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Latz, Eicke

One or more keywords matched the following items that are connected to Latz, Eicke

Item Type	Name
Academic Article	Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Academic Article	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Academic Article	Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Academic Article	Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
Academic Article	The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Academic Article	Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Academic Article	SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Academic Article	The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Academic Article	Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Academic Article	Intracellular DNA recognition.
Academic Article	IFI16 is an innate immune sensor for intracellular DNA.
Academic Article	The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Academic Article	Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
Academic Article	Innate immune receptors for nucleic acids.
Academic Article	Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair.
Academic Article	For gut's sake: NLRC4 inflammasomes distinguish friend from foe.
Academic Article	NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Academic Article	Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.
Academic Article	CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Academic Article	LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Academic Article	TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Academic Article	Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Academic Article	Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
Academic Article	Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.
Academic Article	Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Academic Article	AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Academic Article	Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Academic Article	The inflammasomes: mechanisms of activation and function.
Academic Article	Critical functions of priming and lysosomal damage for NLRP3 activation.
Academic Article	Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Academic Article	The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Academic Article	NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Academic Article	Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Academic Article	NLRP3 inflammasomes link inflammation and metabolic disease.
Academic Article	Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Academic Article	Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Academic Article	PKR stirs up inflammasomes.
Academic Article	Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes.
Academic Article	Activation and regulation of the inflammasomes.
Concept	Protein Binding
Concept	DNA-Binding Proteins
Concept	Phosphate-Binding Proteins
Concept	Carrier Proteins
Concept	rhoA GTP-Binding Protein
Concept	rab GTP-Binding Proteins
Concept	Membrane Transport Proteins
Concept	Calcium-Binding Proteins
Concept	RNA-Binding Proteins
Academic Article	HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages.
Academic Article	RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Academic Article	New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease.
Academic Article	Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Academic Article	Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Academic Article	Innate immune activation in neurodegenerative disease.
Academic Article	The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Academic Article	LOX-1 and mitochondria: an inflammatory relationship.
Academic Article	Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Academic Article	NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1?.
Academic Article	A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Academic Article	Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage.
Academic Article	Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation.
Academic Article	ATF3 Is a Key Regulator of Macrophage IFN Responses.
Academic Article	Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET.
Academic Article	Assembly and regulation of ASC specks.
Academic Article	Statins improve NASH via inhibition of RhoA and Ras.
Academic Article	NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
Academic Article	Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Academic Article	Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Academic Article	The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Academic Article	AIM2 inflammasome-derived IL-1? induces postoperative ileus in mice.
Academic Article	Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.
Academic Article	Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
Academic Article	The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles.
Academic Article	Sensing soluble uric acid by Naip1-Nlrp3 platform.
Concept	Fatty Acid Binding Protein 3

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Carrier Proteins