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One or more keywords matched the following items that are connected to Swain, Susan
Item TypeName
Academic Article Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals.
Academic Article TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation.
Academic Article From naive to memory T cells.
Academic Article Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements.
Academic Article Analysis of CD4+ T cells that provide contact-dependent bystander help to B cells.
Academic Article Antigen-independent changes in naive CD4 T cells with aging.
Academic Article Age-related changes in CD4 T cells of T cell receptor transgenic mice.
Academic Article Transferable anergy: superantigen treatment induces CD4+ T cell tolerance that is reversible and requires CD4-CD8- cells and interferon gamma.
Academic Article CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells.
Academic Article From naive to memory. Development and regulation of CD4+ T cell responses.
Academic Article Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor.
Academic Article Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis.
Academic Article Helper T cell memory: more questions than answers.
Academic Article Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.
Academic Article The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines.
Academic Article CD4 T-cell memory can persist in the absence of class II.
Academic Article Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals.
Academic Article Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells.
Academic Article Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation.
Academic Article The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments.
Academic Article Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma.
Academic Article B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activity.
Academic Article Regulation of T cell subsets from naive to memory.
Academic Article Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis.
Academic Article Regulation of the generation and maintenance of T-cell memory: a direct, default pathway from effectors to memory cells.
Academic Article CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly.
Academic Article CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency.
Academic Article IL-7: maintaining T-cell memory and achieving homeostasis.
Academic Article Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells.
Academic Article Repeated stimulation of CD4 effector T cells can limit their protective function.
Academic Article CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza.
Academic Article CD4 T cell-mediated protection from lethal influenza: perforin and antibody-mediated mechanisms give a one-two punch.
Academic Article Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation.
Academic Article Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice.
Academic Article IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge.
Academic Article Accumulation of NFAT mediates IL-2 expression in memory, but not na?ve, CD4+ T cells.
Academic Article IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals.
Academic Article Impact of post-thymic cellular longevity on the development of age-associated CD4+ T cell defects.
Academic Article Influencing the fates of CD4 T cells on the path to memory: lessons from influenza.
Academic Article SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation.
Academic Article Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses.
Academic Article Functionally diverse subsets in CD4 T cell responses against influenza.
Academic Article T-cell immunosenescence: lessons learned from mouse models of aging.
Academic Article Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects.
Academic Article The potential of CD4 T-cell memory.
Academic Article Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma.
Academic Article Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects.
Academic Article Hallmarks of CD4 T cell immunity against influenza.
Academic Article Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype.
Academic Article Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development.
Academic Article Control of innate immunity by memory CD4 T cells.
Academic Article Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms.
Academic Article Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors.
Academic Article IL-7 promotes the transition of CD4 effectors to persistent memory cells.
Academic Article Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin.
Academic Article Generation and in vivo persistence of polarized Th1 and Th2 memory cells.
Academic Article Effector functions of helper T cells.
Academic Article IL4 dictates T-cell differentiation.
Academic Article Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs.
Academic Article Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.
Academic Article Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease.
Academic Article Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen.
Academic Article T-cell memory: new perspectives.
Academic Article Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
Academic Article CD4 T cell responses to influenza infection.
Academic Article CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro.
Academic Article Homeostasis and the age-associated defect of CD4 T cells.
Academic Article Uneven distribution of MHC class II epitopes within the influenza virus.
Academic Article Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation.
Academic Article Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection.
Academic Article Rapid default transition of CD4 T cell effectors to functional memory cells.
Academic Article The effector to memory transition of CD4 T cells.
Academic Article IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.
Academic Article Memory CD4+ T cells induce innate responses independently of pathogen.
Academic Article Regulation of CD4+ T-cell contraction during pathogen challenge.
Academic Article TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism.
Academic Article Cytotoxic CD4 T cells in antiviral immunity.
Academic Article Expanding roles for CD4? T cells in immunity to viruses.
Academic Article Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection.
Academic Article Memory CD4 T cell-mediated immunity against influenza A virus: more than a little helpful.
Academic Article Multipronged CD4(+) T-cell effector and memory responses cooperate to provide potent immunity against respiratory virus.
Academic Article Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.
Academic Article Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines.
Academic Article Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.
Academic Article CD4 T cell development and cytokine polarization: an overview.
Concept CD4-Positive T-Lymphocytes
Academic Article CD4 T cell defects in the aged: causes, consequences and strategies to circumvent.
Academic Article Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2.
Academic Article IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age.
Academic Article Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection.
Academic Article PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
Academic Article Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza.
Academic Article Short-Lived Antigen Recognition but Not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells To Become Protective Memory.
Academic Article NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection.
Academic Article IL-15 supports the generation of protective lung-resident memory CD4 T cells.
Academic Article Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus.
Academic Article The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age.
Academic Article Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation.
Academic Article Virus-induced natural killer cell lysis of T cell subsets.
Academic Article CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation.
Academic Article Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production.
Academic Article Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates.
Academic Article Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection.
Academic Article Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza.
Academic Article CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated.
Academic Article Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15.
Academic Article CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint.
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  • CD4 Positive T Lymphocytes