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Martinez, Fernando

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Item Type	Name
Concept	Needs Assessment
Concept	Self-Assessment
Concept	Treatment Outcome
Concept	Clinical Trials, Phase III as Topic
Concept	Clinical Trials, Phase II as Topic
Concept	Hydroxymethylglutaryl-CoA Reductase Inhibitors
Concept	Clinical Protocols
Concept	Clinical Trials as Topic
Concept	Risk Assessment
Concept	Clinical Decision-Making
Concept	Patient Reported Outcome Measures
Concept	Adaptive Clinical Trials as Topic
Concept	Clinical Deterioration
Concept	Symptom Assessment
Concept	Patient Outcome Assessment
Academic Article	Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation.
Academic Article	Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS.
Academic Article	Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy.
Academic Article	Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis.
Academic Article	Design of Idiopathic Pulmonary Fibrosis Clinical Trials in the Era of Approved Therapies.
Academic Article	Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease.
Academic Article	InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations.
Academic Article	Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.
Academic Article	Comparison of Pirfenidone and Nintedanib: Post Hoc Analysis of the CleanUP-IPF Study.
Academic Article	Analysis of culture-dependent versus culture-independent techniques for identification of bacteria in clinically obtained bronchoalveolar lavage fluid.
Academic Article	The value of early diagnosis for effective management of chronic obstructive pulmonary disease.
Academic Article	A simplified score to quantify comorbidity in COPD.
Academic Article	A single blood eosinophil count measurement is as good as two for prediction of ICS treatment response in the IMPACT trial.
Academic Article	Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial.
Academic Article	Diagnostic Likelihood Thresholds That Define a Working Diagnosis of Idiopathic Pulmonary Fibrosis.
Academic Article	The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study.
Academic Article	Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori.
Academic Article	Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study.
Academic Article	Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials.
Academic Article	Preacinar Arterial Dilation Mediates Outcomes of Quantitative Interstitial Abnormalities in the COPDGene Study.
Academic Article	Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre-Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward.
Academic Article	Development and initial validation of a self-scored COPD Population Screener Questionnaire (COPD-PS).
Academic Article	Clinical and Genetic Associations of Objectively Identified Interstitial Changes in?Smokers.
Academic Article	Clinical significance of radiologic characterizations in COPD.
Academic Article	Screening for Chronic Obstructive Pulmonary Disease: Unmet Needs and Future Considerations.
Academic Article	Physiological and computed tomographic predictors of outcome from lung volume reduction surgery.
Academic Article	Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis.
Academic Article	Phase 2B Study of Inhaled RVT-1601 for Chronic Cough in Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized, Placebo-controlled Study (SCENIC Trial).
Academic Article	Pitfalls in developing new compounds for idiopathic pulmonary fibrosis.
Academic Article	Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.
Academic Article	Association of hospital admission and forced vital capacity endpoints with survival in patients with idiopathic pulmonary fibrosis: analysis of a pooled cohort from three clinical trials.
Academic Article	Efficacy and Safety of Admilparant, an LPA1 Antagonist, in Pulmonary Fibrosis: A Phase 2 Randomized Clinical Trial.
Academic Article	Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR.
Academic Article	ECG-based risk factors for adverse cardiopulmonary events and treatment outcomes in COPD.
Academic Article	Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004.
Academic Article	Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study.
Academic Article	International Differences in the Frequency of Chronic Obstructive Pulmonary Disease Exacerbations Reported in Three Clinical Trials.
Academic Article	Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease.
Academic Article	Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease.
Academic Article	Idiopathic Pulmonary Fibrosis: The Association between the Adaptive Multiple Features Method and Fibrosis Outcomes.
Academic Article	A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography.
Academic Article	Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).
Academic Article	Any Decrease in Lung Function is Associated With Worse Clinical Outcomes: Post Hoc Analysis of the IMPACT Interventional Trial.
Academic Article	Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency.
Academic Article	Impact of the COVID-19 Pandemic on Outcomes of CAPTURE: A Primary Care Chronic Obstructive Pulmonary Disease Screening Clinical Trial.
Academic Article	Treatment of Persistent Cough in Subjects with Idiopathic Pulmonary Fibrosis (IPF) with Gefapixant, a P2X3 Antagonist, in a Randomized, Placebo-Controlled Clinical Trial.
Academic Article	Serum biomarkers and outcomes in patients with moderate COPD: a substudy of the randomised SUMMIT trial.
Academic Article	Patient-centered Outcomes Research in Interstitial Lung Disease: An Official American Thoracic Society Research Statement.
Academic Article	Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial.
Academic Article	Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in Chronic Obstructive Pulmonary Disease.
Academic Article	Assessment of patients with chronic obstructive pulmonary disease.
Academic Article	Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort.
Academic Article	Integrating health status and survival data: the palliative effect of lung volume reduction surgery.
Academic Article	Outcomes for COPD pharmacological trials: from lung function to biomarkers.
Academic Article	Nintedanib and Sildenafil in Patients with Idiopathic Pulmonary Fibrosis and Right Heart Dysfunction. A Prespecified Subgroup Analysis of a Double-Blind Randomized Clinical Trial (INSTAGE).
Academic Article	Design and rationale for the prospective treatment efficacy in IPF using genotype for NAC selection (PRECISIONS) clinical trial.
Academic Article	Acute exacerbation of chronic bronchitis: expanding short-course therapy.
Academic Article	Short-term and long-term outcomes after bilateral lung volume reduction surgery : prediction by quantitative CT.
Academic Article	Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.
Academic Article	Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes.
Academic Article	MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis--validation of two novel biomarker assays.
Academic Article	Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS).
Academic Article	Protocol Summary of the COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE) Validation in Primary Care Study.
Academic Article	Precision medicine in COPD: where are we and where do we need to go?
Academic Article	Clinical Approach to the Therapy of Asthma-COPD Overlap.
Academic Article	Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.
Academic Article	Relationship between pathologic characteristics of peripheral airways and outcome after lung volume reduction surgery in severe chronic obstructive pulmonary disease.
Academic Article	Development of the chronic obstructive pulmonary disease morning symptom diary (COPD-MSD).
Academic Article	Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment.
Academic Article	An Update on Outcomes for COPD Pharmacological Trials: A COPD Investigators Report - Reassessment of the 2008 American Thoracic Society/European Respiratory Society Statement on Outcomes for COPD Pharmacological Trials.
Academic Article	Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease.
Academic Article	Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting ?2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial.
Academic Article	Chronic Respiratory Symptoms with Normal Spirometry. A Reliable Clinical Entity?
Academic Article	Establishing content-validity of a disease-specific health-related quality of life instrument for patients with chronic hypersensitivity pneumonitis.
Academic Article	Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort.
Academic Article	Ratio of FEV1/Slow Vital Capacity of?< 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function.
Academic Article	Baseline values and short serial change: a "road map" for a poor early outcome in idiopathic pulmonary fibrosis.
Academic Article	Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.
Academic Article	Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort.
Academic Article	Simvastatin for the prevention of exacerbations in moderate-to-severe COPD.
Academic Article	Azithromycin for prevention of exacerbations of COPD.
Academic Article	Closing the Evidence Gap in Interstitial Lung Disease. The Promise of Real-World Data.
Academic Article	Icenticaftor, a CFTR Potentiator, in COPD: A Multicenter, Parallel-Group, Double-Blind Clinical Trial.
Academic Article	An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline.
Academic Article	The effect of exacerbation history on outcomes in the IMPACT trial.
Academic Article	Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.
Academic Article	Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts.
Academic Article	Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials.
Academic Article	Optimizing the 6-min walk test as a measure of exercise capacity in COPD.
Academic Article	Effect of chronic mucus hypersecretion on treatment responses to inhaled therapies in patients with chronic obstructive pulmonary disease: Post hoc analysis of the IMPACT trial.
Academic Article	Patient-reported Outcomes for the Detection, Quantification, and Evaluation of Chronic Obstructive Pulmonary Disease Exacerbations.
Academic Article	Monotherapy versus dual therapy for community-acquired pneumonia in hospitalized patients.
Academic Article	Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
Academic Article	Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.
Academic Article	Reply: idiopathic pulmonary fibrosis: perspectives on clinically meaningful primary endpoints in phase 3 clinical trials.
Academic Article	Determinants of Response to Roflumilast in Severe Chronic Obstructive Pulmonary Disease. Pooled Analysis of Two Randomized Trials.
Academic Article	The clinical impact of non-obstructive chronic bronchitis in current and former smokers.
Academic Article	Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization.
Academic Article	Update in diffuse parenchymal lung diseases 2005.
Academic Article	NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort.
Academic Article	Risk of Exacerbation and Pneumonia with Single-Inhaler Triple versus Dual Therapy in IMPACT.
Academic Article	Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease.
Academic Article	Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort.
Academic Article	An American Thoracic Society Official Research Statement: Future Directions in Lung Fibrosis Research.
Academic Article	Confronting the Challenge of COPD: What Is New in the Approaches to Diagnosis, Treatment, and Patient Outcomes.
Academic Article	Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.
Academic Article	Prognostic value of clinically important deterioration in COPD: IMPACT trial analysis.
Academic Article	Effects of baseline symptom burden on treatment response in COPD.
Academic Article	The influence of social support on COPD outcomes mediated by depression.
Academic Article	Surgical therapy for chronic obstructive pulmonary disease.
Academic Article	Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS).
Academic Article	Effect of beta-blockers on exacerbation rate and lung function in chronic obstructive pulmonary disease (COPD).
Academic Article	TOLLIP SNP and Antimicrobial Treatment Effect in Idiopathic Pulmonary Fibrosis.
Academic Article	Community-acquired pneumonia.
Academic Article	The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions.
Academic Article	Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.
Academic Article	CT metrics of airway disease and emphysema in severe COPD.
Academic Article	Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis-Interstitial Lung Disease: Open-Label Extension of a Phase 3 Randomized Controlled Trial.
Academic Article	Fluticasone Furoate, Vilanterol, and Lung Function Decline in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk.
Academic Article	Prevalence and clinical correlates of bronchoreversibility in severe emphysema.
Academic Article	Higher COPD Assessment Test Score Associated With Greater Exacerbations Risk: A Post Hoc Analysis of the IMPACT Trial.
Academic Article	Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers.
Academic Article	Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey.
Academic Article	Gender influences Health-Related Quality of Life in IPF.
Academic Article	Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.
Academic Article	POINT: Can Screening for COPD Improve Outcomes? Yes.
Academic Article	Effect of Triple Therapy on Cardiovascular and Severe Cardiopulmonary Events in Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of a Randomized, Double-Blind, Phase 3 Clinical Trial (ETHOS).
Academic Article	Gender differences in symptoms and care delivery for chronic obstructive pulmonary disease.
Academic Article	Pulse Wave Velocity in Chronic Obstructive Pulmonary Disease and the Impact of Inhaled Therapy (SUMMIT): A Randomized Double-Blind Clinical Trial.
Academic Article	Weight gain after lung volume reduction surgery is not correlated with improvement in pulmonary mechanics.
Academic Article	Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease.
Academic Article	Clinical implications of macrolide therapy in chronic sinopulmonary diseases.
Academic Article	A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis.
Academic Article	Integrating Clinical Probability into the Diagnostic Approach to Idiopathic Pulmonary Fibrosis: An International Working Group Perspective.
Academic Article	Assessment of Home-based Monitoring in Adults with Chronic Lung Disease: An Official American Thoracic Society Research Statement.
Academic Article	An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.
Academic Article	Randomised clinical trial to determine the safety of quercetin supplementation in patients with chronic obstructive pulmonary disease.
Academic Article	Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.
Academic Article	Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study.
Academic Article	Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.
Academic Article	Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial.
Academic Article	A Phase IIb Randomized Clinical Study of an Anti-av?6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis.
Academic Article	Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene.
Academic Article	Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis.
Academic Article	Long-Acting ?-Agonist/Inhaled Corticosteroid in Patients with Chronic Obstructive Pulmonary Disease with Cardiovascular Disease or Risk: A Factorial Analysis of the SUMMIT Clinical Trial.
Academic Article	Clinical relevance of macrolide-resistant Streptococcus pneumoniae for community-acquired pneumonia.
Academic Article	Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
Academic Article	Surgical patient outcomes after the increased use of bilateral lung transplantation.
Academic Article	Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial.
Academic Article	The Effect of Inhaled Corticosteroid Withdrawal and Baseline Inhaled Treatment on Exacerbations in the IMPACT Study. A Randomized, Double-Blind, Multicenter Clinical Trial.
Academic Article	CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab.
Academic Article	Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial.
Academic Article	Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease.
Academic Article	Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved?Spirometry in SPIROMICS.
Academic Article	Effect of daily azithromycin therapy and adherence on readmission risk in COPD.
Academic Article	Longitudinal Outcomes in Pi*MZ Alpha-1 Antitrypsin Deficient Individuals with Tobacco Smoking History from the SPIROMICS Cohort.
Academic Article	Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype.
Academic Article	Deep Learning Estimation of Small Airways Disease from Inspiratory Chest CT: Clinical Validation, Repeatability, and Associations with Adverse Clinical Outcomes in COPD.

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