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Kelliher, Michelle

One or more keywords matched the following items that are connected to Kelliher, Michelle

Item Type	Name
Academic Article	Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.
Academic Article	The death domain kinase RIP mediates the TNF-induced NF-kappaB signal.
Academic Article	Calorie restriction, stress and the ubiquitin-dependent pathway in mouse livers.
Academic Article	The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation.
Academic Article	The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase.
Academic Article	Aging, calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice.
Academic Article	Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.
Academic Article	RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.
Academic Article	The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.
Academic Article	TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.
Academic Article	RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation.
Academic Article	p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice.
Academic Article	Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination.
Academic Article	The Notch1/c-Myc pathway in T cell leukemia.
Academic Article	Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.
Academic Article	Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.
Academic Article	RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
Academic Article	The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice.
Academic Article	NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.
Academic Article	A DNA-binding mutant of TAL1 cooperates with LMO2 to cause T cell leukemia in mice.
Academic Article	A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage.
Academic Article	Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
Academic Article	Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.
Academic Article	The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death.
Academic Article	TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia.
Academic Article	RIP1-driven autoinflammation targets IL-1a independently of inflammasomes and RIP3.
Academic Article	The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia.
Academic Article	NF-kappaB activation in premalignant mouse tal-1/scl thymocytes and tumors.
Academic Article	The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase.
Academic Article	Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.
Academic Article	Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Academic Article	Activating Notch1 mutations in mouse models of T-ALL.
Academic Article	NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells.
Academic Article	Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Academic Article	NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.
Academic Article	Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Academic Article	Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide.
Academic Article	Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Academic Article	The TLX1 oncogene drives aneuploidy in T cell transformation.
Academic Article	Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Academic Article	Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.
Academic Article	ABL oncogenes directly stimulate two distinct target cells in bone marrow from 5-fluorouracil-treated mice.
Concept	Membrane Proteins
Concept	Protein Binding
Concept	DNA-Binding Proteins
Concept	Oncogene Proteins, Fusion
Concept	Amyloid beta-Protein Precursor
Concept	Protein Processing, Post-Translational
Concept	Tumor Suppressor Protein p14ARF
Concept	Ubiquitin-Protein Ligases
Concept	Proto-Oncogene Proteins c-rel
Concept	Phosphate-Binding Proteins
Concept	Unfolded Protein Response
Concept	Tumor Suppressor Protein p53
Concept	Proto-Oncogene Protein c-fli-1
Concept	Mitogen-Activated Protein Kinases
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Retinoblastoma Protein
Concept	Hedgehog Proteins
Concept	Protein Tyrosine Phosphatase, Non-Receptor Type 6
Concept	Protein Kinase Inhibitors
Concept	Mitogen-Activated Protein Kinase 1
Concept	Oncogene Proteins
Concept	Carrier Proteins
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Chromosomal Proteins, Non-Histone
Concept	Cell Cycle Proteins
Concept	Protein Biosynthesis
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Protein Kinases
Concept	Fusion Proteins, bcr-abl
Concept	GTP-Binding Protein alpha Subunits, Gs
Concept	Intracellular Signaling Peptides and Proteins
Concept	BH3 Interacting Domain Death Agonist Protein
Concept	tau Proteins
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Viral Proteins
Concept	Repressor Proteins
Concept	HSP90 Heat-Shock Proteins
Concept	Proto-Oncogene Proteins c-myb
Concept	RNA-Binding Protein EWS
Concept	Nod2 Signaling Adaptor Protein
Concept	Proto-Oncogene Proteins c-akt
Concept	Proteins
Concept	Fas-Associated Death Domain Protein
Concept	F-Box Proteins
Concept	Receptor-Interacting Protein Serine-Threonine Kinases
Concept	Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Concept	Homeodomain Proteins
Concept	Membrane Transport Proteins
Concept	Protein Structure, Tertiary
Concept	Adaptor Proteins, Signal Transducing
Concept	Proto-Oncogene Proteins c-myc
Concept	Protein Multimerization
Concept	Green Fluorescent Proteins
Concept	Bacterial Proteins
Concept	Recombinant Fusion Proteins
Concept	Protein Stability
Concept	Amyloid Precursor Protein Secretases
Concept	Neoplasm Proteins
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Wnt Proteins
Concept	I-kappa B Proteins
Concept	bcl-X Protein
Concept	Adenovirus E2 Proteins
Concept	Viral Matrix Proteins
Concept	Adaptor Proteins, Vesicular Transport
Concept	Apoptosis Regulatory Proteins
Concept	Nod1 Signaling Adaptor Protein
Concept	Proto-Oncogene Proteins
Concept	Proto-Oncogene Proteins c-abl
Concept	GTPase-Activating Proteins
Concept	Tumor Suppressor Proteins
Concept	Receptor-Interacting Protein Serine-Threonine Kinase 2
Concept	SUMO-1 Protein
Academic Article	Activation of NOD receptors by Neisseria gonorrhoeae modulates the innate immune response.
Academic Article	c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Academic Article	An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Academic Article	Leukemia propagating cells Akt up.
Academic Article	Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Academic Article	RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
Academic Article	NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro.
Academic Article	Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
Academic Article	Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.
Academic Article	Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.
Academic Article	RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Academic Article	RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Academic Article	Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.
Academic Article	Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice.
Academic Article	NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
Academic Article	NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-?B-Dependent and -Independent Functions.
Academic Article	The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Academic Article	The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis.
Academic Article	CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.
Academic Article	RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.
Academic Article	RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Academic Article	High-Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML.
Academic Article	Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
Academic Article	CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells.
Academic Article	Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
Academic Article	JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.
Academic Article	Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-? Synthesis Induced by Lipopolysaccharide.
Academic Article	RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia.
Academic Article	ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data.
Academic Article	RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome.
Academic Article	Dysfunctional intracellular calcium homoeostasis: a central cause of neurodegeneration in Alzheimer's disease.
Academic Article	Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia.
Academic Article	The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.
Academic Article	Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Academic Article	RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Academic Article	Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Academic Article	UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response.
Academic Article	Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.
Academic Article	NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263.
Academic Article	Analyzing Necroptosis Using an RIPK1 Kinase Inactive Mouse Model of TNF Shock.
Academic Article	BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Academic Article	BID-ding on necroptosis in MDS.
Academic Article	RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-?B Activation.
Academic Article	Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Academic Article	Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke.
Academic Article	Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.
Academic Article	T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
Concept	NLR Family, Pyrin Domain-Containing 3 Protein
Concept	Nanog Homeobox Protein
Concept	Bcl-2-Like Protein 11
Concept	Tumor Necrosis Factor alpha-Induced Protein 3
Concept	T-Cell Acute Lymphocytic Leukemia Protein 1
Concept	F-Box-WD Repeat-Containing Protein 7
Concept	WNK Lysine-Deficient Protein Kinase 1
Concept	Protein-Arginine Deiminases
Concept	Transcription Factor 7-Like 1 Protein
Concept	LIM Domain Proteins
Concept	Ataxia Telangiectasia Mutated Proteins
Concept	Myeloid Cell Leukemia Sequence 1 Protein
Academic Article	Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.
Academic Article	TBK1 inhibition unleashes RIPK1, resensitizing tumors to immunotherapy.
Academic Article	ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice.
Academic Article	The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance.
Academic Article	Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma.
Academic Article	Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia.
Academic Article	Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
Academic Article	The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma.
Academic Article	Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.

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GTP Binding Proteins