of a beta-barrel protein.
Academic Article
The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation.
Academic Article
Interaction of peptides corresponding to mitochondrial presequences with membranes.
Academic Article
Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.
Academic Article
1H and 15N resonance assignments and secondary structure of cellular retinoic acid-binding protein with and without bound ligand.
Academic Article
Effect of charged residue substitutions on the membrane-interactive properties of signal sequences of the Escherichia coli LamB protein.
Academic Article
Effect of charged residue substitutions on the thermodynamics of signal peptide-lipid interactions for the Escherichia coli LamB signal sequence.
Academic Article
Reorganization of lipid domain structure in membranes by a transmembrane peptide: an ESR spin label study on the effect of the Escherichia coli outer membrane protein A signal peptide on the fluid lipid domain connectivity in binary mixtures of dimyristoyl phosphatidylcholine and distearoyl phosphatidylcholine.
Academic Article
GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation.
Academic Article
Membrane-bound conformation of a signal peptide: a transferred nuclear Overhauser effect analysis.
Academic Article
Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments.
Academic Article
Side chain-backbone hydrogen bonding contributes to helix stability in peptides derived from an alpha-helical region of carboxypeptidase A.
Academic Article
Hydrophobic content and lipid interactions of wild-type and mutant OmpA signal peptides correlate with their in vivo function.
Academic Article
The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA.
Academic Article
Finding the fittest fold: using the evolutionary record to design new proteins.
Academic Article
Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Academic Article
Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region.
Academic Article
Synthesis and crystal structures of Boc-L-Asn-L-Pro-OBzl.CH3OH and dehydration side product, Boc-beta-cyano-L-alanine-L-Pro-OBzl.
Academic Article
Editorial: Passing of a gentle giant of peptide science: in memoriam, R. Bruce Merrifield.
Academic Article
Reduced tendency to form a beta turn in peptides from the P22 tailspike protein correlates with a temperature-sensitive folding defect.
Academic Article
Post-reductionist protein science, or putting Humpty Dumpty back together again.
Academic Article
Helix formation and stability in a signal sequence.
Academic Article
Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Academic Article
An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.
Academic Article
Conformations of signal peptides induced by lipids suggest initial steps in protein export.
Academic Article
The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of ?-Sheets.
Academic Article
In vivo function and membrane binding properties are correlated for Escherichia coli lamB signal peptides.
Academic Article
Characterization of a functionally important mobile domain of GroES.
Academic Article
Conformational analysis of a highly potent dicyclic gonadotropin-releasing hormone antagonist by nuclear magnetic resonance and molecular dynamics.
Academic Article
Conformation of a heptapeptide substrate bound to protein farnesyltransferase.
Academic Article
The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Concept
Data Interpretation, Statistical
Concept
Science
Concept
Biological Science Disciplines
Concept
Databases, Protein
Concept
Molecular Sequence Data
Academic Article
Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge.
Academic Article
What's in a Name?
Academic Article
For the Sake of Science.
Academic Article
For the sake of science.
Academic Article
For the sake of science.
Academic Article
Celebrating science's next generation.
Academic Article
Faster publication advances your science: The three R's.
Academic Article
The data must be accessible to all.
Academic Article
The data must be accessible to all.
Academic Article
The Data Must Be Accessible to All.
Academic Article
How the Protein Data Bank changed biology: An introduction to the JBC Reviews thematic series, part 1.
Academic Article
How the Protein Data Bank changed biology: An introduction to the JBC Reviews thematic series, part 2.
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Data
Science