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Brown, Robert

One or more keywords matched the following items that are connected to Brown, Robert

Item Type	Name
Academic Article	Motor unit number estimation predicts disease onset and survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Academic Article	Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.
Academic Article	T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.
Academic Article	Medicine. A reinnervating microRNA.
Academic Article	Dysferlin overexpression in skeletal muscle produces a progressive myopathy.
Academic Article	Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G??A transgenic ALS mice.
Academic Article	Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency.
Academic Article	Amyotrophic lateral sclerosis--a new role for old drugs.
Academic Article	Axonal transport defects in neurodegenerative diseases.
Concept	Disease Models, Animal
Academic Article	ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation.
Academic Article	Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.
Academic Article	Age-Dependent TDP-43-Mediated Motor Neuron Degeneration Requires GSK3, hat-trick, and xmas-2.
Academic Article	Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Academic Article	Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
Academic Article	Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
Academic Article	Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity.
Academic Article	Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Academic Article	A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
Academic Article	TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
Academic Article	Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis.
Academic Article	Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis.
Academic Article	Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis.
Academic Article	Finding a Treatment for ALS - Will Gene Editing Cut It?
Academic Article	Cortical Spreading Depression Denotes Concussion Injury.
Academic Article	BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
Academic Article	Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker.

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Disease Models Animal