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Academic Article
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Understanding fragile X syndrome: insights from retarded flies.
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Academic Article
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The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1.
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Academic Article
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Genes regulating dendritic outgrowth, branching, and routing in Drosophila.
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Academic Article
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Abelson, enabled, and p120 catenin exert distinct effects on dendritic morphogenesis in Drosophila.
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Academic Article
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Roles of ESCRT in autophagy-associated neurodegeneration.
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Academic Article
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Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
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Academic Article
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Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity.
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Academic Article
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Progranulin, a glycoprotein deficient in frontotemporal dementia, is a novel substrate of several protein disulfide isomerase family proteins.
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Academic Article
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Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
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Academic Article
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Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.
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Academic Article
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Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1.
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Academic Article
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Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia.
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Academic Article
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MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia.
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Academic Article
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Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS.
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Concept
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Vesicular Transport Proteins
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Concept
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Protein Binding
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Concept
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DNA-Binding Proteins
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Concept
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GTP-Binding Proteins
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Concept
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Carrier Proteins
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Concept
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rac1 GTP-Binding Protein
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Concept
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Calcium-Binding Proteins
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Concept
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RNA-Binding Proteins
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Academic Article
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Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.
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Academic Article
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Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila.
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Academic Article
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The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders.
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Academic Article
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RNA metabolism in neurological disease.
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Academic Article
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The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila
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Academic Article
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Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1
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Academic Article
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Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs
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Academic Article
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RNA-binding proteins in neurological disease
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Academic Article
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Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia.
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Academic Article
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Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila.
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Academic Article
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The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia.
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Academic Article
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Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells.
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Academic Article
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Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD.
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Academic Article
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Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila.
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Academic Article
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Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.
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Academic Article
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RNA targets of TDP-43: Which one is more important in neurodegeneration?
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