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keywords
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primate evolution
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Rotation Projects
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1- Determinants of human neuronal transcriptional specification 2- Neuronal activity-dependent transcription of the primate brain 3- OSTN function in developing human cortical neurons
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Summary
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The development and maturation of the brain is dependent on neuronal activity. The human brain continues to mature over 20-30 years, meaning sensory input continuously shapes neural circuit architecture over decades. Using human stem cells, rodent, and non-human primate tissue, the Boulting Laboratory investigates human neuronal activity-dependent gene dynamics evolved in the primate brain.
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