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Zhu, Lihua

One or more keywords matched the following items that are connected to Zhu, Lihua

Item Type	Name
Academic Article	CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems.
Academic Article	DNA-binding-domain fusions enhance the targeting range and precision of Cas9.
Academic Article	Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.
Academic Article	GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases.
Academic Article	CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy.
Academic Article	Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Academic Article	Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
Academic Article	Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing.
Academic Article	Enhanced Cas12a editing in mammalian cells and zebrafish.
Academic Article	Genome-wide detection and analysis of CRISPR-Cas off-targets.
Concept	CRISPR-Cas Systems
Academic Article	Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.
Academic Article	Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.

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CRISPR Cas Systems