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Search Results to David M Harlan MD

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One or more keywords matched the following items that are connected to Harlan, David

Item TypeName
Academic Article Islet-infiltrating t lymphocytes in insulin-dependent diabetic patients express CD80 (B7-1) and CD86 (B7-2).
Academic Article Low dose poly I:C prevents diabetes in the diabetes prone BB rat.
Academic Article Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent.
Academic Article Preclinical evaluation of tolerance induction protocols and islet transplantation in non-human primates.
Academic Article A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets.
Academic Article Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.
Academic Article Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.
Academic Article Sirolimus-induced interstitial pneumonitis in an islet transplant recipient.
Academic Article Gene-altered islets for transplant: giant leap or small step?
Academic Article Resistin serum levels in type 1 diabetes pre- and post-islet transplantation.
Academic Article Islet transplantation as a treatment for diabetes.
Academic Article Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154.
Academic Article Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.
Academic Article The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge.
Academic Article Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus.
Academic Article Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance.
Academic Article A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF.
Academic Article Immune intervention with anti-CD3 in diabetes.
Academic Article Radiologic aspects of islet cell transplantation.
Academic Article Assessment of islet function following islet and pancreas transplantation.
Academic Article Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation.
Academic Article Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function.
Academic Article Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.
Academic Article Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft.
Academic Article Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors.
Academic Article Counterpoint: clinical islet transplantation: not ready for prime time.
Academic Article Current advances and travails in islet transplantation.
Academic Article Islet cell allotransplantation as a model system for a bioengineering approach to reparative medicine: immunological concerns.
Academic Article Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site.
Academic Article Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway.
Academic Article Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression.
Academic Article Beta cell-specific CD80 (B7-1) expression disrupts tissue protection from autoantigen-specific CTL-mediated diabetes.
Academic Article Islet transplantation: where do we stand now?
Academic Article Resistin is expressed in pancreatic islets.
Academic Article State of the art: islet transplantation for the cure of type 1 diabetes mellitus.
Academic Article Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.
Academic Article A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice.
Academic Article Very-low-dose streptozotocin induces diabetes in insulin promoter-mB7-1 transgenic mice.
Academic Article Insulinomas and expression of an insulin splice variant.
Academic Article Pancreatic islet transplantation.
Academic Article Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging.
Academic Article Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute to significant islet cell regeneration once disease is established.
Academic Article Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.
Academic Article Dynamic changes in pancreatic endocrine cell abundance, distribution, and function in antigen-induced and spontaneous autoimmune diabetes.
Academic Article Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection.
Academic Article Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy.
Academic Article Humanized mice for the study of type 1 and type 2 diabetes.
Academic Article Extrapancreatic autoantibody profiles in type I diabetes.
Academic Article Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.
Concept Islets of Langerhans Transplantation
Concept Islets of Langerhans
Academic Article IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse.
Academic Article Editorial: diabetes and the endocrine pancreas I.
Academic Article Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.
Academic Article Novel Observations from Next Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets
Academic Article Long-term immunosuppression after solitary islet transplantation is associated with preserved C-peptide secretion for more than a decade.
Academic Article The MAFB transcription factor impacts islet a-cell function in rodents and represents a unique signature of primate islet ß-cells.
Academic Article Surprising Heterogeneity of Pancreatic Islet Cell Subsets.
Academic Article Response to Comment on Harlan. Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. Diabetes Care 2016;39:1072-1074.

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