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Gao, Guangping

One or more keywords matched the following properties of Gao, Guangping

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phone	508-856-3563

One or more keywords matched the following items that are connected to Gao, Guangping

Item Type	Name
Academic Article	Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production.
Academic Article	rAAV9--a human-derived adeno-associated virus vector for efficient transgene expression in mouse cingulate cortex.
Academic Article	MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression.
Academic Article	Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system.
Academic Article	Exploiting natural diversity of AAV for the design of vectors with novel properties.
Academic Article	Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.
Academic Article	Gene transfer in the lung using recombinant adeno-associated virus.
Academic Article	SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified M?ller cell-induced rabbit models.
Academic Article	Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus.
Academic Article	Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction.
Academic Article	Vector sequences are not detected in tumor tissue from research subjects with ornithine transcarbamylase deficiency who previously received adenovirus gene transfer.
Academic Article	Transendocardial delivery of AAV6 results in highly efficient and global cardiac gene transfer in rhesus macaques.
Academic Article	Production and discovery of novel recombinant adeno-associated viral vectors.
Academic Article	Retinal gene delivery by rAAV and DNA electroporation.
Academic Article	Gene therapy for Canavan's disease takes a step forward.
Academic Article	Gene transfer to the CNS using recombinant adeno-associated virus.
Academic Article	Gene transfer in the liver using recombinant adeno-associated virus.
Concept	Angiogenesis Inhibitors
Concept	Vascular Endothelial Growth Factor A
Concept	Ornithine Carbamoyltransferase
Concept	Disease Models, Animal
Concept	Fibroblasts
Concept	Injections, Intramuscular
Concept	Targeted Gene Repair
Concept	Retinal Pigment Epithelium
Concept	Inverted Repeat Sequences
Concept	Virus Cultivation
Concept	Sequence Analysis, DNA
Concept	Spastic Paraplegia, Hereditary
Concept	PPAR alpha
Concept	Brain Neoplasms
Concept	Osteoclasts
Concept	Interferon-beta
Concept	Prefrontal Cortex
Concept	Bone Resorption
Concept	Blood-Brain Barrier
Concept	Myelin Sheath
Concept	Cell Lineage
Concept	Nicotine
Concept	Humans
Concept	Animals, Newborn
Concept	Mitochondria
Concept	Prostatic Neoplasms
Concept	HeLa Cells
Concept	Heterozygote
Concept	Genetic Therapy
Concept	Osteocytes
Concept	Cilia
Concept	Cell Division
Concept	Gene Expression
Concept	Genes, MHC Class II
Concept	Papillomavirus Infections
Concept	Mutagenesis, Site-Directed
Concept	Terminal Repeat Sequences
Concept	Cats
Concept	RNA Interference
Concept	Colposcopy
Concept	Histone Deacetylase 1
Concept	Gyrus Cinguli
Concept	Mice, Inbred BALB C
Concept	Alveolar Bone Loss
Concept	Habenula
Concept	RNA Editing
Concept	Mice, Obese
Concept	Influenza A Virus, H1N1 Subtype
Concept	Wool
Concept	Amyotrophic Lateral Sclerosis
Concept	Hereditary Sensory and Autonomic Neuropathies
Concept	Ribonuclease III
Concept	Leber Congenital Amaurosis
Concept	Down-Regulation
Concept	Electroporation
Concept	Injections
Concept	Dependovirus
Concept	Treatment Outcome
Concept	Acetyl-CoA Carboxylase
Concept	Endonucleases
Concept	Osteoblasts
Concept	Amidohydrolases
Concept	China
Concept	X-Ray Diffraction
Concept	Canavan Disease
Concept	Palmitates
Concept	Sterol Regulatory Element Binding Protein 1
Concept	Encephalomyelitis, Autoimmune, Experimental
Concept	Osteogenesis
Concept	Adenosine Triphosphate
Concept	Drug Delivery Systems
Concept	Random Allocation
Concept	Mice, Knockout
Concept	Baculoviridae
Concept	Oxidative Phosphorylation
Concept	Acetyl Coenzyme A
Concept	Antiviral Agents
Concept	Mesencephalon
Concept	Colorectal Neoplasms
Concept	CHO Cells
Concept	Infusion Pumps, Implantable
Concept	Heart Failure
Concept	Cricetulus
Concept	Pneumonia, Viral
Concept	AMP-Activated Protein Kinases
Concept	Fallopian Tubes
Concept	Infusions, Intravenous
Concept	Ornithine Carbamoyltransferase Deficiency Disease
Concept	Up-Regulation
Concept	Obesity
Concept	Energy Metabolism
Concept	Monomeric GTP-Binding Proteins
Concept	Mice
Concept	Clinical Trials as Topic
Concept	Mucopolysaccharidosis VII
Concept	Insulin Resistance
Concept	Epilepsy
Concept	Thalamus
Concept	Blastocyst
Concept	Electrons
Concept	Adiponectin
Concept	Gene Expression Regulation, Developmental
Concept	ATP Citrate (pro-S)-Lyase
Concept	Cattle
Concept	Transgenes
Concept	Diabetes Mellitus, Type 2
Concept	Mice, Inbred C57BL
Concept	Congenital Disorders of Glycosylation
Concept	Haloperidol
Concept	Gene Expression Regulation
Concept	Computational Biology
Concept	Sequence Deletion
Concept	Prostate
Concept	Caudate Nucleus
Concept	Mutation
Concept	Cells, Cultured
Concept	Liver Neoplasms
Concept	Mice, Transgenic
Concept	Uterine Cervical Neoplasms
Concept	Ubiquinone
Concept	Huntington Disease
Concept	Containment of Biohazards
Concept	Oxygen
Concept	Capsid
Concept	Sheep, Domestic
Concept	Activins
Concept	Injections, Intraocular
Concept	Rod Cell Outer Segment
Concept	Nucleic Acid Conformation
Concept	Xenograft Model Antitumor Assays
Concept	beta Catenin
Concept	alpha 1-Antitrypsin
Concept	Vaccines
Concept	Primates
Concept	DNA, Viral
Concept	Genetic Diseases, Inborn
Concept	Early Detection of Cancer
Concept	Rabbits
Concept	Sirtuin 1
Concept	Codon, Terminator
Concept	Adaptor Proteins, Signal Transducing
Concept	Receptors, Complement 3b
Concept	Genetic Engineering
Concept	Electrophoresis, Agar Gel
Concept	Macaca mulatta
Concept	Tyrosinemias
Concept	DEAD-box RNA Helicases
Concept	Vero Cells
Concept	Genes, Reporter
Concept	Synapses
Concept	Uterine Cervical Dysplasia
Concept	Cerebrospinal Fluid
Concept	Cryoelectron Microscopy
Concept	Corticotropin-Releasing Hormone
Concept	Retina
Concept	Epigenesis, Genetic
Concept	Survival Analysis
Concept	Arthritis, Rheumatoid
Concept	ATP-Binding Cassette Transporters
Concept	Electrolytes
Concept	Green Fluorescent Proteins
Concept	Gene Order
Concept	Recombinant Fusion Proteins
Concept	Osteogenesis Imperfecta
Concept	Interleukin-1beta
Concept	Sheep
Concept	Cocaine
Concept	Sequence Alignment
Concept	Fibroblast Growth Factors
Concept	Influenza Vaccines
Concept	Maple Syrup Urine Disease
Concept	Transduction, Genetic
Concept	Carcinoma, Hepatocellular
Concept	Receptors, Corticotropin-Releasing Hormone
Concept	Papillomaviridae
Concept	Internal Capsule
Concept	Mice, Nude
Concept	Adenoviridae
Concept	Case-Control Studies
Concept	Muscular Atrophy, Spinal
Concept	Histocompatibility Antigens Class II
Concept	Gene Expression Regulation, Neoplastic
Concept	Reproducibility of Results
Concept	Fumarates
Concept	Clozapine
Concept	Foam Cells
Concept	Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
Concept	Mucopolysaccharidosis II
Concept	Electron Transport
Concept	Stem Cell Transplantation
Concept	Malonyl Coenzyme A
Concept	Antigen-Presenting Cells
Concept	Cross-Sectional Studies
Concept	Rats
Concept	PPAR gamma
Concept	Succinate Dehydrogenase
Concept	alpha 1-Antitrypsin Deficiency
Concept	Vitreous Body
Concept	Codon, Nonsense
Concept	Neostriatum
Concept	Retinal Cone Photoreceptor Cells
Concept	DNA Replication
Concept	Multiple Sclerosis
Concept	RNA Splicing
Concept	Callithrix
Concept	Cell Line
Concept	Transfection
Concept	Coronavirus Infections
Concept	Polymerase Chain Reaction
Concept	Severe Acute Respiratory Syndrome
Concept	Host-Pathogen Interactions
Concept	Corpus Striatum
Concept	Serotyping
Concept	Gene Deletion
Concept	Cholesterol
Concept	Complement C3
Concept	Genetic Vectors
Concept	Putamen
Concept	Ventral Tegmental Area
Concept	MicroRNAs
Concept	Hydrogen-Ion Concentration
Concept	Adipocytes
Concept	MAP Kinase Kinase 4
Concept	Promoter Regions, Genetic
Concept	Gene Silencing
Concept	Gene Knockout Techniques
Concept	Base Sequence
Concept	Alleles
Concept	Plasmids
Concept	Genes, Recessive
Concept	Follow-Up Studies
Concept	Gene Knockdown Techniques
Concept	Embryonic Development
Concept	3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Concept	Genome, Viral
Concept	Immunohistochemistry
Concept	Glioblastoma
Concept	Injections, Intravenous
Concept	CD36 Antigens
Concept	Gene Transfer Techniques
Concept	Cytomegalovirus
Concept	Cell Line, Tumor
Concept	Molecular Sequence Data
Concept	Osmotic Pressure
Concept	Choroidal Neovascularization
Academic Article	Prefrontal cortical dysfunction after overexpression of histone deacetylase 1.
Academic Article	A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.
Academic Article	Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival.
Academic Article	The potential of adeno-associated viral vectors for gene delivery to muscle tissue.
Academic Article	Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10.
Academic Article	State-of-the-art human gene therapy: part I. Gene delivery technologies.
Academic Article	The PPARa-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway.
Academic Article	State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications.
Academic Article	Adeno-associated virus-mediated microRNA delivery and therapeutics.
Academic Article	Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal.
Academic Article	Stability and compatibility of recombinant adeno-associated virus under conditions commonly encountered in human gene therapy trials.
Academic Article	Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.
Academic Article	Making the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades.
Academic Article	Gene Therapy for the Treatment of Neurological Disorders: Metabolic Disorders.
Academic Article	Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.
Academic Article	Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Academic Article	Adeno-associated Virus Serotype Vectors Efficiently Transduce Normal Prostate Tissue and Prostate Cancer Cells.
Academic Article	Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
Academic Article	Widespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector.
Academic Article	rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.
Academic Article	Systemic AAV9-IFN? gene delivery treats highly invasive glioblastoma.
Academic Article	Empty Virions In AAV8 Vector Preparations Reduce Transduction Efficiency And May Cause Total Viral Particle Dose-Limiting Side-Effects.
Academic Article	Examination of the Blood Brain Barrier integrity in a mouse model of the neurodegenerative Canavan's disease.
Academic Article	Intracranial AAV-IFN-? gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model.
Academic Article	The Sodium Channel ?4 Auxiliary Subunit Selectively Controls Long-Term Depression in Core Nucleus Accumbens Medium Spiny Neurons.
Academic Article	Fat mass and obesity-associated protein attenuates lipid accumulation in macrophage foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice.
Academic Article	Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection.
Academic Article	Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity.
Academic Article	A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates.
Academic Article	Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras.
Academic Article	MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and?Patients From Ethanol-Induced Liver Disease.
Academic Article	Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice.
Academic Article	In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency.
Academic Article	Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space.
Academic Article	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses.
Academic Article	Taking a Hint from Structural Biology: To Better Understand AAV Transport across the BBB.
Academic Article	Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer.
Academic Article	Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Academic Article	Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs.
Academic Article	Selective Neuronal Uptake and Distribution of AAVrh8, AAV9, and AAVrh10 in Sheep After Intra-Striatal Administration.
Academic Article	Gene Therapy Using a miniCEP290 Fragment Delays Photoreceptor Degeneration in a Mouse Model of Leber Congenital Amaurosis.
Academic Article	Evaluation of portable colposcopy and human papillomavirus testing for screening of cervical cancer in rural China.
Academic Article	Adeno-associated virus vector as a platform for gene therapy delivery.
Academic Article	Intravenous Infusion of AAV for Widespread Gene Delivery to the Nervous System.
Academic Article	High-Throughput Quantification of In Vivo Adeno-Associated Virus Transduction with Barcoded Non-Coding RNAs.
Academic Article	Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis.
Academic Article	Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function.
Academic Article	Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno-Associated Virus.
Academic Article	Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold.
Academic Article	Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.
Academic Article	CRISPR-Based Therapeutic Genome Editing: Strategies and In?Vivo Delivery by AAV Vectors.
Academic Article	Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy.
Academic Article	Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.
Academic Article	AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity.
Academic Article	Is smaller better? Vaccine targeting recombinant receptor-binding domain might hold the key for mass production of effective prophylactics to fight the COVID-19 pandemic.
Academic Article	Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus.
Academic Article	A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21.
Academic Article	AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies.
Academic Article	Viral vector platforms within the gene therapy landscape.
Academic Article	Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
Academic Article	Canavan Disease as a Model for Gene Therapy-Mediated Myelin Repair.
Academic Article	Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction.
Academic Article	Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?
Academic Article	Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis.
Academic Article	AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.
Academic Article	Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.
Academic Article	Modulating immune responses to AAV by expanded polyclonal T-regs and capsid specific chimeric antigen receptor T-regulatory cells.
Concept	Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Concept	Gene Editing
Concept	Memory, Long-Term
Concept	HEK293 Cells
Concept	Infusions, Intraventricular
Concept	High-Throughput Nucleotide Sequencing
Concept	Diet, High-Fat
Concept	Nonsense Mediated mRNA Decay
Concept	Transcriptome
Concept	Plaque, Atherosclerotic
Concept	Intravitreal Injections
Concept	Pandemics
Concept	Cellular Microenvironment
Concept	Real-Time Polymerase Chain Reaction
Concept	Non-alcoholic Fatty Liver Disease
Concept	DNA End-Joining Repair
Concept	Recombinational DNA Repair
Concept	Infusions, Spinal
Concept	Clustered Regularly Interspaced Short Palindromic Repeats
Concept	CRISPR-Cas Systems
Concept	ATP Binding Cassette Transporter 1
Concept	Interpeduncular Nucleus
Academic Article	Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes.
Academic Article	Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.
Academic Article	AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice.
Academic Article	Durability of transgene expression after rAAV gene therapy.
Academic Article	Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector.
Academic Article	Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes.
Academic Article	Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.
Academic Article	Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery.
Academic Article	AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy.
Academic Article	Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
Academic Article	Ocular Drug Delivery: Advancements and Innovations.
Academic Article	WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects.
Academic Article	Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Academic Article	Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo.
Academic Article	Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis.
Academic Article	Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope.
Academic Article	Renewal of oligodendrocyte lineage reverses dysmyelination and CNS neurodegeneration through corrected N-acetylaspartate metabolism.
Academic Article	Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing.
Academic Article	AAV-Mediated Targeting of the Activin A-ACVR1R206H Signaling in Fibrodysplasia Ossificans Progressiva.
Academic Article	Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice.
Academic Article	Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo.
Academic Article	A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors.
Academic Article	AAV-based gene editing of type 1 collagen mutation to treat osteogenesis imperfecta.
Academic Article	Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope.
Academic Article	Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor.
Academic Article	Development of AAV-Mediated Gene Therapy Approaches to Treat Skeletal Diseases.
Academic Article	Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection.
Academic Article	Adeno-associated virus as a delivery vector for gene therapy of human diseases.
Academic Article	Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus.
Academic Article	AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys.
Academic Article	Engineering a targeted and safe bone anabolic gene therapy to treat osteoporosis in alveolar bone loss.
Academic Article	Developing AAV-delivered nonsense suppressor tRNAs for neurological disorders.
Academic Article	Systemic gene therapy corrects the neurological phenotype in a mouse model of NGLY1 deficiency.
Academic Article	The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2.
Academic Article	Recombinant adeno-associated virus as a delivery platform for ocular gene therapy: A comprehensive review.
Academic Article	Rhodoquinone carries electrons in the mammalian electron transport chain.
Academic Article	Comprehensive Review of Osteogenesis Imperfecta: Current Treatments and Future Innovations.
Academic Article	BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease.

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3
Methyl
2
Oxobutanoate
Dehydrogenase Lipoamide