| Item Type | Name |
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Academic Article
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Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.
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Academic Article
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Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses.
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Academic Article
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Immunization with a replication-deficient mutant of herpes simplex virus type 1 (HSV-1) induces a CD8+ cytotoxic T-lymphocyte response and confers a level of protection comparable to that of wild-type HSV-1.
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Academic Article
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The impact of psychological stress on the efficacy of anti-viral adoptive immunotherapy in an immunocompromised host.
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Academic Article
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T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.
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Academic Article
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Dynamics of memory T cell proliferation under conditions of heterologous immunity and bystander stimulation.
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Academic Article
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A molecular basis for how a single TCR interfaces multiple ligands.
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Academic Article
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Immunization with a single major histocompatibility complex class I-restricted cytotoxic T-lymphocyte recognition epitope of herpes simplex virus type 2 confers protective immunity.
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Academic Article
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Heterologous immunity and the CD8 T cell network.
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Academic Article
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Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections.
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Academic Article
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Virus-specific CD8 T cells in peripheral tissues are more resistant to apoptosis than those in lymphoid organs.
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Academic Article
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Immunogenicity of herpes simplex virus type 1 mutants containing deletions in one or more alpha-genes: ICP4, ICP27, ICP22, and ICP0.
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Academic Article
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CD8 T cell responses to viral infections in sequence.
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Academic Article
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CD8 memory T cells: cross-reactivity and heterologous immunity.
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Academic Article
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Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.
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Academic Article
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Consequences of cross-reactive and bystander CTL responses during viral infections.
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Academic Article
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Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression.
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Academic Article
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Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice.
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Academic Article
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Frontiers in nephrology: heterologous immunity, T cell cross-reactivity, and alloreactivity.
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Academic Article
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Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance.
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Academic Article
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Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
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Academic Article
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TLR agonists abrogate co-stimulation blockade-induced mixed chimerism and transplantation tolerance.
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Academic Article
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Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
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Academic Article
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Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung.
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Academic Article
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Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function.
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Academic Article
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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.
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Academic Article
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Humanized mouse models to study human diseases.
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Academic Article
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Heterologous immunity between viruses.
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Academic Article
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Human allograft rejection in humanized mice: a historical perspective.
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Academic Article
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Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice.
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Academic Article
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Humanized mice for immune system investigation: progress, promise and challenges.
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Academic Article
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Preapoptotic phenotype of viral epitope-specific CD8 T cells precludes memory development and is an intrinsic property of the epitope.
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Academic Article
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Rapid conversion of effector mechanisms from NK to T cells during virus-induced lysis of allogeneic implants in vivo.
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Academic Article
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Rapid production of TNF-alpha following TCR engagement of naive CD8 T cells.
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Academic Article
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TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts.
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Academic Article
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Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.
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Academic Article
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Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.
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Academic Article
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Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity.
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Academic Article
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Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
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Academic Article
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Protection against vaccinia virus challenge by CD8 memory T cells resolved by molecular mimicry.
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Academic Article
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TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.
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Academic Article
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CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections.
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Academic Article
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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
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Academic Article
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Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice.
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Academic Article
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Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.
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Academic Article
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Humanized mice as a preclinical tool for infectious disease and biomedical research.
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Academic Article
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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Academic Article
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Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death.
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Academic Article
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Humanized mice for the study of infectious diseases.
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Concept
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Immunotherapy
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Concept
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Enzyme-Linked Immunosorbent Assay
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Concept
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Cytotoxicity Tests, Immunologic
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Concept
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Immunity, Cellular
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Concept
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Graft Enhancement, Immunologic
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Concept
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Immune System Diseases
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Concept
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Immunity
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Concept
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Chromatin Immunoprecipitation
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Concept
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Transplantation Immunology
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Concept
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Models, Immunological
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Concept
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Immunophenotyping
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Concept
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Immunosuppressive Agents
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Concept
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Immunity, Mucosal
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Concept
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Organoids
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Concept
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Immunocompromised Host
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Concept
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Acquired Immunodeficiency Syndrome
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Concept
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Immunity, Innate
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Concept
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Immunoglobulin M
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Concept
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Immunity, Humoral
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Concept
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Immunoglobulin G
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Concept
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Immunodominant Epitopes
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Concept
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Severe Combined Immunodeficiency
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Concept
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Cytotoxicity, Immunologic
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Concept
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Immunization, Passive
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Concept
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Immunoglobulin E
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Concept
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Immunotherapy, Adoptive
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Concept
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Adaptive Immunity
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Concept
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Immune System
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Concept
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Receptors, Immunologic
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Concept
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Immunization
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Concept
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Immunohistochemistry
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Concept
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Immune Tolerance
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Concept
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Immunologic Memory
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Academic Article
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Overcoming current limitations in humanized mouse research.
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Academic Article
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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
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Academic Article
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
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Academic Article
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Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection.
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Academic Article
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Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development.
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Academic Article
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Generation of improved humanized mouse models for human infectious diseases.
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Academic Article
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MHC basis of T cell-dependent heterologous immunity to arenaviruses.
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Academic Article
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Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice.
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Academic Article
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Extensive double humanization of both liver and hematopoiesis in FRGN mice.
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Academic Article
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
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Academic Article
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Humanized Mouse Models for Transplant Immunology.
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Academic Article
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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.
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Academic Article
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Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease.
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Academic Article
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Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.
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Academic Article
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Humanized Mouse Models of Clinical Disease.
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Academic Article
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Improved B cell development in humanized NOD-scid IL2R?null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.
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Academic Article
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A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo.
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Academic Article
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Gene Therapy with an Adeno-Associated Viral Vector Expressing Human Interleukin-2 Alters Immune System Homeostasis in Humanized Mice.
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Academic Article
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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
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Academic Article
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Human immune system development and survival of non-obese diabetic (NOD)-scid IL2r?(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.
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Academic Article
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Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
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Academic Article
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Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
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Academic Article
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Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim.
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Academic Article
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Humanized mouse models of immunological diseases and precision medicine.
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Academic Article
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Creation of PDX-Bearing Humanized Mice to Study Immuno-oncology.
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Academic Article
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Humanized immune system mouse models: progress, challenges and opportunities.
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Academic Article
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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
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Academic Article
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Modeling Type 1 Diabetes In?Vitro Using Human Pluripotent Stem Cells.
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Academic Article
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Modeling human T1D-associated autoimmune processes.
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Concept
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Immunity, Heterologous
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Concept
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Sialic Acid Binding Immunoglobulin-like Lectins
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Academic Article
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Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells.
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Academic Article
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Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
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Academic Article
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Humanized mouse models for immuno-oncology research.
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Academic Article
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I-Ag7 ?56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes.
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Academic Article
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NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.
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Academic Article
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Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.
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Academic Article
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Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis.
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Academic Article
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Generation of the NeoThy mouse model for human immune system studies.
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Academic Article
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Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response.
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Academic Article
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Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism.
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Academic Article
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A human immune/muscle xenograft model of FSHD muscle pathology.
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Academic Article
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IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas.
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Academic Article
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IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas.
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Academic Article
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Transplantation of human kidney organoids elicited a robust allogeneic response in a humanized mouse model.
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Academic Article
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Partial remission of type 1 diabetes: Do immunometabolic events define the honeymoon period?
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