| Item Type | Name |
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Academic Article
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The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance.
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Academic Article
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Infections of people with complement deficiencies and patients who have undergone splenectomy.
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Academic Article
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Meningococcal group W-135 and Y capsular polysaccharides paradoxically enhance activation of the alternative pathway of complement.
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Academic Article
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Enhanced bacteremia in human factor H transgenic rats infected by Neisseria meningitidis.
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Academic Article
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The relative roles of factor H binding protein, neisserial surface protein A, and lipooligosaccharide sialylation in regulation of the alternative pathway of complement on meningococci.
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Academic Article
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Phosphoethanolamine residues on the lipid A moiety of Neisseria gonorrhoeae lipooligosaccharide modulate binding of complement inhibitors and resistance to complement killing.
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Academic Article
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Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci.
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Academic Article
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Heptose I glycan substitutions on Neisseria gonorrhoeae lipooligosaccharide influence C4b-binding protein binding and serum resistance.
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Academic Article
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Defining targets for complement components C4b and C3b on the pathogenic neisseriae.
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Academic Article
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Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum.
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Academic Article
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Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin.
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Academic Article
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The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.
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Concept
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Complement C3b Inactivator Proteins
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Concept
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Complement C4b-Binding Protein
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Concept
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Complement C3-C5 Convertases, Alternative Pathway
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Concept
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Complement Pathway, Classical
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Concept
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Complement C3a
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Concept
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Complement Factor H
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Concept
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Complement System Proteins
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Concept
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Complement C4
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Concept
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Complement C1
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Concept
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Complement C3b
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Concept
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Complement Activation
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Concept
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Complement Pathway, Alternative
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Concept
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Complement C4b
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Concept
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Complement C3
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Academic Article
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Meningococcal disease and the complement system.
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Academic Article
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Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis.
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Academic Article
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Inhibition of the alternative pathway of nonhuman infant complement by porin B2 contributes to virulence of Neisseria meningitidis in the infant rat model.
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Academic Article
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a-2,3-sialyltransferase expression level impacts the kinetics of lipooligosaccharide sialylation, complement resistance, and the ability of Neisseria gonorrhoeae to colonize the murine genital tract.
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Academic Article
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Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics.
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Academic Article
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A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
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Academic Article
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Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae.
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Academic Article
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Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics.
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Academic Article
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Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against Neisseria gonorrhoeae.
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Academic Article
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Role of Gonococcal Neisserial Surface Protein A (NspA) in Serum Resistance and Comparison of Its Factor H Binding Properties with Those of Its Meningococcal Counterpart.
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Academic Article
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A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine.
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Academic Article
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Effect of a C1s Inhibitor on the Efficacy of Anti-Capsular Antibodies against Neisseria meningitidis and Streptococcus pneumoniae.
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Academic Article
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Complement interactions with the pathogenic Neisseriae: clinical features, deficiency states, and evasion mechanisms.
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Academic Article
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Therapeutic CMP-Nonulosonates against Multidrug-Resistant Neisseria gonorrhoeae.
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Academic Article
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Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins.
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Academic Article
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Efficacy of an Experimental Gonococcal Lipooligosaccharide Mimitope Vaccine Requires Terminal Complement.
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Academic Article
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Alternative pathway amplification and infections.
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Academic Article
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An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae.
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