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Tc1 and Tc2 effector cell therapy elicit long-term tumor immunity by contrasting mechanisms that result in complementary endogenous type 1 antitumor responses.
CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency.
Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms.
Heterogeneity of CD4(+) and CD8(+) T cells.
Uneven distribution of MHC class II epitopes within the influenza virus.
The immune system provides a strong response to even a low exposure to virus.
Memory CD4+ T cells induce innate responses independently of pathogen.
Memory CD4 T cell-mediated immunity against influenza A virus: more than a little helpful.
Multipronged CD4(+) T-cell effector and memory responses cooperate to provide potent immunity against respiratory virus.
Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates.
CD4 Positive T Lymphocytes