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One or more keywords matched the following items that are connected to Gao, Fen-Biao
Item TypeName
Academic Article Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Academic Article FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions.
Academic Article GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function.
Academic Article Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts.
Academic Article Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.
Academic Article Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
Academic Article The epidemiology and genetics of Amyotrophic lateral sclerosis in China.
Academic Article p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Academic Article CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
Academic Article Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.
Concept C9orf72 Protein
Academic Article Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
Academic Article Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD.
Academic Article Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia.
Academic Article A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Academic Article The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD.
Academic Article Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons.
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  • C9orf72 Protein