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Search Results to Bruce A Barton PhD

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Biography:

Dr. Barton was named Research Professor in UMass Medical School’s Department of Quantitative Health Sciences (Division of Biostatistics and Health Services Research) in 2010 and, subsequently, the Director of the Quantitative Methods Core. He has also served as the Team Leader of the Research Methods Team (Biostatistics) in the Center for Health Policy Research at UMMS and as an Adjunct Professor at Tufts School of Veterinary Medicine. Dr. Barton is a biostatistician with over 40 years of experience in medical research studies, especially randomized clinical trials, starting with the National Surgical Adjuvant Breast Project breast cancer clinical trials at the University of Pittsburgh in 1975. He has been the PI/Director of 31 Data Coordinating Centers during that time-frame, funded both by NIH and by industry. His experience in clinical trials includes multi-center/multi-national trials with patient-level and higher-level (cluster) randomizations.

He has served on over 150 NIH study sections over the past 30 years, including recently completing 4 years of service as a member of the NHLBI Clinical Trials Review Group. He has served on over 20 Data and Safety Monitoring Boards in a variety of content areas. At UMMS, he chairs the Library and Learning Resources Committee and co-chairs the Protocol Review Committee and the Data, Safety, and Accrual Monitoring Committee for the Cancer Research Office.

Prior to joining UMass in 2010, Dr. Barton served in various capacities during his 30 years as a statistician at the Maryland Medical Research Institute in Baltimore, including Senior Statistician for 20 years and Principal Statistician for four years. From 1998 to 2009, he also held multiple leadership roles at the  Institute. From 1999 to 2003, he taught biostatistics courses at Johns Hopkins University, both in class and online; in 2010, he resumed teaching biostatistics online at Johns Hopkins.

Academic Background:

Ph.D. (Biostatistics) University of Pittsburgh, Pittsburgh, PA

M.S.(Hyg) (Biostatistics) University of Pittsburgh, Pittsburgh, PA

M.A. (Classical Languages) The Pennsylvania State University, State College, PA

B.A. (Latin/Greek) Dickinson College, Carlisle, PA              

Research:

Dr. Barton’s research interests include: sickle cell disease; cardiology and cardiovascular disease; oncology; hepatitis C and alcoholic hepatitis; emergency medicine; diabetes; and animal science. He has published widely on growth and development in children, including measures of anthropometry and cardiovascular disease risk factors, and the relationship of nutrition, physical activity, and psychosocial factors to anthropometry. He has also been involved in studies of Transcendental Meditation and its effect on both cardiovascular disease risk factors and cardiovascular disease itself. His statistical research interests include clinical trial methodology, longitudinal data analysis, handling of missing data in longitudinal studies,   and efficient study designs for early phase (Phase I and II) clinical trials.

Most recently, he had been the PI/Director of the Data Coordinating Centers for: Hip Impact Protection Program (HIP PRO), Silent Infarct Transfusion Trial (SITT), Multicenter Study of Hydroxyurea (MSH) Patients Follow-up, Pegylated Interferon ± Ribavirin for Children with HCV (PEDS-C), Occluded Artery Trial (OAT), Low Magnitude Mechanical Stimulation to Improve Bone Mass Density (VIBES), Atlantic C-PORT Elective PCI Trial, and, currently,  Studies in Alcoholic Hepatitis (two clinical trials assessing treatment in patients with moderate or with severe alcoholic hepatitis) and the KidSteps II: Promoting school readiness through social emotional skill building in preschool. He also serves as the lead statistician on numerous other studies. His background in clinical trials includes the design and development oversight of trial infrastructure, including data management, randomization/drug inventory management systems, ePRO systems (using IVRS/IWRS technology), development of case report forms, monitoring of data through statistical process control approaches, analysis (both oversight and personal performance) using SAS, and developing the tables, listings, and figures for publications.

Dr. Barton also has previous experience and is currently working with biopharmaceutical companies to design and implement studies (Phases I-III) and to provide analysis and support for submissions (including NDAs) to the FDA. 

Other Affiliations:

Center for Health Policy and Research


One or more keywords matched the following items that are connected to Barton, Bruce

Item TypeName
Academic Article Differential classification of blood pressure by fourth and fifth Korotkoff phases in school-aged girls. The National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Sexual maturation and racial differences in blood pressure in girls: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Race, socioeconomic status, and obesity in 9- to 10-year-old girls: the NHLBI Growth and Health Study.
Academic Article Lipoprotein and apolipoprotein differences in black and white girls. The National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Safety of a fat-reduced diet: the Dietary Intervention Study in Children (DISC).
Academic Article Effects of diet and sexual maturation on low-density lipoprotein cholesterol during puberty: the Dietary Intervention Study in Children (DISC).
Academic Article The conjoint trait of low high-density lipoprotein cholesterol and high triglycerides in adolescent black and white males.
Academic Article Overweight, fat patterning, and cardiovascular disease risk factors in black and white boys.
Academic Article Efficacy and safety of lowering dietary intake of total fat, saturated fat, and cholesterol in children with elevated LDL cholesterol: the Dietary Intervention Study in Children.
Academic Article Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol: seven-year results of the Dietary Intervention Study in Children (DISC).
Academic Article Racial divergence in adiposity during adolescence: The NHLBI Growth and Health Study.
Academic Article Impact of timing of pubertal maturation on growth in black and white female adolescents: The National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Racial differences in the sums of skinfolds and percentage of body fat estimated from impedance in black and white girls, 9 to 19 years of age: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Nutrient intake and blood pressure in the Dietary Intervention Study in Children.
Academic Article Self-esteem and adiposity in black and white girls: the NHLBI Growth and Health Study.
Academic Article Longitudinal correlates of change in blood pressure in adolescent girls.
Academic Article Metformin for weight loss in pediatric patients taking psychotropic drugs.
Academic Article Diet and sex hormones in girls: findings from a randomized controlled clinical trial.
Academic Article Macronutrient intake of black and white adolescent girls over 10 years: the NHLBI Growth and Health Study.
Academic Article Measuring eating concerns in Black and White adolescent girls.
Academic Article Overweight, fat patterning, and cardiovascular disease risk factors in black and white girls: The National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Children's adaptations to a fat-reduced diet: the Dietary Intervention Study in Children (DISC).
Academic Article Relation between the changes in physical activity and body-mass index during adolescence: a multicentre longitudinal study.
Academic Article The relationship of breakfast and cereal consumption to nutrient intake and body mass index: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Fruit and vegetable intake: Few adolescent girls meet national guidelines.
Academic Article Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Longitudinal changes in physical activity in a biracial cohort during adolescence.
Academic Article Higher self-reported physical activity is associated with lower systolic blood pressure: the Dietary Intervention Study in Childhood (DISC).
Academic Article A randomized, double-blind, placebo-controlled trial of metformin treatment of weight gain associated with initiation of atypical antipsychotic therapy in children and adolescents.
Academic Article Influence of intervention on beverage choices: trends in the dietary intervention study in children (DISC).
Academic Article Longitudinal assessment of micronutrient intake among African-American and white girls: The National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Morphine analgesia and gastrointestinal morbidity in preterm infants: secondary results from the NEOPAIN trial.
Academic Article Major gene effect and additive familial pattern of inheritance of asthma exist among families of probands with sickle cell anemia and asthma.
Academic Article Silent Cerebral Infarct Transfusion (SIT) trial imaging core: application of novel imaging information technology for rapid and central review of MRI of the brain.
Academic Article Concern over ready-to-eat breakfast cereals.
Academic Article Consumption of breakfast cereal is associated with positive health outcomes: evidence from the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Impact of hepatitis C virus infection on children and their caregivers: quality of life, cognitive, and emotional outcomes.
Academic Article Prospective associations among cereal intake in childhood and adiposity, lipid levels, and physical activity during late adolescence.
Academic Article Design of the silent cerebral infarct transfusion (SIT) trial.
Academic Article Adolescent diet and subsequent serum hormones, breast density, and bone mineral density in young women: results of the Dietary Intervention Study in Children follow-up study.
Academic Article Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children.
Academic Article Adolescent diet and metabolic syndrome in young women: results of the Dietary Intervention Study in Children (DISC) follow-up study.
Academic Article Pegylated interferon for chronic hepatitis C in children affects growth and body composition: results from the pediatric study of hepatitis C (PEDS-C) trial.
Academic Article Recruitment and retention strategies in a clinical trial for children with chronic hepatitis C infection.
Academic Article Decline in physical activity in black girls and white girls during adolescence.
Academic Article Obesity development during adolescence in a biracial cohort: the NHLBI Growth and Health Study.
Academic Article Autoantibodies and autoimmune disease during treatment of children with chronic hepatitis C.
Academic Article A summary of results of the Dietary Intervention Study in Children (DISC): lessons learned.
Academic Article Sex hormones and the changes in adolescent male lipids: longitudinal studies in a biracial cohort.
Academic Article Pubertal maturation in girls and the relationship to anthropometric changes: pathways through puberty.
Academic Article Obesity and the development of insulin resistance and impaired fasting glucose in black and white adolescent girls: a longitudinal study.
Academic Article Mother-daughter correlations of obesity and cardiovascular disease risk factors in black and white households: the NHLBI Growth and Health Study.
Academic Article Sexual maturation and obesity in 9- and 10-year-old black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Changes in weight and body image over time in women with eating disorders.
Academic Article Expanding our understanding of the relationship between negative life events and depressive symptoms in black and white adolescent girls.
Academic Article Breakfast consumption by African-American and white adolescent girls correlates positively with calcium and fiber intake and negatively with body mass index.
Academic Article Fast-food intake and diet quality in black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article An empirical study of the typology of bulimia nervosa and its spectrum variants.
Academic Article Caffeine intake in eating disorders.
Academic Article Development of the metabolic syndrome in black and white adolescent girls: a longitudinal assessment.
Academic Article Pubertal correlates in black and white girls.
Academic Article Diet and sex hormones in boys: findings from the dietary intervention study in children.
Academic Article Childhood overweight and cardiovascular disease risk factors: the National Heart, Lung, and Blood Institute Growth and Health Study.
Academic Article Design of the PEDS-C trial: pegylated interferon +/- ribavirin for children with chronic hepatitis C viral infection.
Academic Article The relationship of ready-to-eat cereal consumption to nutrient intake, blood lipids, and body mass index of children as they age through adolescence.
Academic Article The combination of ribavirin and peginterferon is superior to peginterferon and placebo for children and adolescents with chronic hepatitis C.
Academic Article Concerns regarding power and other analysis issues.
Academic Article The need for pediatric surgeons as determined by the volume of work and the mode of delivery of surgical care.
Concept Child Nutrition Sciences
Concept Child Behavior
Concept Child Development
Concept Child Nutritional Physiological Phenomena
Concept Child, Preschool
Concept Child
Concept Child Welfare
Academic Article Evaluating progression of liver disease from repeat liver biopsies in children with chronic hepatitis C: a retrospective study.
Academic Article Personal and parental weight misperception and self-reported attempted weight loss in US children and adolescents, National Health and Nutrition Examination Survey, 2007-2008 and 2009-2010.
Academic Article Prevalence and risk factors for postpartum depression symptoms among women with disabilities.
Academic Article A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes.
Academic Article Use of a FITLINE to Support Families of Overweight and Obese Children in Pediatric Practices.
Academic Article Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis.
Academic Article Partial clinical remission in type 1 diabetes: a comparison of the accuracy of total daily dose of insulin of <0.3 units/kg/day to the gold standard insulin-dose adjusted hemoglobin A1c of =9 for the detection of partial clinical remission.
Academic Article A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes.
Academic Article The health of women and children in South Carolina: success or crisis?
Academic Article School-age children's safety attitudes, cognitions, knowledge, and injury experiences: how do these relate to their safety practices?

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