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Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.
Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
UNC93B1 mediates host resistance to infection with Toxoplasma gondii.
Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria.
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.
UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
Toll-Like Receptor 4
Toll-Like Receptor 9
Toll-Like Receptor 3
Toll-Like Receptor 2
Toll-Like Receptor 7
Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
The immunology of Plasmodium vivax malaria.
Caspase-8 mediates inflammation and disease in rodent malaria.
?-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model.
Toll Like Receptors