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Dekker, Job

One or more keywords matched the following items that are connected to Dekker, Job

Item Type	Name
Academic Article	Two regions within the DNA binding domain of nuclear factor I interact with DNA and stimulate adenovirus DNA replication independently.
Academic Article	A closer look at long-range chromosomal interactions.
Academic Article	The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications.
Academic Article	Gene regulation in the third dimension.
Academic Article	Disease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening.
Academic Article	Integrating one-dimensional and three-dimensional maps of genomes.
Academic Article	Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.
Academic Article	Enhanced yeast one-hybrid assays for high-throughput gene-centered regulatory network mapping.
Academic Article	Genome architecture and expression.
Academic Article	CTCF and cohesin help neurons raise their self-awareness.
Academic Article	An encyclopedia of mouse DNA elements (Mouse ENCODE).
Academic Article	An integrated encyclopedia of DNA elements in the human genome.
Academic Article	The long-range interaction landscape of gene promoters.
Academic Article	From cells to chromatin: capturing snapshots of genome organization with 5C technology.
Academic Article	3C-based technologies to study the shape of the genome.
Academic Article	Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.
Academic Article	A mechanical basis for chromosome function.
Academic Article	Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.
Academic Article	Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements.
Academic Article	Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Academic Article	A mechanism for Ikaros regulation of human globin gene switching.
Academic Article	Long-range chromosomal interactions and gene regulation.
Academic Article	Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C).
Academic Article	Determining spatial chromatin organization of large genomic regions using 5C technology.
Academic Article	Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Academic Article	Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene.
Academic Article	Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Academic Article	The three-dimensional folding of the a-globin gene domain reveals formation of chromatin globules.
Academic Article	A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.
Academic Article	Chromatin globules: a common motif of higher order chromosome structure?
Academic Article	A user's guide to the encyclopedia of DNA elements (ENCODE).
Academic Article	The structure and function of chromatin and chromosomes.
Academic Article	Evidence for transcript networks composed of chimeric RNAs in human cells.
Academic Article	Hi-C: a comprehensive technique to capture the conformation of genomes.
Academic Article	Analysis of long-range chromatin interactions using Chromosome Conformation Capture.
Academic Article	HiTC: exploration of high-throughput 'C' experiments.
Academic Article	Iterative correction of Hi-C data reveals hallmarks of chromosome organization.
Academic Article	The accessible chromatin landscape of the human genome.
Academic Article	Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome.
Academic Article	The hierarchy of the 3D genome.
Academic Article	Nuclear biology: what's been most surprising?
Academic Article	Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods?
Academic Article	Organization of the mitotic chromosome.
Concept	Human Genome Project
Concept	Humans
Concept	Chromosomes, Human, Pair 16
Concept	Adenoviruses, Human
Concept	Chromosomes, Human
Concept	Mammary Glands, Human
Concept	Chromosomes, Human, Pair 14
Concept	Chromosomes, Human, Pair 1
Concept	Genome, Human
Concept	Chromosomes, Human, Pair 21
Academic Article	Defining functional DNA elements in the human genome.
Academic Article	The Hitchhiker's guide to Hi-C analysis: practical guidelines.
Academic Article	Genomics tools for unraveling chromosome architecture.
Academic Article	Genome-wide maps of nuclear lamina interactions in single human cells.
Academic Article	Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells.
Academic Article	Long-Range Chromatin Interactions.
Academic Article	Structural and functional diversity of Topologically Associating Domains.
Academic Article	HiC-Pro: an optimized and flexible pipeline for Hi-C data processing.
Academic Article	Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus.
Academic Article	Activation of proto-oncogenes by disruption of chromosome neighborhoods.
Academic Article	The 3D Genome as Moderator of Chromosomal Communication.
Academic Article	TAD disruption as oncogenic driver.
Academic Article	SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.
Academic Article	RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.
Academic Article	Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma.
Academic Article	Mapping the 3D genome: Aiming for consilience.
Academic Article	Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation.
Academic Article	Epigenetic characteristics of the mitotic chromosome in 1D and 3D.
Academic Article	Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation.
Academic Article	C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2.
Academic Article	CBF?-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
Academic Article	Polymerase Chain Reaction (PCR) Detection of 3C Ligation Products Present in 3C, ChIP-Loop, and Control Libraries: Library Titration and Interaction Frequency Analysis.
Academic Article	Integrative detection and analysis of structural variation in cancer genomes.
Academic Article	Formaldehyde Cross-Linking.
Academic Article	Higher-Order Organization Principles of Pre-translational mRNPs.
Academic Article	ChIP-chip.
Academic Article	Preparation of Cross-Linked Chromatin for ChIP.
Academic Article	ChIP.
Academic Article	Generation of Control Ligation Product Libraries for 3C Analyses.
Academic Article	The 4D nucleome project.
Academic Article	CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning.
Academic Article	Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization.
Academic Article	Measuring the reproducibility and quality of Hi-C data.
Academic Article	Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment.
Academic Article	Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.
Academic Article	A chromosome folding intermediate at the condensin-to-cohesin transition during telophase.
Academic Article	Ultrastructural Details of Mammalian Chromosome Architecture.
Academic Article	Large domains of heterochromatin direct the formation of short mitotic chromosome loops.
Academic Article	Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain.
Academic Article	Multi-contact 3C reveals that the human genome during interphase is largely not entangled.
Academic Article	Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML.
Academic Article	Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics.
Academic Article	Systematic evaluation of chromosome conformation capture assays.
Concept	Human Embryonic Stem Cells
Academic Article	Expanded encyclopaedias of DNA elements in the human and mouse genomes.
Academic Article	Cohesin-mediated loop anchors confine the locations of human replication origins.
Academic Article	Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization.
Academic Article	Mechanisms of insertions at a DNA double-strand break.
Academic Article	Enhancer-driven 3D chromatin domain folding modulates transcription in human mammary tumor cells.
Academic Article	Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Academic Article	Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations.
Academic Article	An integrated view of the structure and function of the human 4D nucleome.
Academic Article	The chromosome folding problem and how cells solve it.
Academic Article	Rules of engagement for condensins and cohesins guide mitotic chromosome formation.
Academic Article	TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells.

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