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Brown, Robert

One or more keywords matched the following items that are connected to Brown, Robert

Item Type	Name
Academic Article	Comparison of incremental with multipoint MUNE methods in transgenic ALS mice.
Academic Article	Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice.
Academic Article	Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.
Academic Article	Motor unit number estimation predicts disease onset and survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Academic Article	Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.
Academic Article	Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats.
Academic Article	Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.
Academic Article	T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.
Academic Article	XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.
Academic Article	Medicine. A reinnervating microRNA.
Academic Article	Dysferlin overexpression in skeletal muscle produces a progressive myopathy.
Academic Article	Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G??A transgenic ALS mice.
Academic Article	A high-throughput screen to identify inhibitors of SOD1 transcription.
Academic Article	Mutant dynactin in motor neuron disease.
Academic Article	Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability.
Academic Article	Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration.
Academic Article	Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
Concept	Mice, Transgenic
Academic Article	Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.
Academic Article	Emerging mechanisms of molecular pathology in ALS.
Academic Article	Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Academic Article	Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
Academic Article	Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity.
Academic Article	Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Academic Article	A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
Academic Article	TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
Academic Article	Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis.
Academic Article	Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis.
Academic Article	Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis.
Academic Article	Finding a Treatment for ALS - Will Gene Editing Cut It?
Academic Article	Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease.
Academic Article	Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide.
Academic Article	Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker.
Academic Article	Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice.
Academic Article	Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo.
Academic Article	Genetic Ablation of Sarm1 Mitigates Disease Acceleration after Traumatic Brain Injury in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

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Mice Transgenic