| Item Type | Name |
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Academic Article
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Enhanced development of Th2-like primary CD4 effectors in response to sustained exposure to limited rIL-4 in vivo.
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Academic Article
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TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation.
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Academic Article
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From naive to memory T cells.
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Academic Article
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Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements.
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Academic Article
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Analysis of CD4+ T cells that provide contact-dependent bystander help to B cells.
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Academic Article
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Antigen-independent changes in naive CD4 T cells with aging.
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Academic Article
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Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.
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Academic Article
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CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells.
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Academic Article
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Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor.
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Academic Article
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Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.
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Academic Article
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E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination.
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Academic Article
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Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen.
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Academic Article
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Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells.
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Academic Article
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Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation.
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Academic Article
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Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma.
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Academic Article
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CD4 T cells in murine acquired immunodeficiency syndrome: polyclonal progression to anergy.
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Academic Article
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Reciprocal regulation of polarized cytokine production by effector B and T cells.
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Academic Article
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B cell immunodeficiency fails to develop in CD4-deficient mice infected with BM5: murine AIDS as a multistep disease.
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Academic Article
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Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis.
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Academic Article
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Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis.
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Academic Article
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In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines.
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Academic Article
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CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function.
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Academic Article
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Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells.
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Academic Article
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Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation.
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Academic Article
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CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency.
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Academic Article
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Class II-independent generation of CD4 memory T cells from effectors.
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Academic Article
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Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells.
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Academic Article
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Repeated stimulation of CD4 effector T cells can limit their protective function.
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Academic Article
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IL-4 directs the development of Th2-like helper effectors.
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Academic Article
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Helper cells activated by allogeneic H-2K or H-2D differences have a Ly phenotype distinct from those responsive to I differences.
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Academic Article
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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge.
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Academic Article
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Negative allogeneic effects in vitro. II. Mapping of histocompatibility differences leading to allosuppression.
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Academic Article
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SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation.
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Academic Article
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Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses.
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Academic Article
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Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.
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Academic Article
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Stimulation of gut-associated lymphoid cells by IL-4 and B-cell growth factor II.
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Academic Article
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Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma.
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Academic Article
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Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells.
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Academic Article
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Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects.
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Academic Article
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Induction of the H-2 D antigen during B cell activation.
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Academic Article
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Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype.
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Academic Article
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Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms.
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Academic Article
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Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors.
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Academic Article
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The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12.
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Academic Article
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Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes.
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Academic Article
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B cell surface glycoprotein induced during growth response: molecular structure and expression pattern.
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Academic Article
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B cell response to fresh and effector T helper cells. Role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6.
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Academic Article
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Fine specificity mapping of two allospecific T cell lines: recognition of private specificities in the H-2 IA subregion.
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Academic Article
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Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens.
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Academic Article
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Immunosuppressive ATS. V. Analysis of the effect of anti-thymocyte serum on T lymphocyte subsets.
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Academic Article
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Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line.
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Academic Article
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Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor.
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Academic Article
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IL-7 promotes the transition of CD4 effectors to persistent memory cells.
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Academic Article
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Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin.
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Academic Article
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Generation and in vivo persistence of polarized Th1 and Th2 memory cells.
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Academic Article
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Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs.
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Academic Article
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Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.
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Academic Article
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Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease.
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Academic Article
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Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen.
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Academic Article
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Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
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Academic Article
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CD4 T cells producing IFN-gamma in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype.
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Academic Article
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Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates.
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Academic Article
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Uneven distribution of MHC class II epitopes within the influenza virus.
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Academic Article
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Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection.
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Academic Article
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Mechanism of allosuppression: evidence for direct suppression of responding B cells.
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Academic Article
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Frequency of allogeneic helper T cells responding to whole H-2 differences and to an H-2K difference alone.
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Academic Article
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Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response.
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Academic Article
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The effector to memory transition of CD4 T cells.
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Academic Article
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Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2.
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Academic Article
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IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.
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Academic Article
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Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell.
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Academic Article
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Memory CD4+ T cells induce innate responses independently of pathogen.
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Academic Article
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TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism.
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Academic Article
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Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection.
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Academic Article
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Multiple redundant effector mechanisms of CD8+ T cells protect against influenza infection.
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Academic Article
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B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.
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Academic Article
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Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection.
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Academic Article
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Regulation of the immune response T-cell interactions.
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Academic Article
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Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses.
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Academic Article
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Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response.
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Academic Article
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Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays.
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Academic Article
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Partial purification and characterization of a BCGFII from EL4 culture supernatants.
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Academic Article
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Production of Con A-induced helper T cell replacing factor requires a T cell and an Ia-positive non-T cells.
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Academic Article
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Role of Ia-positive cells in the production of T cell-replacing factors: blocking of factor production with anti-Ia serum.
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Academic Article
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Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.
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Academic Article
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A monoclonal T cell-replacing activity can act directly on B cells to enhance clonal expansion.
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Academic Article
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Alloreactivity, the development of the T cell repertoire and the understanding of T cell function.
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Academic Article
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Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.
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Academic Article
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The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro.
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Academic Article
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Role of antigen-presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophages.
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Concept
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Mice, Inbred CBA
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred NOD
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Concept
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Mice, Inbred A
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Concept
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Mice, Inbred AKR
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Inbred DBA
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Academic Article
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CD28 and ITK signals regulate autoreactive T cell trafficking.
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Academic Article
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Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2.
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Academic Article
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IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age.
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Academic Article
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IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells.
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Academic Article
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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
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Academic Article
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Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza.
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Academic Article
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IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans.
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Academic Article
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NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection.
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Academic Article
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IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo.
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Academic Article
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IL-15 supports the generation of protective lung-resident memory CD4 T cells.
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Academic Article
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The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age.
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Academic Article
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Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation.
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Academic Article
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Virus-induced natural killer cell lysis of T cell subsets.
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Academic Article
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CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation.
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Academic Article
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Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production.
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Academic Article
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Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection.
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Academic Article
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CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated.
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