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Search Results to Ricardo T Gazzinelli DSc, DVM

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One or more keywords matched the following properties of Gazzinelli, Ricardo

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keywords Monocyte-Derived Dendritic Cells
overview

Research:

My research program is developed at the Division of Infectious Diseases and Immunology, Department of Medicine, UMASS Medical School, Worcester, USA and at Oswaldo Cruz Foundation-Minas, in belo Horizonte, Brazil.

Broadly, I am interested in understanding the immunological mechanisms that warrant host resistance to infection and at the same time prevent immune mediated tissue damage and pathology in parasitic diseases. The main areas of scientific research carried in my lab are on: (i) the role innate immunity on host resistance and pathogenesis to infection with protozoan parasites; (ii) the mechanisms of cytotoxic T cells in resistance to infection; and (iii) the development of recombinant vaccines that induce cell-mediated immunity and protect against protozoan infections. When possible, we try to address our questions regarding host-parasite interactions, employing cellular systems, experimental rodent models and well-characterized patients undergoing specific protozoan infection.

Main Projects:

Role of TLRs, inflammasome and inflammatory caspses in malaria pathogenesis

Role of monocyte-derived dendritic cells in malária

The influence of the circadian cycle on inflammation, metabolismo and Plasmodium infection

The role of IRAKs and Myddosomes in infection with T. gondii

Development of the recombinant-A2 vaccine for visceral leishmaniasis

Development of the recombinant-ASP2/TS vaccine for visceral leishmaniasis

My current research is supported by Conselho Nacional de Desenvolvimento Cinetifico e Tecnologico (CNPq), Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG) and the National Institutes of Health (NIH).

Post Docs

Fiocruz-Minas

Caroline Junqueira, PhD - Staff Scientist

  • Camila Brabosa, PhD student - Mapping of CD8 T cell-specifc Epitopes from Malaria Blood Stage
  • Gregorio Almeida, DVM, PhD - Immunology of Asymptomatic Malaria
  • Guilherme Maia, PhD - Innate Lymphocytes in Malaria
  • Isabella Hirako, PhD - Monocyte-Derived Dendritic Cells in Malaria
  • Júlia Castro, MSc student - Chagas Disease Vaccine
  • Larissa Pereira, MSc student - Inflammatory Caspases in Malaria
  • Kely Mateucci, PhD - Monocyte-Derived Dendritic Cells Metabolism in Malaria
  • Milton Pereira, PhD - Caspases and inflammasomes in Malaria and Chagas Disease
  • Natalia Satchiko Souza, PhD - CD8+ T cells in malaria

UMASS

  • Danielle Durso, PhD - IRAKs and Myddosomes in host resistance to T. gondii
  • Patricia Assis, PhD - Host Clock genes and Malaria
  • Ogooluwa Ojelabi, PhD - Glucose Metabolism and Malaria

Search Criteria
  • Monocytes