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Search Results to Jason Matthew Shohet MD, PhD

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One or more keywords matched the following properties of Shohet, Jason

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keywords p53 Tumor Suppressor Protein

One or more keywords matched the following items that are connected to Shohet, Jason

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Concept Tumor Suppressor Protein p53
Academic Article WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
Academic Article G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.
Academic Article WIP1 phosphatase as a potential therapeutic target in neuroblastoma.
Academic Article MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells.
Academic Article The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.
Academic Article MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death.
Academic Article Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo.
Academic Article Targeted molecular therapy for neuroblastoma: the ARF/MDM2/p53 axis.
Academic Article Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma.
Academic Article Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma.
Academic Article Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma.
Academic Article MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance.
Academic Article A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma.

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