Please visit the Kelliher Lab website at: http://labs.umassmed.edu/kelliherlab/ to learn more about our current research areas.
1. Identify genes/pathways that mediate leukemia-initiating cell survival
2. Understand the molecular basis of glucocorticoid resistance in leukemia
3. Examine contribution of RIPK1 kinase in inflammatory and autoimmune disease mouse models.
4. Reveal tissue-specific roles for RIPK1 in cell death and inflammation. Use conditional Ripk1 allele to investigate effects of Ripk1 deletion in liver, pancreas and antigen presenting cells.