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Brodsky, Michael

One or more keywords matched the following properties of Brodsky, Michael

Property	Value
Rotation Projects	Potential Rotation Projects We are utilizing a variety of technologies to study p53 regulation and function in Drosophila. These include genetic screens, molecular biology, fluorescence and scanning electron microscopy, tissue culture, RNAi, homologous recombination, and others. Rotation projects in this lab will be determined based on a combination of the student's and PI's interests. Possible projects are listed below: Project 1: A genetic screen for new regulators of Drosophila p53. Project 2: Using RNAi and homologous recombination to study regulators of p53. Project 3: Characterization of p53 activation in Drosophila tissue culture cells by flurescence microscopy, Real-Time PCR, and RNAi. Project 4: Genetic analysis of Drosophila p53 targets identified in microarray experiments.

Property

Value

Rotation Projects

Potential Rotation Projects

We are utilizing a variety of technologies to study p53 regulation and function in Drosophila. These include genetic screens, molecular biology, fluorescence and scanning electron microscopy, tissue culture, RNAi, homologous recombination, and others. Rotation projects in this lab will be determined based on a combination of the student's and PI's interests. Possible projects are listed below:

Project 1: A genetic screen for new regulators of Drosophila p53.

Project 2: Using RNAi and homologous recombination to study regulators of p53.

Project 3: Characterization of p53 activation in Drosophila tissue culture cells by flurescence microscopy, Real-Time PCR, and RNAi.

Project 4: Genetic analysis of Drosophila p53 targets identified in microarray experiments.

One or more keywords matched the following items that are connected to Brodsky, Michael

Item Type	Name
Academic Article	CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems.
Academic Article	DNA-binding-domain fusions enhance the targeting range and precision of Cas9.
Academic Article	Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion.
Academic Article	A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats.
Academic Article	Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.
Concept	Clustered Regularly Interspaced Short Palindromic Repeats
Concept	CRISPR-Cas Systems
Concept	CRISPR-Associated Proteins
Academic Article	CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro.

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CRISPR
screens