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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway.
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled.
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd.
High bone density due to a mutation in LDL-receptor-related protein 5.
LDL-Receptor Related Proteins
Low Density Lipoprotein Receptor-Related Protein-6
Low Density Lipoprotein Receptor-Related Protein-5