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Kotin, Robert

One or more keywords matched the following items that are connected to Kotin, Robert

Item Type	Name
Academic Article	Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6.
Concept	Dependovirus
Academic Article	Process optimization of large-scale production of recombinant adeno-associated vectors using dielectric spectroscopy.
Academic Article	The Rep52 gene product of adeno-associated virus is a DNA helicase with 3'-to-5' polarity.
Academic Article	Recombinant adeno-associated virus for the generation of autologous, gene-modified tumor vaccines: evidence for a high transduction efficiency into primary epithelial cancer cells.
Academic Article	Real-time imaging of convection-enhanced delivery of viruses and virus-sized particles.
Academic Article	MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy.
Academic Article	Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2.
Academic Article	Adenoassociated virus-mediated transfer of a functional water channel into salivary epithelial cells in vitro and in vivo.
Academic Article	Cloning and characterization of adeno-associated virus type 5.
Academic Article	Adeno-associated virus (AAV) type 5 Rep protein cleaves a unique terminal resolution site compared with other AAV serotypes.
Academic Article	Glucose- and metabolically regulated hepatic insulin gene therapy for diabetes.
Academic Article	Determination of adeno-associated virus Rep68 and Rep78 binding sites by random sequence oligonucleotide selection.
Academic Article	Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.
Academic Article	Toward exascale production of recombinant adeno-associated virus for gene transfer applications.
Academic Article	Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.
Academic Article	Serum-free production and column purification of adeno-associated virus type 5.
Academic Article	An adeno-associated virus (AAV) initiator protein, Rep78, catalyzes the cleavage and ligation of single-stranded AAV ori DNA.
Academic Article	Adeno-associated virus type 5: transduction efficiency and cell-type specificity in the primate retina.
Academic Article	Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer.
Academic Article	Chromatography-based purification of adeno-associated virus.
Academic Article	The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Academic Article	Adeno-associated virus type 2 Rep78 induces apoptosis through caspase activation independently of p53.
Academic Article	Strategies for manufacturing recombinant adeno-associated virus vectors for gene therapy applications exploiting baculovirus technology.
Academic Article	Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein.
Academic Article	Large-scale production of recombinant adeno-associated viral vectors.
Academic Article	Glucose-responsive gene delivery in pancreatic Islet cells via recombinant adeno-associated viral vectors.
Academic Article	Sequence requirements for stable binding and function of Rep68 on the adeno-associated virus type 2 inverted terminal repeats.
Academic Article	Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.
Academic Article	The regulatory rep protein of adeno-associated virus binds to sequences within the c-H-ras promoter.
Academic Article	Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma.
Academic Article	Prospects for the use of adeno-associated virus as a vector for human gene therapy.
Academic Article	Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA.
Academic Article	Adeno-associated virus DNA replication in vitro: activation by a maltose binding protein/Rep 68 fusion protein.
Academic Article	Reproducible high yields of recombinant adeno-associated virus produced using invertebrate cells in 0.02- to 200-liter cultures.
Academic Article	Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter.
Academic Article	Biologically active Rep proteins of adeno-associated virus type 2 produced as fusion proteins in Escherichia coli.
Academic Article	Large-scale recombinant adeno-associated virus production.
Academic Article	Production and characterization of novel recombinant adeno-associated virus replicative-form genomes: a eukaryotic source of DNA for gene transfer.
Academic Article	Site-specific integration by adeno-associated virus.
Academic Article	Adeno-associated virus type 2 Rep78 inhibition of PKA and PRKX: fine mapping and analysis of mechanism.
Academic Article	Recombinant adeno-associated virus serotype 2 vectors mediate stable interleukin 10 secretion from salivary glands into the bloodstream.
Academic Article	High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors.
Academic Article	The roles of AAV Rep proteins in gene expression and targeted integration.
Academic Article	The DNA minor groove binding agents Hoechst 33258 and 33342 enhance recombinant adeno-associated virus (rAAV) transgene expression.
Academic Article	Development of recombinant adeno-associated virus vectors carrying small interfering RNA (shHec1)-mediated depletion of kinetochore Hec1 protein in tumor cells.
Academic Article	Recombinant adeno-associated virus serotypes 2- and 5-mediated gene transfer in the mammalian brain: quantitative analysis of heparin co-infusion.
Academic Article	Organization of adeno-associated virus DNA in latently infected Detroit 6 cells.
Academic Article	Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.
Academic Article	A simplified baculovirus-AAV expression vector system coupled with one-step affinity purification yields high-titer rAAV stocks from insect cells.
Academic Article	Producing recombinant adeno-associated virus in foster cells: overcoming production limitations using a baculovirus-insect cell expression strategy.
Academic Article	Regulation of adeno-associated virus DNA replication.
Academic Article	Recombinant adeno-associated virus vector for gene transfer to the transplanted rat heart.
Academic Article	Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping.
Academic Article	Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.
Academic Article	The Rep78 gene product of adeno-associated virus (AAV) self-associates to form a hexameric complex in the presence of AAV ori sequences.
Academic Article	Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain.
Academic Article	Transposase-mediated construction of an integrated adeno-associated virus type 5 helper plasmid.
Academic Article	Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep.
Academic Article	Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts.
Academic Article	Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles.
Academic Article	Gene transfer of the costimulatory molecules B7-1 and B7-2 into human multiple myeloma cells by recombinant adeno-associated virus enhances the cytolytic T cell response.
Academic Article	Production of recombinant adeno-associated vectors using two bioreactor configurations at different scales.
Academic Article	Insect cells as a factory to produce adeno-associated virus type 2 vectors.
Academic Article	Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients.
Academic Article	In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.
Academic Article	Germline viral "fossils" guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus.
Academic Article	Manufacturing Clinical Grade Recombinant Adeno-Associated Virus Using Invertebrate Cell Lines.
Academic Article	Recombinant Adeno-Associated Virus Quality Control for Non-Clinical and Clinical Vectors: How an Unregulated Commercial Sector Can Compromise Development of New Gene Therapies.
Academic Article	Mechanistic modeling explains the production dynamics of recombinant adeno-associated virus with the baculovirus expression vector system.
Academic Article	Selective Enrichment of Full Capsids of Adeno-Associated Virus.

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Dependovirus